8GYK

CryoEM structure of the RAD51_ADP filament

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000150	molecular_function	DNA strand exchange activity
A	0000152	cellular_component	nuclear ubiquitin ligase complex
A	0000166	molecular_function	nucleotide binding
A	0000228	cellular_component	nuclear chromosome
A	0000722	biological_process	telomere maintenance via recombination
A	0000724	biological_process	double-strand break repair via homologous recombination
A	0000730	biological_process	DNA recombinase assembly
A	0000781	cellular_component	chromosome, telomeric region
A	0000785	cellular_component	chromatin
A	0000793	cellular_component	condensed chromosome
A	0000794	cellular_component	condensed nuclear chromosome
A	0000800	cellular_component	lateral element
A	0001673	cellular_component	male germ cell nucleus
A	0003677	molecular_function	DNA binding
A	0003682	molecular_function	chromatin binding
A	0003690	molecular_function	double-stranded DNA binding
A	0003697	molecular_function	single-stranded DNA binding
A	0005515	molecular_function	protein binding
A	0005524	molecular_function	ATP binding
A	0005634	cellular_component	nucleus
A	0005654	cellular_component	nucleoplasm
A	0005694	cellular_component	chromosome
A	0005730	cellular_component	nucleolus
A	0005737	cellular_component	cytoplasm
A	0005739	cellular_component	mitochondrion
A	0005759	cellular_component	mitochondrial matrix
A	0005813	cellular_component	centrosome
A	0005829	cellular_component	cytosol
A	0005856	cellular_component	cytoskeleton
A	0006259	biological_process	DNA metabolic process
A	0006268	biological_process	DNA unwinding involved in DNA replication
A	0006281	biological_process	DNA repair
A	0006310	biological_process	DNA recombination
A	0006312	biological_process	mitotic recombination
A	0006974	biological_process	DNA damage response
A	0007127	biological_process	meiosis I
A	0007131	biological_process	reciprocal meiotic recombination
A	0008094	molecular_function	ATP-dependent activity, acting on DNA
A	0009410	biological_process	response to xenobiotic stimulus
A	0009636	biological_process	response to toxic substance
A	0010165	biological_process	response to X-ray
A	0010569	biological_process	regulation of double-strand break repair via homologous recombination
A	0010833	biological_process	telomere maintenance via telomere lengthening
A	0014070	biological_process	response to organic cyclic compound
A	0016605	cellular_component	PML body
A	0016887	molecular_function	ATP hydrolysis activity
A	0017116	molecular_function	single-stranded DNA helicase activity
A	0019899	molecular_function	enzyme binding
A	0031297	biological_process	replication fork processing
A	0032200	biological_process	telomere organization
A	0032991	cellular_component	protein-containing complex
A	0035861	cellular_component	site of double-strand break
A	0036297	biological_process	interstrand cross-link repair
A	0042148	biological_process	DNA strand invasion
A	0042802	molecular_function	identical protein binding
A	0048471	cellular_component	perinuclear region of cytoplasm
A	0051106	biological_process	positive regulation of DNA ligation
A	0051321	biological_process	meiotic cell cycle
A	0070182	molecular_function	DNA polymerase binding
A	0070192	biological_process	chromosome organization involved in meiotic cell cycle
A	0071312	biological_process	cellular response to alkaloid
A	0071479	biological_process	cellular response to ionizing radiation
A	0071480	biological_process	cellular response to gamma radiation
A	0072711	biological_process	cellular response to hydroxyurea
A	0072719	biological_process	cellular response to cisplatin
A	0072757	biological_process	cellular response to camptothecin
A	0099182	cellular_component	presynaptic intermediate filament cytoskeleton
A	0140664	molecular_function	ATP-dependent DNA damage sensor activity
A	1904631	biological_process	response to glucoside
A	1990414	biological_process	replication-born double-strand break repair via sister chromatid exchange
A	1990426	biological_process	mitotic recombination-dependent replication fork processing
A	1990918	biological_process	double-strand break repair involved in meiotic recombination
A	2000001	biological_process	regulation of DNA damage checkpoint
B	0000150	molecular_function	DNA strand exchange activity
B	0000152	cellular_component	nuclear ubiquitin ligase complex
B	0000166	molecular_function	nucleotide binding
B	0000228	cellular_component	nuclear chromosome
B	0000722	biological_process	telomere maintenance via recombination
B	0000724	biological_process	double-strand break repair via homologous recombination
B	0000730	biological_process	DNA recombinase assembly
B	0000781	cellular_component	chromosome, telomeric region
B	0000785	cellular_component	chromatin
B	0000793	cellular_component	condensed chromosome
B	0000794	cellular_component	condensed nuclear chromosome
B	0000800	cellular_component	lateral element
B	0001673	cellular_component	male germ cell nucleus
B	0003677	molecular_function	DNA binding
B	0003682	molecular_function	chromatin binding
B	0003690	molecular_function	double-stranded DNA binding
B	0003697	molecular_function	single-stranded DNA binding
B	0005515	molecular_function	protein binding
B	0005524	molecular_function	ATP binding
B	0005634	cellular_component	nucleus
B	0005654	cellular_component	nucleoplasm
B	0005694	cellular_component	chromosome
B	0005730	cellular_component	nucleolus
B	0005737	cellular_component	cytoplasm
B	0005739	cellular_component	mitochondrion
B	0005759	cellular_component	mitochondrial matrix
B	0005813	cellular_component	centrosome
B	0005829	cellular_component	cytosol
B	0005856	cellular_component	cytoskeleton
B	0006259	biological_process	DNA metabolic process
B	0006268	biological_process	DNA unwinding involved in DNA replication
B	0006281	biological_process	DNA repair
B	0006310	biological_process	DNA recombination
B	0006312	biological_process	mitotic recombination
B	0006974	biological_process	DNA damage response
B	0007127	biological_process	meiosis I
B	0007131	biological_process	reciprocal meiotic recombination
B	0008094	molecular_function	ATP-dependent activity, acting on DNA
B	0009410	biological_process	response to xenobiotic stimulus
B	0009636	biological_process	response to toxic substance
B	0010165	biological_process	response to X-ray
B	0010569	biological_process	regulation of double-strand break repair via homologous recombination
B	0010833	biological_process	telomere maintenance via telomere lengthening
B	0014070	biological_process	response to organic cyclic compound
B	0016605	cellular_component	PML body
B	0016887	molecular_function	ATP hydrolysis activity
B	0017116	molecular_function	single-stranded DNA helicase activity
B	0019899	molecular_function	enzyme binding
B	0031297	biological_process	replication fork processing
B	0032200	biological_process	telomere organization
B	0032991	cellular_component	protein-containing complex
B	0035861	cellular_component	site of double-strand break
B	0036297	biological_process	interstrand cross-link repair
B	0042148	biological_process	DNA strand invasion
B	0042802	molecular_function	identical protein binding
B	0048471	cellular_component	perinuclear region of cytoplasm
B	0051106	biological_process	positive regulation of DNA ligation
B	0051321	biological_process	meiotic cell cycle
B	0070182	molecular_function	DNA polymerase binding
B	0070192	biological_process	chromosome organization involved in meiotic cell cycle
B	0071312	biological_process	cellular response to alkaloid
B	0071479	biological_process	cellular response to ionizing radiation
B	0071480	biological_process	cellular response to gamma radiation
B	0072711	biological_process	cellular response to hydroxyurea
B	0072719	biological_process	cellular response to cisplatin
B	0072757	biological_process	cellular response to camptothecin
B	0099182	cellular_component	presynaptic intermediate filament cytoskeleton
B	0140664	molecular_function	ATP-dependent DNA damage sensor activity
B	1904631	biological_process	response to glucoside
B	1990414	biological_process	replication-born double-strand break repair via sister chromatid exchange
B	1990426	biological_process	mitotic recombination-dependent replication fork processing
B	1990918	biological_process	double-strand break repair involved in meiotic recombination
B	2000001	biological_process	regulation of DNA damage checkpoint
C	0000150	molecular_function	DNA strand exchange activity
C	0000152	cellular_component	nuclear ubiquitin ligase complex
C	0000166	molecular_function	nucleotide binding
C	0000228	cellular_component	nuclear chromosome
C	0000722	biological_process	telomere maintenance via recombination
C	0000724	biological_process	double-strand break repair via homologous recombination
C	0000730	biological_process	DNA recombinase assembly
C	0000781	cellular_component	chromosome, telomeric region
C	0000785	cellular_component	chromatin
C	0000793	cellular_component	condensed chromosome
C	0000794	cellular_component	condensed nuclear chromosome
C	0000800	cellular_component	lateral element
C	0001673	cellular_component	male germ cell nucleus
C	0003677	molecular_function	DNA binding
C	0003682	molecular_function	chromatin binding
C	0003690	molecular_function	double-stranded DNA binding
C	0003697	molecular_function	single-stranded DNA binding
C	0005515	molecular_function	protein binding
C	0005524	molecular_function	ATP binding
C	0005634	cellular_component	nucleus
C	0005654	cellular_component	nucleoplasm
C	0005694	cellular_component	chromosome
C	0005730	cellular_component	nucleolus
C	0005737	cellular_component	cytoplasm
C	0005739	cellular_component	mitochondrion
C	0005759	cellular_component	mitochondrial matrix
C	0005813	cellular_component	centrosome
C	0005829	cellular_component	cytosol
C	0005856	cellular_component	cytoskeleton
C	0006259	biological_process	DNA metabolic process
C	0006268	biological_process	DNA unwinding involved in DNA replication
C	0006281	biological_process	DNA repair
C	0006310	biological_process	DNA recombination
C	0006312	biological_process	mitotic recombination
C	0006974	biological_process	DNA damage response
C	0007127	biological_process	meiosis I
C	0007131	biological_process	reciprocal meiotic recombination
C	0008094	molecular_function	ATP-dependent activity, acting on DNA
C	0009410	biological_process	response to xenobiotic stimulus
C	0009636	biological_process	response to toxic substance
C	0010165	biological_process	response to X-ray
C	0010569	biological_process	regulation of double-strand break repair via homologous recombination
C	0010833	biological_process	telomere maintenance via telomere lengthening
C	0014070	biological_process	response to organic cyclic compound
C	0016605	cellular_component	PML body
C	0016887	molecular_function	ATP hydrolysis activity
C	0017116	molecular_function	single-stranded DNA helicase activity
C	0019899	molecular_function	enzyme binding
C	0031297	biological_process	replication fork processing
C	0032200	biological_process	telomere organization
C	0032991	cellular_component	protein-containing complex
C	0035861	cellular_component	site of double-strand break
C	0036297	biological_process	interstrand cross-link repair
C	0042148	biological_process	DNA strand invasion
C	0042802	molecular_function	identical protein binding
C	0048471	cellular_component	perinuclear region of cytoplasm
C	0051106	biological_process	positive regulation of DNA ligation
C	0051321	biological_process	meiotic cell cycle
C	0070182	molecular_function	DNA polymerase binding
C	0070192	biological_process	chromosome organization involved in meiotic cell cycle
C	0071312	biological_process	cellular response to alkaloid
C	0071479	biological_process	cellular response to ionizing radiation
C	0071480	biological_process	cellular response to gamma radiation
C	0072711	biological_process	cellular response to hydroxyurea
C	0072719	biological_process	cellular response to cisplatin
C	0072757	biological_process	cellular response to camptothecin
C	0099182	cellular_component	presynaptic intermediate filament cytoskeleton
C	0140664	molecular_function	ATP-dependent DNA damage sensor activity
C	1904631	biological_process	response to glucoside
C	1990414	biological_process	replication-born double-strand break repair via sister chromatid exchange
C	1990426	biological_process	mitotic recombination-dependent replication fork processing
C	1990918	biological_process	double-strand break repair involved in meiotic recombination
C	2000001	biological_process	regulation of DNA damage checkpoint
D	0000150	molecular_function	DNA strand exchange activity
D	0000152	cellular_component	nuclear ubiquitin ligase complex
D	0000166	molecular_function	nucleotide binding
D	0000228	cellular_component	nuclear chromosome
D	0000722	biological_process	telomere maintenance via recombination
D	0000724	biological_process	double-strand break repair via homologous recombination
D	0000730	biological_process	DNA recombinase assembly
D	0000781	cellular_component	chromosome, telomeric region
D	0000785	cellular_component	chromatin
D	0000793	cellular_component	condensed chromosome
D	0000794	cellular_component	condensed nuclear chromosome
D	0000800	cellular_component	lateral element
D	0001673	cellular_component	male germ cell nucleus
D	0003677	molecular_function	DNA binding
D	0003682	molecular_function	chromatin binding
D	0003690	molecular_function	double-stranded DNA binding
D	0003697	molecular_function	single-stranded DNA binding
D	0005515	molecular_function	protein binding
D	0005524	molecular_function	ATP binding
D	0005634	cellular_component	nucleus
D	0005654	cellular_component	nucleoplasm
D	0005694	cellular_component	chromosome
D	0005730	cellular_component	nucleolus
D	0005737	cellular_component	cytoplasm
D	0005739	cellular_component	mitochondrion
D	0005759	cellular_component	mitochondrial matrix
D	0005813	cellular_component	centrosome
D	0005829	cellular_component	cytosol
D	0005856	cellular_component	cytoskeleton
D	0006259	biological_process	DNA metabolic process
D	0006268	biological_process	DNA unwinding involved in DNA replication
D	0006281	biological_process	DNA repair
D	0006310	biological_process	DNA recombination
D	0006312	biological_process	mitotic recombination
D	0006974	biological_process	DNA damage response
D	0007127	biological_process	meiosis I
D	0007131	biological_process	reciprocal meiotic recombination
D	0008094	molecular_function	ATP-dependent activity, acting on DNA
D	0009410	biological_process	response to xenobiotic stimulus
D	0009636	biological_process	response to toxic substance
D	0010165	biological_process	response to X-ray
D	0010569	biological_process	regulation of double-strand break repair via homologous recombination
D	0010833	biological_process	telomere maintenance via telomere lengthening
D	0014070	biological_process	response to organic cyclic compound
D	0016605	cellular_component	PML body
D	0016887	molecular_function	ATP hydrolysis activity
D	0017116	molecular_function	single-stranded DNA helicase activity
D	0019899	molecular_function	enzyme binding
D	0031297	biological_process	replication fork processing
D	0032200	biological_process	telomere organization
D	0032991	cellular_component	protein-containing complex
D	0035861	cellular_component	site of double-strand break
D	0036297	biological_process	interstrand cross-link repair
D	0042148	biological_process	DNA strand invasion
D	0042802	molecular_function	identical protein binding
D	0048471	cellular_component	perinuclear region of cytoplasm
D	0051106	biological_process	positive regulation of DNA ligation
D	0051321	biological_process	meiotic cell cycle
D	0070182	molecular_function	DNA polymerase binding
D	0070192	biological_process	chromosome organization involved in meiotic cell cycle
D	0071312	biological_process	cellular response to alkaloid
D	0071479	biological_process	cellular response to ionizing radiation
D	0071480	biological_process	cellular response to gamma radiation
D	0072711	biological_process	cellular response to hydroxyurea
D	0072719	biological_process	cellular response to cisplatin
D	0072757	biological_process	cellular response to camptothecin
D	0099182	cellular_component	presynaptic intermediate filament cytoskeleton
D	0140664	molecular_function	ATP-dependent DNA damage sensor activity
D	1904631	biological_process	response to glucoside
D	1990414	biological_process	replication-born double-strand break repair via sister chromatid exchange
D	1990426	biological_process	mitotic recombination-dependent replication fork processing
D	1990918	biological_process	double-strand break repair involved in meiotic recombination
D	2000001	biological_process	regulation of DNA damage checkpoint
E	0000150	molecular_function	DNA strand exchange activity
E	0000152	cellular_component	nuclear ubiquitin ligase complex
E	0000166	molecular_function	nucleotide binding
E	0000228	cellular_component	nuclear chromosome
E	0000722	biological_process	telomere maintenance via recombination
E	0000724	biological_process	double-strand break repair via homologous recombination
E	0000730	biological_process	DNA recombinase assembly
E	0000781	cellular_component	chromosome, telomeric region
E	0000785	cellular_component	chromatin
E	0000793	cellular_component	condensed chromosome
E	0000794	cellular_component	condensed nuclear chromosome
E	0000800	cellular_component	lateral element
E	0001673	cellular_component	male germ cell nucleus
E	0003677	molecular_function	DNA binding
E	0003682	molecular_function	chromatin binding
E	0003690	molecular_function	double-stranded DNA binding
E	0003697	molecular_function	single-stranded DNA binding
E	0005515	molecular_function	protein binding
E	0005524	molecular_function	ATP binding
E	0005634	cellular_component	nucleus
E	0005654	cellular_component	nucleoplasm
E	0005694	cellular_component	chromosome
E	0005730	cellular_component	nucleolus
E	0005737	cellular_component	cytoplasm
E	0005739	cellular_component	mitochondrion
E	0005759	cellular_component	mitochondrial matrix
E	0005813	cellular_component	centrosome
E	0005829	cellular_component	cytosol
E	0005856	cellular_component	cytoskeleton
E	0006259	biological_process	DNA metabolic process
E	0006268	biological_process	DNA unwinding involved in DNA replication
E	0006281	biological_process	DNA repair
E	0006310	biological_process	DNA recombination
E	0006312	biological_process	mitotic recombination
E	0006974	biological_process	DNA damage response
E	0007127	biological_process	meiosis I
E	0007131	biological_process	reciprocal meiotic recombination
E	0008094	molecular_function	ATP-dependent activity, acting on DNA
E	0009410	biological_process	response to xenobiotic stimulus
E	0009636	biological_process	response to toxic substance
E	0010165	biological_process	response to X-ray
E	0010569	biological_process	regulation of double-strand break repair via homologous recombination
E	0010833	biological_process	telomere maintenance via telomere lengthening
E	0014070	biological_process	response to organic cyclic compound
E	0016605	cellular_component	PML body
E	0016887	molecular_function	ATP hydrolysis activity
E	0017116	molecular_function	single-stranded DNA helicase activity
E	0019899	molecular_function	enzyme binding
E	0031297	biological_process	replication fork processing
E	0032200	biological_process	telomere organization
E	0032991	cellular_component	protein-containing complex
E	0035861	cellular_component	site of double-strand break
E	0036297	biological_process	interstrand cross-link repair
E	0042148	biological_process	DNA strand invasion
E	0042802	molecular_function	identical protein binding
E	0048471	cellular_component	perinuclear region of cytoplasm
E	0051106	biological_process	positive regulation of DNA ligation
E	0051321	biological_process	meiotic cell cycle
E	0070182	molecular_function	DNA polymerase binding
E	0070192	biological_process	chromosome organization involved in meiotic cell cycle
E	0071312	biological_process	cellular response to alkaloid
E	0071479	biological_process	cellular response to ionizing radiation
E	0071480	biological_process	cellular response to gamma radiation
E	0072711	biological_process	cellular response to hydroxyurea
E	0072719	biological_process	cellular response to cisplatin
E	0072757	biological_process	cellular response to camptothecin
E	0099182	cellular_component	presynaptic intermediate filament cytoskeleton
E	0140664	molecular_function	ATP-dependent DNA damage sensor activity
E	1904631	biological_process	response to glucoside
E	1990414	biological_process	replication-born double-strand break repair via sister chromatid exchange
E	1990426	biological_process	mitotic recombination-dependent replication fork processing
E	1990918	biological_process	double-strand break repair involved in meiotic recombination
E	2000001	biological_process	regulation of DNA damage checkpoint
F	0000150	molecular_function	DNA strand exchange activity
F	0000152	cellular_component	nuclear ubiquitin ligase complex
F	0000166	molecular_function	nucleotide binding
F	0000228	cellular_component	nuclear chromosome
F	0000722	biological_process	telomere maintenance via recombination
F	0000724	biological_process	double-strand break repair via homologous recombination
F	0000730	biological_process	DNA recombinase assembly
F	0000781	cellular_component	chromosome, telomeric region
F	0000785	cellular_component	chromatin
F	0000793	cellular_component	condensed chromosome
F	0000794	cellular_component	condensed nuclear chromosome
F	0000800	cellular_component	lateral element
F	0001673	cellular_component	male germ cell nucleus
F	0003677	molecular_function	DNA binding
F	0003682	molecular_function	chromatin binding
F	0003690	molecular_function	double-stranded DNA binding
F	0003697	molecular_function	single-stranded DNA binding
F	0005515	molecular_function	protein binding
F	0005524	molecular_function	ATP binding
F	0005634	cellular_component	nucleus
F	0005654	cellular_component	nucleoplasm
F	0005694	cellular_component	chromosome
F	0005730	cellular_component	nucleolus
F	0005737	cellular_component	cytoplasm
F	0005739	cellular_component	mitochondrion
F	0005759	cellular_component	mitochondrial matrix
F	0005813	cellular_component	centrosome
F	0005829	cellular_component	cytosol
F	0005856	cellular_component	cytoskeleton
F	0006259	biological_process	DNA metabolic process
F	0006268	biological_process	DNA unwinding involved in DNA replication
F	0006281	biological_process	DNA repair
F	0006310	biological_process	DNA recombination
F	0006312	biological_process	mitotic recombination
F	0006974	biological_process	DNA damage response
F	0007127	biological_process	meiosis I
F	0007131	biological_process	reciprocal meiotic recombination
F	0008094	molecular_function	ATP-dependent activity, acting on DNA
F	0009410	biological_process	response to xenobiotic stimulus
F	0009636	biological_process	response to toxic substance
F	0010165	biological_process	response to X-ray
F	0010569	biological_process	regulation of double-strand break repair via homologous recombination
F	0010833	biological_process	telomere maintenance via telomere lengthening
F	0014070	biological_process	response to organic cyclic compound
F	0016605	cellular_component	PML body
F	0016887	molecular_function	ATP hydrolysis activity
F	0017116	molecular_function	single-stranded DNA helicase activity
F	0019899	molecular_function	enzyme binding
F	0031297	biological_process	replication fork processing
F	0032200	biological_process	telomere organization
F	0032991	cellular_component	protein-containing complex
F	0035861	cellular_component	site of double-strand break
F	0036297	biological_process	interstrand cross-link repair
F	0042148	biological_process	DNA strand invasion
F	0042802	molecular_function	identical protein binding
F	0048471	cellular_component	perinuclear region of cytoplasm
F	0051106	biological_process	positive regulation of DNA ligation
F	0051321	biological_process	meiotic cell cycle
F	0070182	molecular_function	DNA polymerase binding
F	0070192	biological_process	chromosome organization involved in meiotic cell cycle
F	0071312	biological_process	cellular response to alkaloid
F	0071479	biological_process	cellular response to ionizing radiation
F	0071480	biological_process	cellular response to gamma radiation
F	0072711	biological_process	cellular response to hydroxyurea
F	0072719	biological_process	cellular response to cisplatin
F	0072757	biological_process	cellular response to camptothecin
F	0099182	cellular_component	presynaptic intermediate filament cytoskeleton
F	0140664	molecular_function	ATP-dependent DNA damage sensor activity
F	1904631	biological_process	response to glucoside
F	1990414	biological_process	replication-born double-strand break repair via sister chromatid exchange
F	1990426	biological_process	mitotic recombination-dependent replication fork processing
F	1990918	biological_process	double-strand break repair involved in meiotic recombination
F	2000001	biological_process	regulation of DNA damage checkpoint
G	0000150	molecular_function	DNA strand exchange activity
G	0000152	cellular_component	nuclear ubiquitin ligase complex
G	0000166	molecular_function	nucleotide binding
G	0000228	cellular_component	nuclear chromosome
G	0000722	biological_process	telomere maintenance via recombination
G	0000724	biological_process	double-strand break repair via homologous recombination
G	0000730	biological_process	DNA recombinase assembly
G	0000781	cellular_component	chromosome, telomeric region
G	0000785	cellular_component	chromatin
G	0000793	cellular_component	condensed chromosome
G	0000794	cellular_component	condensed nuclear chromosome
G	0000800	cellular_component	lateral element
G	0001673	cellular_component	male germ cell nucleus
G	0003677	molecular_function	DNA binding
G	0003682	molecular_function	chromatin binding
G	0003690	molecular_function	double-stranded DNA binding
G	0003697	molecular_function	single-stranded DNA binding
G	0005515	molecular_function	protein binding
G	0005524	molecular_function	ATP binding
G	0005634	cellular_component	nucleus
G	0005654	cellular_component	nucleoplasm
G	0005694	cellular_component	chromosome
G	0005730	cellular_component	nucleolus
G	0005737	cellular_component	cytoplasm
G	0005739	cellular_component	mitochondrion
G	0005759	cellular_component	mitochondrial matrix
G	0005813	cellular_component	centrosome
G	0005829	cellular_component	cytosol
G	0005856	cellular_component	cytoskeleton
G	0006259	biological_process	DNA metabolic process
G	0006268	biological_process	DNA unwinding involved in DNA replication
G	0006281	biological_process	DNA repair
G	0006310	biological_process	DNA recombination
G	0006312	biological_process	mitotic recombination
G	0006974	biological_process	DNA damage response
G	0007127	biological_process	meiosis I
G	0007131	biological_process	reciprocal meiotic recombination
G	0008094	molecular_function	ATP-dependent activity, acting on DNA
G	0009410	biological_process	response to xenobiotic stimulus
G	0009636	biological_process	response to toxic substance
G	0010165	biological_process	response to X-ray
G	0010569	biological_process	regulation of double-strand break repair via homologous recombination
G	0010833	biological_process	telomere maintenance via telomere lengthening
G	0014070	biological_process	response to organic cyclic compound
G	0016605	cellular_component	PML body
G	0016887	molecular_function	ATP hydrolysis activity
G	0017116	molecular_function	single-stranded DNA helicase activity
G	0019899	molecular_function	enzyme binding
G	0031297	biological_process	replication fork processing
G	0032200	biological_process	telomere organization
G	0032991	cellular_component	protein-containing complex
G	0035861	cellular_component	site of double-strand break
G	0036297	biological_process	interstrand cross-link repair
G	0042148	biological_process	DNA strand invasion
G	0042802	molecular_function	identical protein binding
G	0048471	cellular_component	perinuclear region of cytoplasm
G	0051106	biological_process	positive regulation of DNA ligation
G	0051321	biological_process	meiotic cell cycle
G	0070182	molecular_function	DNA polymerase binding
G	0070192	biological_process	chromosome organization involved in meiotic cell cycle
G	0071312	biological_process	cellular response to alkaloid
G	0071479	biological_process	cellular response to ionizing radiation
G	0071480	biological_process	cellular response to gamma radiation
G	0072711	biological_process	cellular response to hydroxyurea
G	0072719	biological_process	cellular response to cisplatin
G	0072757	biological_process	cellular response to camptothecin
G	0099182	cellular_component	presynaptic intermediate filament cytoskeleton
G	0140664	molecular_function	ATP-dependent DNA damage sensor activity
G	1904631	biological_process	response to glucoside
G	1990414	biological_process	replication-born double-strand break repair via sister chromatid exchange
G	1990426	biological_process	mitotic recombination-dependent replication fork processing
G	1990918	biological_process	double-strand break repair involved in meiotic recombination
G	2000001	biological_process	regulation of DNA damage checkpoint
H	0000150	molecular_function	DNA strand exchange activity
H	0000152	cellular_component	nuclear ubiquitin ligase complex
H	0000166	molecular_function	nucleotide binding
H	0000228	cellular_component	nuclear chromosome
H	0000722	biological_process	telomere maintenance via recombination
H	0000724	biological_process	double-strand break repair via homologous recombination
H	0000730	biological_process	DNA recombinase assembly
H	0000781	cellular_component	chromosome, telomeric region
H	0000785	cellular_component	chromatin
H	0000793	cellular_component	condensed chromosome
H	0000794	cellular_component	condensed nuclear chromosome
H	0000800	cellular_component	lateral element
H	0001673	cellular_component	male germ cell nucleus
H	0003677	molecular_function	DNA binding
H	0003682	molecular_function	chromatin binding
H	0003690	molecular_function	double-stranded DNA binding
H	0003697	molecular_function	single-stranded DNA binding
H	0005515	molecular_function	protein binding
H	0005524	molecular_function	ATP binding
H	0005634	cellular_component	nucleus
H	0005654	cellular_component	nucleoplasm
H	0005694	cellular_component	chromosome
H	0005730	cellular_component	nucleolus
H	0005737	cellular_component	cytoplasm
H	0005739	cellular_component	mitochondrion
H	0005759	cellular_component	mitochondrial matrix
H	0005813	cellular_component	centrosome
H	0005829	cellular_component	cytosol
H	0005856	cellular_component	cytoskeleton
H	0006259	biological_process	DNA metabolic process
H	0006268	biological_process	DNA unwinding involved in DNA replication
H	0006281	biological_process	DNA repair
H	0006310	biological_process	DNA recombination
H	0006312	biological_process	mitotic recombination
H	0006974	biological_process	DNA damage response
H	0007127	biological_process	meiosis I
H	0007131	biological_process	reciprocal meiotic recombination
H	0008094	molecular_function	ATP-dependent activity, acting on DNA
H	0009410	biological_process	response to xenobiotic stimulus
H	0009636	biological_process	response to toxic substance
H	0010165	biological_process	response to X-ray
H	0010569	biological_process	regulation of double-strand break repair via homologous recombination
H	0010833	biological_process	telomere maintenance via telomere lengthening
H	0014070	biological_process	response to organic cyclic compound
H	0016605	cellular_component	PML body
H	0016887	molecular_function	ATP hydrolysis activity
H	0017116	molecular_function	single-stranded DNA helicase activity
H	0019899	molecular_function	enzyme binding
H	0031297	biological_process	replication fork processing
H	0032200	biological_process	telomere organization
H	0032991	cellular_component	protein-containing complex
H	0035861	cellular_component	site of double-strand break
H	0036297	biological_process	interstrand cross-link repair
H	0042148	biological_process	DNA strand invasion
H	0042802	molecular_function	identical protein binding
H	0048471	cellular_component	perinuclear region of cytoplasm
H	0051106	biological_process	positive regulation of DNA ligation
H	0051321	biological_process	meiotic cell cycle
H	0070182	molecular_function	DNA polymerase binding
H	0070192	biological_process	chromosome organization involved in meiotic cell cycle
H	0071312	biological_process	cellular response to alkaloid
H	0071479	biological_process	cellular response to ionizing radiation
H	0071480	biological_process	cellular response to gamma radiation
H	0072711	biological_process	cellular response to hydroxyurea
H	0072719	biological_process	cellular response to cisplatin
H	0072757	biological_process	cellular response to camptothecin
H	0099182	cellular_component	presynaptic intermediate filament cytoskeleton
H	0140664	molecular_function	ATP-dependent DNA damage sensor activity
H	1904631	biological_process	response to glucoside
H	1990414	biological_process	replication-born double-strand break repair via sister chromatid exchange
H	1990426	biological_process	mitotic recombination-dependent replication fork processing
H	1990918	biological_process	double-strand break repair involved in meiotic recombination
H	2000001	biological_process	regulation of DNA damage checkpoint

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	8
Details	BINDING: BINDING => ECO:0000255

Chain	Residue	Details
A	GLY127
B	GLY127
C	GLY127
D	GLY127
E	GLY127
F	GLY127
G	GLY127
H	GLY127

---

site_id	SWS_FT_FI2
Number of Residues	8
Details	MOD_RES: N-acetylalanine => ECO:0007744|PubMed:22814378

Chain	Residue	Details
A	ALA2
B	ALA2
C	ALA2
D	ALA2
E	ALA2
F	ALA2
G	ALA2
H	ALA2

---

site_id	SWS_FT_FI3
Number of Residues	8
Details	MOD_RES: Phosphothreonine; by CK2 => ECO:0000269|PubMed:22325354, ECO:0000269|PubMed:26811421

Chain	Residue	Details
A	THR13
B	THR13
C	THR13
D	THR13
E	THR13
F	THR13
G	THR13
H	THR13

---

site_id	SWS_FT_FI4
Number of Residues	8
Details	MOD_RES: Phosphoserine; by PLK1 => ECO:0000269|PubMed:22325354, ECO:0000269|PubMed:26811421

Chain	Residue	Details
A	SER14
B	SER14
C	SER14
D	SER14
E	SER14
F	SER14
G	SER14
H	SER14

---

site_id	SWS_FT_FI5
Number of Residues	8
Details	MOD_RES: Phosphotyrosine; by ABL1 => ECO:0000269|PubMed:9461559

Chain	Residue	Details
A	TYR54
B	TYR54
C	TYR54
D	TYR54
E	TYR54
F	TYR54
G	TYR54
H	TYR54

---

site_id	SWS_FT_FI6
Number of Residues	8
Details	MOD_RES: Phosphothreonine; by CHEK1 => ECO:0000269|PubMed:15665856

Chain	Residue	Details
A	THR309
B	THR309
C	THR309
D	THR309
E	THR309
F	THR309
G	THR309
H	THR309

---

site_id	SWS_FT_FI7
Number of Residues	24
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:23393192

Chain	Residue	Details
A	LYS58
D	LYS58
D	LYS64
E	LYS58
E	LYS64
F	LYS58
F	LYS64
G	LYS58
G	LYS64
H	LYS58
H	LYS64
A	LYS64
B	LYS58
B	LYS64
C	LYS58
C	LYS64

---