8GBQ
Structure of RNF125 in complex with UbcH5b
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000151 | cellular_component | ubiquitin ligase complex |
| A | 0000209 | biological_process | protein polyubiquitination |
| A | 0004842 | molecular_function | ubiquitin-protein transferase activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005634 | cellular_component | nucleus |
| A | 0005654 | cellular_component | nucleoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0006511 | biological_process | ubiquitin-dependent protein catabolic process |
| A | 0016567 | biological_process | protein ubiquitination |
| A | 0016740 | molecular_function | transferase activity |
| A | 0019787 | molecular_function | ubiquitin-like protein transferase activity |
| A | 0031625 | molecular_function | ubiquitin protein ligase binding |
| A | 0032991 | cellular_component | protein-containing complex |
| A | 0036211 | biological_process | protein modification process |
| A | 0051865 | biological_process | protein autoubiquitination |
| A | 0061630 | molecular_function | ubiquitin protein ligase activity |
| A | 0061631 | molecular_function | ubiquitin conjugating enzyme activity |
| A | 0070062 | cellular_component | extracellular exosome |
| A | 0070936 | biological_process | protein K48-linked ubiquitination |
Functional Information from PROSITE/UniProt
| site_id | PS00518 |
| Number of Residues | 10 |
| Details | ZF_RING_1 Zinc finger RING-type signature. CgHvFCrsCI |
| Chain | Residue | Details |
| B | CYS52-ILE61 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 39 |
| Details | ZN_FING: RING-type => ECO:0000255|PROSITE-ProRule:PRU00175 |
| Chain | Residue | Details |
| B | CYS37-ARG76 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 19 |
| Details | ZN_FING: C2HC RNF-type => ECO:0000255|PROSITE-ProRule:PRU01144, ECO:0000303|PubMed:17990982 |
| Chain | Residue | Details |
| B | CYS100-CYS119 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 8 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:27411375, ECO:0007744|PDB:5DKA |
| Chain | Residue | Details |
| B | CYS37 | |
| B | CYS40 | |
| B | CYS52 | |
| B | HIS54 | |
| B | CYS57 | |
| B | CYS60 | |
| B | CYS72 | |
| B | CYS75 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU01144, ECO:0000269|PubMed:27411375, ECO:0007744|PDB:5DKA |
| Chain | Residue | Details |
| B | CYS100 | |
| B | CYS103 | |
| B | HIS115 | |
| B | CYS119 |
