8G2W

Cryo-EM structure of 3DVA component 2 of Escherichia coli que-PEC (paused elongation complex) RNA Polymerase minus preQ1 ligand

Functional Information from GO Data

Chain	GOid	namespace	contents
G	0003677	molecular_function	DNA binding
G	0003899	molecular_function	DNA-directed 5'-3' RNA polymerase activity
G	0006351	biological_process	DNA-templated transcription
G	0046983	molecular_function	protein dimerization activity
H	0003677	molecular_function	DNA binding
H	0003899	molecular_function	DNA-directed 5'-3' RNA polymerase activity
H	0006351	biological_process	DNA-templated transcription
H	0046983	molecular_function	protein dimerization activity
I	0000345	cellular_component	cytosolic DNA-directed RNA polymerase complex
I	0000428	cellular_component	DNA-directed RNA polymerase complex
I	0001054	molecular_function	RNA polymerase I activity
I	0001055	molecular_function	RNA polymerase II activity
I	0001056	molecular_function	RNA polymerase III activity
I	0001057	molecular_function	RNA polymerase IV activity
I	0001058	molecular_function	RNA polymerase V activity
I	0001059	biological_process	transcription by RNA polymerase IV
I	0001060	biological_process	transcription by RNA polymerase V
I	0001066	molecular_function	plastid single subunit type RNA polymerase activity
I	0003677	molecular_function	DNA binding
I	0003899	molecular_function	DNA-directed 5'-3' RNA polymerase activity
I	0005515	molecular_function	protein binding
I	0005737	cellular_component	cytoplasm
I	0005829	cellular_component	cytosol
I	0006351	biological_process	DNA-templated transcription
I	0006352	biological_process	DNA-templated transcription initiation
I	0006360	biological_process	transcription by RNA polymerase I
I	0006366	biological_process	transcription by RNA polymerase II
I	0006383	biological_process	transcription by RNA polymerase III
I	0006879	biological_process	intracellular iron ion homeostasis
I	0008023	cellular_component	transcription elongation factor complex
I	0009408	biological_process	response to heat
I	0016020	cellular_component	membrane
I	0016779	molecular_function	nucleotidyltransferase activity
I	0031564	biological_process	transcription antitermination
I	0032549	molecular_function	ribonucleoside binding
I	0032784	biological_process	regulation of DNA-templated transcription elongation
I	0034062	molecular_function	5'-3' RNA polymerase activity
I	0036460	biological_process	cellular response to cell envelope stress
I	0042128	biological_process	nitrate assimilation
I	0042793	biological_process	plastid transcription
I	0044780	biological_process	bacterial-type flagellum assembly
I	0046677	biological_process	response to antibiotic
I	0048870	biological_process	cell motility
I	0071973	biological_process	bacterial-type flagellum-dependent cell motility
I	0090605	biological_process	submerged biofilm formation
I	2000142	biological_process	regulation of DNA-templated transcription initiation
J	0000287	molecular_function	magnesium ion binding
J	0000345	cellular_component	cytosolic DNA-directed RNA polymerase complex
J	0000428	cellular_component	DNA-directed RNA polymerase complex
J	0001054	molecular_function	RNA polymerase I activity
J	0001055	molecular_function	RNA polymerase II activity
J	0001056	molecular_function	RNA polymerase III activity
J	0001057	molecular_function	RNA polymerase IV activity
J	0001058	molecular_function	RNA polymerase V activity
J	0001059	biological_process	transcription by RNA polymerase IV
J	0001060	biological_process	transcription by RNA polymerase V
J	0001066	molecular_function	plastid single subunit type RNA polymerase activity
J	0003677	molecular_function	DNA binding
J	0003899	molecular_function	DNA-directed 5'-3' RNA polymerase activity
J	0005515	molecular_function	protein binding
J	0005737	cellular_component	cytoplasm
J	0005829	cellular_component	cytosol
J	0006351	biological_process	DNA-templated transcription
J	0006352	biological_process	DNA-templated transcription initiation
J	0006360	biological_process	transcription by RNA polymerase I
J	0006366	biological_process	transcription by RNA polymerase II
J	0006383	biological_process	transcription by RNA polymerase III
J	0006879	biological_process	intracellular iron ion homeostasis
J	0008023	cellular_component	transcription elongation factor complex
J	0008270	molecular_function	zinc ion binding
J	0009408	biological_process	response to heat
J	0016020	cellular_component	membrane
J	0016779	molecular_function	nucleotidyltransferase activity
J	0031564	biological_process	transcription antitermination
J	0032784	biological_process	regulation of DNA-templated transcription elongation
J	0034062	molecular_function	5'-3' RNA polymerase activity
J	0036460	biological_process	cellular response to cell envelope stress
J	0042128	biological_process	nitrate assimilation
J	0042793	biological_process	plastid transcription
J	0044780	biological_process	bacterial-type flagellum assembly
J	0046677	biological_process	response to antibiotic
J	0046872	molecular_function	metal ion binding
J	0048870	biological_process	cell motility
J	0071973	biological_process	bacterial-type flagellum-dependent cell motility
J	0090605	biological_process	submerged biofilm formation
J	2000142	biological_process	regulation of DNA-templated transcription initiation
K	0003677	molecular_function	DNA binding
K	0003899	molecular_function	DNA-directed 5'-3' RNA polymerase activity
K	0006351	biological_process	DNA-templated transcription

Functional Information from PROSITE/UniProt

site_id	PS01166
Number of Residues	13
Details	RNA_POL_BETA RNA polymerases beta chain signature. GdKMAGrHGNKGV

Chain	Residue	Details
I	GLY1063-VAL1075

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	11
Details	BINDING: BINDING => ECO:0000269|PubMed:32871103, ECO:0007744|PDB:4MEX, ECO:0007744|PDB:4MEY

Chain	Residue	Details
J	CYS70
J	CYS895
J	CYS898
J	CYS72
J	CYS85
J	CYS88
J	ASP460
J	ASP462
J	ASP464
J	CYS814
J	CYS888

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site_id	SWS_FT_FI2
Number of Residues	1
Details	MOD_RES: N6-acetyllysine => ECO:0000255|HAMAP-Rule:MF_01322, ECO:0000269|PubMed:18723842

Chain	Residue	Details
J	LYS983

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