8FYY
Crystal structure of human PARP1 ART domain bound to inhibitor UKTT5 (compound 10)
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0003950 | molecular_function | NAD+-protein poly-ADP-ribosyltransferase activity |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 1 |
Details | ACT_SITE: For poly [ADP-ribose] polymerase activity => ECO:0000305|PubMed:32028527, ECO:0000305|PubMed:7852410, ECO:0000305|PubMed:9315851 |
Chain | Residue | Details |
A | GLU988 |
site_id | SWS_FT_FI2 |
Number of Residues | 4 |
Details | BINDING: BINDING => ECO:0000250|UniProtKB:Q9UGN5 |
Chain | Residue | Details |
A | HIS862 | |
A | GLY871 | |
A | ARG878 | |
A | SER904 |