8FPJ

Co-structure of the Human Metapneunomovirus RNA-dependent RNA polymerase with MRK-1

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0001172	biological_process	RNA-templated transcription
A	0003924	molecular_function	GTPase activity
A	0003968	molecular_function	RNA-dependent RNA polymerase activity
A	0004482	molecular_function	mRNA 5'-cap (guanine-N7-)-methyltransferase activity
A	0005524	molecular_function	ATP binding
A	0006370	biological_process	7-methylguanosine mRNA capping
A	0008168	molecular_function	methyltransferase activity
A	0016787	molecular_function	hydrolase activity
A	0030430	cellular_component	host cell cytoplasm
A	0032259	biological_process	methylation
A	0034062	molecular_function	5'-3' RNA polymerase activity
A	0044423	cellular_component	virion component
A	0046872	molecular_function	metal ion binding
A	0106005	biological_process	RNA 5'-cap (guanine-N7)-methylation
B	0001172	biological_process	RNA-templated transcription
B	0003968	molecular_function	RNA-dependent RNA polymerase activity
B	0030430	cellular_component	host cell cytoplasm
B	0044423	cellular_component	virion component
C	0001172	biological_process	RNA-templated transcription
C	0003968	molecular_function	RNA-dependent RNA polymerase activity
C	0030430	cellular_component	host cell cytoplasm
C	0044423	cellular_component	virion component
D	0001172	biological_process	RNA-templated transcription
D	0003968	molecular_function	RNA-dependent RNA polymerase activity
D	0030430	cellular_component	host cell cytoplasm
D	0044423	cellular_component	virion component
E	0001172	biological_process	RNA-templated transcription
E	0003968	molecular_function	RNA-dependent RNA polymerase activity
E	0030430	cellular_component	host cell cytoplasm
E	0044423	cellular_component	virion component

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	24
Details	MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:P03421

Chain	Residue	Details
B	SER106
C	SER158
C	SER168
C	SER171
D	SER106
D	SER148
D	SER157
D	SER158
D	SER168
D	SER171
E	SER106
B	SER148
E	SER148
E	SER157
E	SER158
E	SER168
E	SER171
B	SER157
B	SER158
B	SER168
B	SER171
C	SER106
C	SER148
C	SER157

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site_id	SWS_FT_FI2
Number of Residues	4
Details	ACT_SITE: For mRNA (nucleoside-2'-O-)-methyltransferase activity => ECO:0000269|PubMed:25056882

Chain	Residue	Details
A	LYS1673
A	ASP1779
A	LYS1817
A	GLU1848

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site_id	SWS_FT_FI3
Number of Residues	1
Details	BINDING: BINDING => ECO:0000250|UniProtKB:P28887

Chain	Residue	Details
A	ASP635

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site_id	SWS_FT_FI4
Number of Residues	1
Details	BINDING: BINDING => ECO:0000305|PubMed:31698413

Chain	Residue	Details
A	ASP745

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site_id	SWS_FT_FI5
Number of Residues	1
Details	BINDING: BINDING => ECO:0000269|PubMed:25056882

Chain	Residue	Details
A	GLY1696

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