8FPI

Co-structure of the Respiratory Syncytial Virus RNA-dependent RNA polymerase with MRK-1

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003968	molecular_function	RNA-dependent RNA polymerase activity
A	0004482	molecular_function	mRNA 5'-cap (guanine-N7-)-methyltransferase activity
A	0005524	molecular_function	ATP binding
A	0006370	biological_process	7-methylguanosine mRNA capping
B	0001172	biological_process	RNA-templated transcription
B	0003968	molecular_function	RNA-dependent RNA polymerase activity
B	0005515	molecular_function	protein binding
B	0019058	biological_process	viral life cycle
B	0030430	cellular_component	host cell cytoplasm
B	0044423	cellular_component	virion component
B	0085034	biological_process	symbiont-mediated suppression of host NF-kappaB cascade
C	0001172	biological_process	RNA-templated transcription
C	0003968	molecular_function	RNA-dependent RNA polymerase activity
C	0005515	molecular_function	protein binding
C	0019058	biological_process	viral life cycle
C	0030430	cellular_component	host cell cytoplasm
C	0044423	cellular_component	virion component
C	0085034	biological_process	symbiont-mediated suppression of host NF-kappaB cascade
D	0001172	biological_process	RNA-templated transcription
D	0003968	molecular_function	RNA-dependent RNA polymerase activity
D	0005515	molecular_function	protein binding
D	0019058	biological_process	viral life cycle
D	0030430	cellular_component	host cell cytoplasm
D	0044423	cellular_component	virion component
D	0085034	biological_process	symbiont-mediated suppression of host NF-kappaB cascade
E	0001172	biological_process	RNA-templated transcription
E	0003968	molecular_function	RNA-dependent RNA polymerase activity
E	0005515	molecular_function	protein binding
E	0019058	biological_process	viral life cycle
E	0030430	cellular_component	host cell cytoplasm
E	0044423	cellular_component	virion component
E	0085034	biological_process	symbiont-mediated suppression of host NF-kappaB cascade

Functional Information from PROSITE/UniProt

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YGCIVYH

Chain	Residue	Details
A	TYR249-HIS255

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	SITE: Interaction with protein M2-1

Chain	Residue	Details
B	THR108
C	THR108
D	THR108
E	THR108

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site_id	SWS_FT_FI2
Number of Residues	4
Details	MOD_RES: Phosphothreonine; by host => ECO:0000269|PubMed:17098979

Chain	Residue	Details
B	THR108
C	THR108
D	THR108
E	THR108

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site_id	SWS_FT_FI3
Number of Residues	20
Details	MOD_RES: Phosphoserine; by host => ECO:0000269|PubMed:12368320, ECO:0000269|PubMed:26474524

Chain	Residue	Details
B	SER116
C	SER237
D	SER116
D	SER117
D	SER119
D	SER232
D	SER237
E	SER116
E	SER117
E	SER119
E	SER232
B	SER117
E	SER237
B	SER119
B	SER232
B	SER237
C	SER116
C	SER117
C	SER119
C	SER232

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