Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

8FLE

Human nuclear pre-60S ribosomal subunit (State L2)

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
BE	0000027	biological_process	ribosomal large subunit assembly
BE	0000122	biological_process	negative regulation of transcription by RNA polymerase II
BE	0002181	biological_process	cytoplasmic translation
BE	0003723	molecular_function	RNA binding
BE	0003735	molecular_function	structural constituent of ribosome
BE	0005515	molecular_function	protein binding
BE	0005634	cellular_component	nucleus
BE	0005737	cellular_component	cytoplasm
BE	0005783	cellular_component	endoplasmic reticulum
BE	0005790	cellular_component	smooth endoplasmic reticulum
BE	0005829	cellular_component	cytosol
BE	0005840	cellular_component	ribosome
BE	0006412	biological_process	translation
BE	0006417	biological_process	regulation of translation
BE	0016020	cellular_component	membrane
BE	0022625	cellular_component	cytosolic large ribosomal subunit
BE	0022626	cellular_component	cytosolic ribosome
BE	0032991	cellular_component	protein-containing complex
BE	0043066	biological_process	negative regulation of apoptotic process
BE	0045182	molecular_function	translation regulator activity
BE	1990403	biological_process	embryonic brain development
BE	1990904	cellular_component	ribonucleoprotein complex
L5	0000027	biological_process	ribosomal large subunit assembly
L5	0002181	biological_process	cytoplasmic translation
L5	0003723	molecular_function	RNA binding
L5	0003735	molecular_function	structural constituent of ribosome
L5	0005515	molecular_function	protein binding
L5	0005634	cellular_component	nucleus
L5	0005654	cellular_component	nucleoplasm
L5	0005730	cellular_component	nucleolus
L5	0005737	cellular_component	cytoplasm
L5	0005829	cellular_component	cytosol
L5	0005840	cellular_component	ribosome
L5	0006364	biological_process	rRNA processing
L5	0006412	biological_process	translation
L5	0006605	biological_process	protein targeting
L5	0008097	molecular_function	5S rRNA binding
L5	0010628	biological_process	positive regulation of gene expression
L5	0016020	cellular_component	membrane
L5	0019843	molecular_function	rRNA binding
L5	0022625	cellular_component	cytosolic large ribosomal subunit
L5	0022626	cellular_component	cytosolic ribosome
L5	0031625	molecular_function	ubiquitin protein ligase binding
L5	0032092	biological_process	positive regulation of protein binding
L5	0032435	biological_process	negative regulation of proteasomal ubiquitin-dependent protein catabolic process
L5	0032991	cellular_component	protein-containing complex
L5	0034504	biological_process	protein localization to nucleus
L5	0042273	biological_process	ribosomal large subunit biogenesis
L5	0050821	biological_process	protein stabilization
L5	0070062	cellular_component	extracellular exosome
L5	1901796	biological_process	regulation of signal transduction by p53 class mediator
L5	1901798	biological_process	positive regulation of signal transduction by p53 class mediator
L5	1904667	biological_process	negative regulation of ubiquitin protein ligase activity
L5	1990904	cellular_component	ribonucleoprotein complex
L5	1990948	molecular_function	ubiquitin ligase inhibitor activity
L5	2000059	biological_process	negative regulation of ubiquitin-dependent protein catabolic process
L5	2000435	biological_process	negative regulation of protein neddylation
L6	0001824	biological_process	blastocyst development
L6	0002181	biological_process	cytoplasmic translation
L6	0003723	molecular_function	RNA binding
L6	0003735	molecular_function	structural constituent of ribosome
L6	0005515	molecular_function	protein binding
L6	0005634	cellular_component	nucleus
L6	0005730	cellular_component	nucleolus
L6	0005737	cellular_component	cytoplasm
L6	0005783	cellular_component	endoplasmic reticulum
L6	0005829	cellular_component	cytosol
L6	0005840	cellular_component	ribosome
L6	0006412	biological_process	translation
L6	0016020	cellular_component	membrane
L6	0022625	cellular_component	cytosolic large ribosomal subunit
L6	0022626	cellular_component	cytosolic ribosome
L6	0045202	cellular_component	synapse
L6	0060348	biological_process	bone development
L6	1990904	cellular_component	ribonucleoprotein complex
L7	0002181	biological_process	cytoplasmic translation
L7	0003723	molecular_function	RNA binding
L7	0003729	molecular_function	mRNA binding
L7	0003735	molecular_function	structural constituent of ribosome
L7	0005634	cellular_component	nucleus
L7	0005730	cellular_component	nucleolus
L7	0005737	cellular_component	cytoplasm
L7	0005829	cellular_component	cytosol
L7	0005840	cellular_component	ribosome
L7	0005925	cellular_component	focal adhesion
L7	0006412	biological_process	translation
L7	0006417	biological_process	regulation of translation
L7	0015934	cellular_component	large ribosomal subunit
L7	0016020	cellular_component	membrane
L7	0017148	biological_process	negative regulation of translation
L7	0022625	cellular_component	cytosolic large ribosomal subunit
L7	0022626	cellular_component	cytosolic ribosome
L7	0032496	biological_process	response to lipopolysaccharide
L7	0042592	biological_process	homeostatic process
L7	0045202	cellular_component	synapse
L7	0048246	biological_process	macrophage chemotaxis
L7	0060425	biological_process	lung morphogenesis
L7	0071346	biological_process	cellular response to type II interferon
L7	0097452	cellular_component	GAIT complex
L7	1901194	biological_process	negative regulation of formation of translation preinitiation complex
L7	1990904	cellular_component	ribonucleoprotein complex
L8	0002181	biological_process	cytoplasmic translation
L8	0003723	molecular_function	RNA binding
L8	0003735	molecular_function	structural constituent of ribosome
L8	0005515	molecular_function	protein binding
L8	0005737	cellular_component	cytoplasm
L8	0005829	cellular_component	cytosol
L8	0005840	cellular_component	ribosome
L8	0006364	biological_process	rRNA processing
L8	0006412	biological_process	translation
L8	0014069	cellular_component	postsynaptic density
L8	0016020	cellular_component	membrane
L8	0022625	cellular_component	cytosolic large ribosomal subunit
L8	0022626	cellular_component	cytosolic ribosome
L8	0042273	biological_process	ribosomal large subunit biogenesis
L8	0045202	cellular_component	synapse
L8	0045296	molecular_function	cadherin binding
L8	0070062	cellular_component	extracellular exosome
L8	1990904	cellular_component	ribonucleoprotein complex
L9	0002181	biological_process	cytoplasmic translation
L9	0003723	molecular_function	RNA binding
L9	0003735	molecular_function	structural constituent of ribosome
L9	0005515	molecular_function	protein binding
L9	0005634	cellular_component	nucleus
L9	0005737	cellular_component	cytoplasm
L9	0005829	cellular_component	cytosol
L9	0005840	cellular_component	ribosome
L9	0006412	biological_process	translation
L9	0022625	cellular_component	cytosolic large ribosomal subunit
L9	0022626	cellular_component	cytosolic ribosome
L9	0031672	cellular_component	A band
L9	0044391	cellular_component	ribosomal subunit
L9	0045202	cellular_component	synapse
L9	0045296	molecular_function	cadherin binding
L9	0045471	biological_process	response to ethanol
L9	1990904	cellular_component	ribonucleoprotein complex
LA	0002181	biological_process	cytoplasmic translation
LA	0003723	molecular_function	RNA binding
LA	0003735	molecular_function	structural constituent of ribosome
LA	0005515	molecular_function	protein binding
LA	0005634	cellular_component	nucleus
LA	0005737	cellular_component	cytoplasm
LA	0005829	cellular_component	cytosol
LA	0005840	cellular_component	ribosome
LA	0006412	biological_process	translation
LA	0015934	cellular_component	large ribosomal subunit
LA	0022625	cellular_component	cytosolic large ribosomal subunit
LA	0022626	cellular_component	cytosolic ribosome
LA	1990904	cellular_component	ribonucleoprotein complex
LB	0002181	biological_process	cytoplasmic translation
LB	0003723	molecular_function	RNA binding
LB	0003735	molecular_function	structural constituent of ribosome
LB	0005515	molecular_function	protein binding
LB	0005634	cellular_component	nucleus
LB	0005730	cellular_component	nucleolus
LB	0005737	cellular_component	cytoplasm
LB	0005783	cellular_component	endoplasmic reticulum
LB	0005791	cellular_component	rough endoplasmic reticulum
LB	0005829	cellular_component	cytosol
LB	0005840	cellular_component	ribosome
LB	0005925	cellular_component	focal adhesion
LB	0006412	biological_process	translation
LB	0016020	cellular_component	membrane
LB	0022625	cellular_component	cytosolic large ribosomal subunit
LB	0022626	cellular_component	cytosolic ribosome
LB	0043232	cellular_component	intracellular non-membrane-bounded organelle
LB	1990904	cellular_component	ribonucleoprotein complex
LC	0002181	biological_process	cytoplasmic translation
LC	0003723	molecular_function	RNA binding
LC	0003735	molecular_function	structural constituent of ribosome
LC	0005515	molecular_function	protein binding
LC	0005737	cellular_component	cytoplasm
LC	0005829	cellular_component	cytosol
LC	0005840	cellular_component	ribosome
LC	0006412	biological_process	translation
LC	0016020	cellular_component	membrane
LC	0022625	cellular_component	cytosolic large ribosomal subunit
LC	0022626	cellular_component	cytosolic ribosome
LC	1990904	cellular_component	ribonucleoprotein complex
LD	0002181	biological_process	cytoplasmic translation
LD	0003723	molecular_function	RNA binding
LD	0003735	molecular_function	structural constituent of ribosome
LD	0005515	molecular_function	protein binding
LD	0005730	cellular_component	nucleolus
LD	0005737	cellular_component	cytoplasm
LD	0005829	cellular_component	cytosol
LD	0005840	cellular_component	ribosome
LD	0005925	cellular_component	focal adhesion
LD	0006412	biological_process	translation
LD	0016020	cellular_component	membrane
LD	0022625	cellular_component	cytosolic large ribosomal subunit
LD	0022626	cellular_component	cytosolic ribosome
LD	0045202	cellular_component	synapse
LD	1990904	cellular_component	ribonucleoprotein complex
LE	0002181	biological_process	cytoplasmic translation
LE	0003723	molecular_function	RNA binding
LE	0003735	molecular_function	structural constituent of ribosome
LE	0005515	molecular_function	protein binding
LE	0005737	cellular_component	cytoplasm
LE	0005783	cellular_component	endoplasmic reticulum
LE	0005829	cellular_component	cytosol
LE	0005840	cellular_component	ribosome
LE	0006412	biological_process	translation
LE	0016020	cellular_component	membrane
LE	0022625	cellular_component	cytosolic large ribosomal subunit
LE	0022626	cellular_component	cytosolic ribosome
LE	0045202	cellular_component	synapse
LE	1990904	cellular_component	ribonucleoprotein complex
LF	0002181	biological_process	cytoplasmic translation
LF	0003723	molecular_function	RNA binding
LF	0003735	molecular_function	structural constituent of ribosome
LF	0005515	molecular_function	protein binding
LF	0005634	cellular_component	nucleus
LF	0005737	cellular_component	cytoplasm
LF	0005829	cellular_component	cytosol
LF	0005840	cellular_component	ribosome
LF	0005925	cellular_component	focal adhesion
LF	0006412	biological_process	translation
LF	0008201	molecular_function	heparin binding
LF	0022625	cellular_component	cytosolic large ribosomal subunit
LF	0022626	cellular_component	cytosolic ribosome
LF	0042802	molecular_function	identical protein binding
LF	0045202	cellular_component	synapse
LF	0046632	biological_process	alpha-beta T cell differentiation
LF	0070062	cellular_component	extracellular exosome
LF	0098793	cellular_component	presynapse
LF	0098978	cellular_component	glutamatergic synapse
LF	0140236	biological_process	translation at presynapse
LF	1990904	cellular_component	ribonucleoprotein complex
LG	0000122	biological_process	negative regulation of transcription by RNA polymerase II
LG	0001223	molecular_function	transcription coactivator binding
LG	0002181	biological_process	cytoplasmic translation
LG	0003723	molecular_function	RNA binding
LG	0003735	molecular_function	structural constituent of ribosome
LG	0005515	molecular_function	protein binding
LG	0005654	cellular_component	nucleoplasm
LG	0005730	cellular_component	nucleolus
LG	0005737	cellular_component	cytoplasm
LG	0005829	cellular_component	cytosol
LG	0005840	cellular_component	ribosome
LG	0005925	cellular_component	focal adhesion
LG	0006412	biological_process	translation
LG	0006610	biological_process	ribosomal protein import into nucleus
LG	0008284	biological_process	positive regulation of cell population proliferation
LG	0010628	biological_process	positive regulation of gene expression
LG	0016020	cellular_component	membrane
LG	0022625	cellular_component	cytosolic large ribosomal subunit
LG	0022626	cellular_component	cytosolic ribosome
LG	0031625	molecular_function	ubiquitin protein ligase binding
LG	0032986	biological_process	protein-DNA complex disassembly
LG	0032991	cellular_component	protein-containing complex
LG	0045202	cellular_component	synapse
LG	0050821	biological_process	protein stabilization
LG	0070062	cellular_component	extracellular exosome
LG	0070180	molecular_function	large ribosomal subunit rRNA binding
LG	0070314	biological_process	G1 to G0 transition
LG	0072717	biological_process	cellular response to actinomycin D
LG	1901798	biological_process	positive regulation of signal transduction by p53 class mediator
LG	1903450	biological_process	regulation of G1 to G0 transition
LG	1904667	biological_process	negative regulation of ubiquitin protein ligase activity
LG	1990904	cellular_component	ribonucleoprotein complex
LG	1990948	molecular_function	ubiquitin ligase inhibitor activity
LG	2000059	biological_process	negative regulation of ubiquitin-dependent protein catabolic process
LH	0000027	biological_process	ribosomal large subunit assembly
LH	0002181	biological_process	cytoplasmic translation
LH	0003723	molecular_function	RNA binding
LH	0003735	molecular_function	structural constituent of ribosome
LH	0005515	molecular_function	protein binding
LH	0005634	cellular_component	nucleus
LH	0005730	cellular_component	nucleolus
LH	0005737	cellular_component	cytoplasm
LH	0005829	cellular_component	cytosol
LH	0005840	cellular_component	ribosome
LH	0006412	biological_process	translation
LH	0019843	molecular_function	rRNA binding
LH	0022625	cellular_component	cytosolic large ribosomal subunit
LH	0022626	cellular_component	cytosolic ribosome
LH	0045296	molecular_function	cadherin binding
LH	0070062	cellular_component	extracellular exosome
LH	1904841	molecular_function	TORC2 complex binding
LH	1990904	cellular_component	ribonucleoprotein complex
LI	0002181	biological_process	cytoplasmic translation
LI	0003723	molecular_function	RNA binding
LI	0003735	molecular_function	structural constituent of ribosome
LI	0005515	molecular_function	protein binding
LI	0005654	cellular_component	nucleoplasm
LI	0005730	cellular_component	nucleolus
LI	0005737	cellular_component	cytoplasm
LI	0005829	cellular_component	cytosol
LI	0005840	cellular_component	ribosome
LI	0006364	biological_process	rRNA processing
LI	0006412	biological_process	translation
LI	0006977	biological_process	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
LI	0015934	cellular_component	large ribosomal subunit
LI	0016020	cellular_component	membrane
LI	0022625	cellular_component	cytosolic large ribosomal subunit
LI	0022626	cellular_component	cytosolic ribosome
LI	0034644	biological_process	cellular response to UV
LI	0042273	biological_process	ribosomal large subunit biogenesis
LI	0045202	cellular_component	synapse
LI	0045727	biological_process	positive regulation of translation
LI	0048027	molecular_function	mRNA 5'-UTR binding
LI	0070062	cellular_component	extracellular exosome
LI	0071479	biological_process	cellular response to ionizing radiation
LI	0071480	biological_process	cellular response to gamma radiation
LI	1902164	biological_process	positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
LI	1902167	biological_process	positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
LI	1904803	biological_process	regulation of translation involved in cellular response to UV
LI	1990904	cellular_component	ribonucleoprotein complex
LJ	0002181	biological_process	cytoplasmic translation
LJ	0003723	molecular_function	RNA binding
LJ	0003735	molecular_function	structural constituent of ribosome
LJ	0005515	molecular_function	protein binding
LJ	0005634	cellular_component	nucleus
LJ	0005654	cellular_component	nucleoplasm
LJ	0005730	cellular_component	nucleolus
LJ	0005737	cellular_component	cytoplasm
LJ	0005783	cellular_component	endoplasmic reticulum
LJ	0005791	cellular_component	rough endoplasmic reticulum
LJ	0005829	cellular_component	cytosol
LJ	0005840	cellular_component	ribosome
LJ	0005925	cellular_component	focal adhesion
LJ	0006364	biological_process	rRNA processing
LJ	0006412	biological_process	translation
LJ	0016020	cellular_component	membrane
LJ	0022625	cellular_component	cytosolic large ribosomal subunit
LJ	0022626	cellular_component	cytosolic ribosome
LJ	0045202	cellular_component	synapse
LJ	0070062	cellular_component	extracellular exosome
LJ	0098556	cellular_component	cytoplasmic side of rough endoplasmic reticulum membrane
LJ	1904044	biological_process	response to aldosterone
LJ	1990904	cellular_component	ribonucleoprotein complex
LK	0002181	biological_process	cytoplasmic translation
LK	0003723	molecular_function	RNA binding
LK	0003735	molecular_function	structural constituent of ribosome
LK	0005515	molecular_function	protein binding
LK	0005654	cellular_component	nucleoplasm
LK	0005737	cellular_component	cytoplasm
LK	0005783	cellular_component	endoplasmic reticulum
LK	0005829	cellular_component	cytosol
LK	0005840	cellular_component	ribosome
LK	0006412	biological_process	translation
LK	0015934	cellular_component	large ribosomal subunit
LK	0016020	cellular_component	membrane
LK	0022625	cellular_component	cytosolic large ribosomal subunit
LK	0022626	cellular_component	cytosolic ribosome
LK	1990904	cellular_component	ribonucleoprotein complex
LL	0002181	biological_process	cytoplasmic translation
LL	0003723	molecular_function	RNA binding
LL	0003735	molecular_function	structural constituent of ribosome
LL	0005515	molecular_function	protein binding
LL	0005737	cellular_component	cytoplasm
LL	0005829	cellular_component	cytosol
LL	0005840	cellular_component	ribosome
LL	0006412	biological_process	translation
LL	0016020	cellular_component	membrane
LL	0022625	cellular_component	cytosolic large ribosomal subunit
LL	0022626	cellular_component	cytosolic ribosome
LL	0030425	cellular_component	dendrite
LL	0036464	cellular_component	cytoplasmic ribonucleoprotein granule
LL	0044297	cellular_component	cell body
LL	0045202	cellular_component	synapse
LL	0070062	cellular_component	extracellular exosome
LL	1990904	cellular_component	ribonucleoprotein complex
LM	0002181	biological_process	cytoplasmic translation
LM	0003723	molecular_function	RNA binding
LM	0003735	molecular_function	structural constituent of ribosome
LM	0005737	cellular_component	cytoplasm
LM	0005829	cellular_component	cytosol
LM	0005840	cellular_component	ribosome
LM	0006412	biological_process	translation
LM	0007566	biological_process	embryo implantation
LM	0008201	molecular_function	heparin binding
LM	0016020	cellular_component	membrane
LM	0022625	cellular_component	cytosolic large ribosomal subunit
LM	0022626	cellular_component	cytosolic ribosome
LM	0045296	molecular_function	cadherin binding
LM	1990904	cellular_component	ribonucleoprotein complex
LN	0002181	biological_process	cytoplasmic translation
LN	0003723	molecular_function	RNA binding
LN	0003735	molecular_function	structural constituent of ribosome
LN	0005515	molecular_function	protein binding
LN	0005634	cellular_component	nucleus
LN	0005730	cellular_component	nucleolus
LN	0005737	cellular_component	cytoplasm
LN	0005829	cellular_component	cytosol
LN	0005840	cellular_component	ribosome
LN	0005925	cellular_component	focal adhesion
LN	0006412	biological_process	translation
LN	0022625	cellular_component	cytosolic large ribosomal subunit
LN	0022626	cellular_component	cytosolic ribosome
LN	0032991	cellular_component	protein-containing complex
LN	0070062	cellular_component	extracellular exosome
LN	0071353	biological_process	cellular response to interleukin-4
LN	1990904	cellular_component	ribonucleoprotein complex
LO	0002181	biological_process	cytoplasmic translation
LO	0003723	molecular_function	RNA binding
LO	0003735	molecular_function	structural constituent of ribosome
LO	0005515	molecular_function	protein binding
LO	0005634	cellular_component	nucleus
LO	0005737	cellular_component	cytoplasm
LO	0005829	cellular_component	cytosol
LO	0005840	cellular_component	ribosome
LO	0005925	cellular_component	focal adhesion
LO	0006412	biological_process	translation
LO	0014069	cellular_component	postsynaptic density
LO	0016020	cellular_component	membrane
LO	0022625	cellular_component	cytosolic large ribosomal subunit
LO	0022626	cellular_component	cytosolic ribosome
LO	0031640	biological_process	killing of cells of another organism
LO	0045202	cellular_component	synapse
LO	0050829	biological_process	defense response to Gram-negative bacterium
LO	0061844	biological_process	antimicrobial humoral immune response mediated by antimicrobial peptide
LO	0070062	cellular_component	extracellular exosome
LO	1990904	cellular_component	ribonucleoprotein complex
LP	0002181	biological_process	cytoplasmic translation
LP	0003723	molecular_function	RNA binding
LP	0003735	molecular_function	structural constituent of ribosome
LP	0005515	molecular_function	protein binding
LP	0005737	cellular_component	cytoplasm
LP	0005829	cellular_component	cytosol
LP	0005840	cellular_component	ribosome
LP	0005925	cellular_component	focal adhesion
LP	0006412	biological_process	translation
LP	0016020	cellular_component	membrane
LP	0022625	cellular_component	cytosolic large ribosomal subunit
LP	0022626	cellular_component	cytosolic ribosome
LP	0070062	cellular_component	extracellular exosome
LP	1990904	cellular_component	ribonucleoprotein complex
LQ	0002181	biological_process	cytoplasmic translation
LQ	0003723	molecular_function	RNA binding
LQ	0003735	molecular_function	structural constituent of ribosome
LQ	0005737	cellular_component	cytoplasm
LQ	0005829	cellular_component	cytosol
LQ	0005840	cellular_component	ribosome
LQ	0006412	biological_process	translation
LQ	0016020	cellular_component	membrane
LQ	0022625	cellular_component	cytosolic large ribosomal subunit
LQ	0022626	cellular_component	cytosolic ribosome
LQ	1990904	cellular_component	ribonucleoprotein complex
LR	0002181	biological_process	cytoplasmic translation
LR	0003723	molecular_function	RNA binding
LR	0003735	molecular_function	structural constituent of ribosome
LR	0005515	molecular_function	protein binding
LR	0005730	cellular_component	nucleolus
LR	0005737	cellular_component	cytoplasm
LR	0005783	cellular_component	endoplasmic reticulum
LR	0005829	cellular_component	cytosol
LR	0005840	cellular_component	ribosome
LR	0006412	biological_process	translation
LR	0022625	cellular_component	cytosolic large ribosomal subunit
LR	0022626	cellular_component	cytosolic ribosome
LR	0045202	cellular_component	synapse
LR	0045296	molecular_function	cadherin binding
LR	0070062	cellular_component	extracellular exosome
LR	1990904	cellular_component	ribonucleoprotein complex
LS	0000463	biological_process	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
LS	0002181	biological_process	cytoplasmic translation
LS	0003723	molecular_function	RNA binding
LS	0003729	molecular_function	mRNA binding
LS	0003735	molecular_function	structural constituent of ribosome
LS	0005730	cellular_component	nucleolus
LS	0005737	cellular_component	cytoplasm
LS	0005829	cellular_component	cytosol
LS	0005840	cellular_component	ribosome
LS	0006412	biological_process	translation
LS	0016020	cellular_component	membrane
LS	0022625	cellular_component	cytosolic large ribosomal subunit
LS	0022626	cellular_component	cytosolic ribosome
LS	1990904	cellular_component	ribonucleoprotein complex
LT	0000049	molecular_function	tRNA binding
LT	0002181	biological_process	cytoplasmic translation
LT	0003723	molecular_function	RNA binding
LT	0003735	molecular_function	structural constituent of ribosome
LT	0005515	molecular_function	protein binding
LT	0005737	cellular_component	cytoplasm
LT	0005829	cellular_component	cytosol
LT	0005840	cellular_component	ribosome
LT	0006364	biological_process	rRNA processing
LT	0006412	biological_process	translation
LT	0016020	cellular_component	membrane
LT	0022625	cellular_component	cytosolic large ribosomal subunit
LT	0022626	cellular_component	cytosolic ribosome
LT	0042273	biological_process	ribosomal large subunit biogenesis
LT	0070062	cellular_component	extracellular exosome
LT	1990904	cellular_component	ribonucleoprotein complex
LU	0002181	biological_process	cytoplasmic translation
LU	0003723	molecular_function	RNA binding
LU	0003735	molecular_function	structural constituent of ribosome
LU	0005515	molecular_function	protein binding
LU	0005730	cellular_component	nucleolus
LU	0005737	cellular_component	cytoplasm
LU	0005829	cellular_component	cytosol
LU	0005840	cellular_component	ribosome
LU	0006412	biological_process	translation
LU	0016020	cellular_component	membrane
LU	0022625	cellular_component	cytosolic large ribosomal subunit
LU	0022626	cellular_component	cytosolic ribosome
LU	0045202	cellular_component	synapse
LU	1990904	cellular_component	ribonucleoprotein complex
LV	0002181	biological_process	cytoplasmic translation
LV	0003723	molecular_function	RNA binding
LV	0003735	molecular_function	structural constituent of ribosome
LV	0005515	molecular_function	protein binding
LV	0005737	cellular_component	cytoplasm
LV	0005783	cellular_component	endoplasmic reticulum
LV	0005829	cellular_component	cytosol
LV	0005840	cellular_component	ribosome
LV	0005886	cellular_component	plasma membrane
LV	0006412	biological_process	translation
LV	0022625	cellular_component	cytosolic large ribosomal subunit
LV	0022626	cellular_component	cytosolic ribosome
LV	1990904	cellular_component	ribonucleoprotein complex
LW	0002181	biological_process	cytoplasmic translation
LW	0003723	molecular_function	RNA binding
LW	0003735	molecular_function	structural constituent of ribosome
LW	0005737	cellular_component	cytoplasm
LW	0005829	cellular_component	cytosol
LW	0005840	cellular_component	ribosome
LW	0006412	biological_process	translation
LW	0019843	molecular_function	rRNA binding
LW	0022625	cellular_component	cytosolic large ribosomal subunit
LW	0022626	cellular_component	cytosolic ribosome
LW	0046872	molecular_function	metal ion binding
LW	0097371	molecular_function	MDM2/MDM4 family protein binding
LW	1901798	biological_process	positive regulation of signal transduction by p53 class mediator
LW	1990904	cellular_component	ribonucleoprotein complex
LW	1990948	molecular_function	ubiquitin ligase inhibitor activity
LX	0002181	biological_process	cytoplasmic translation
LX	0003723	molecular_function	RNA binding
LX	0003735	molecular_function	structural constituent of ribosome
LX	0005515	molecular_function	protein binding
LX	0005634	cellular_component	nucleus
LX	0005737	cellular_component	cytoplasm
LX	0005829	cellular_component	cytosol
LX	0005840	cellular_component	ribosome
LX	0005925	cellular_component	focal adhesion
LX	0006412	biological_process	translation
LX	0022625	cellular_component	cytosolic large ribosomal subunit
LX	0022626	cellular_component	cytosolic ribosome
LX	0046872	molecular_function	metal ion binding
LX	0070062	cellular_component	extracellular exosome
LX	1990904	cellular_component	ribonucleoprotein complex
LY	0001501	biological_process	skeletal system development
LY	0001503	biological_process	ossification
LY	0002181	biological_process	cytoplasmic translation
LY	0003723	molecular_function	RNA binding
LY	0003735	molecular_function	structural constituent of ribosome
LY	0005515	molecular_function	protein binding
LY	0005737	cellular_component	cytoplasm
LY	0005829	cellular_component	cytosol
LY	0005840	cellular_component	ribosome
LY	0005925	cellular_component	focal adhesion
LY	0006412	biological_process	translation
LY	0006417	biological_process	regulation of translation
LY	0007605	biological_process	sensory perception of sound
LY	0014069	cellular_component	postsynaptic density
LY	0022618	biological_process	protein-RNA complex assembly
LY	0022625	cellular_component	cytosolic large ribosomal subunit
LY	0022626	cellular_component	cytosolic ribosome
LY	0033291	cellular_component	eukaryotic 80S initiation complex
LY	0034463	biological_process	90S preribosome assembly
LY	0042474	biological_process	middle ear morphogenesis
LY	0045202	cellular_component	synapse
LY	0048318	biological_process	axial mesoderm development
LY	1990904	cellular_component	ribonucleoprotein complex
LZ	0002181	biological_process	cytoplasmic translation
LZ	0002227	biological_process	innate immune response in mucosa
LZ	0003723	molecular_function	RNA binding
LZ	0003735	molecular_function	structural constituent of ribosome
LZ	0005615	cellular_component	extracellular space
LZ	0005737	cellular_component	cytoplasm
LZ	0005829	cellular_component	cytosol
LZ	0005840	cellular_component	ribosome
LZ	0006412	biological_process	translation
LZ	0019731	biological_process	antibacterial humoral response
LZ	0022625	cellular_component	cytosolic large ribosomal subunit
LZ	0022626	cellular_component	cytosolic ribosome
LZ	0050830	biological_process	defense response to Gram-positive bacterium
LZ	0061844	biological_process	antimicrobial humoral immune response mediated by antimicrobial peptide
LZ	1990904	cellular_component	ribonucleoprotein complex
NK	0001099	molecular_function	basal RNA polymerase II transcription machinery binding
NK	0003723	molecular_function	RNA binding
NK	0005515	molecular_function	protein binding
NK	0005634	cellular_component	nucleus
NK	0005694	cellular_component	chromosome
NK	0005730	cellular_component	nucleolus
NK	0060999	biological_process	positive regulation of dendritic spine development
NK	0097484	biological_process	dendrite extension
NL	0000027	biological_process	ribosomal large subunit assembly
NL	0000122	biological_process	negative regulation of transcription by RNA polymerase II
NL	0001650	cellular_component	fibrillar center
NL	0001932	biological_process	regulation of protein phosphorylation
NL	0002039	molecular_function	p53 binding
NL	0003723	molecular_function	RNA binding
NL	0005515	molecular_function	protein binding
NL	0005634	cellular_component	nucleus
NL	0005654	cellular_component	nucleoplasm
NL	0005730	cellular_component	nucleolus
NL	0005829	cellular_component	cytosol
NL	0006281	biological_process	DNA repair
NL	0006364	biological_process	rRNA processing
NL	0006974	biological_process	DNA damage response
NL	0007095	biological_process	mitotic G2 DNA damage checkpoint signaling
NL	0008097	molecular_function	5S rRNA binding
NL	0031333	biological_process	negative regulation of protein-containing complex assembly
NL	0032435	biological_process	negative regulation of proteasomal ubiquitin-dependent protein catabolic process
NL	0032436	biological_process	positive regulation of proteasomal ubiquitin-dependent protein catabolic process
NL	0033553	cellular_component	rDNA heterochromatin
NL	0039535	biological_process	regulation of RIG-I signaling pathway
NL	0042254	biological_process	ribosome biogenesis
NL	0042802	molecular_function	identical protein binding
NL	0042981	biological_process	regulation of apoptotic process
NL	0043231	cellular_component	intracellular membrane-bounded organelle
NL	0050821	biological_process	protein stabilization
NL	0051726	biological_process	regulation of cell cycle
NL	0051898	biological_process	negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
NL	0071456	biological_process	cellular response to hypoxia
NL	1901796	biological_process	regulation of signal transduction by p53 class mediator
NL	1901797	biological_process	negative regulation of signal transduction by p53 class mediator
NL	1901837	biological_process	negative regulation of transcription of nucleolar large rRNA by RNA polymerase I
NL	1902570	biological_process	protein localization to nucleolus
NL	1903006	biological_process	positive regulation of protein K63-linked deubiquitination
NL	1903715	biological_process	regulation of aerobic respiration
NL	1990173	biological_process	protein localization to nucleoplasm
NP	0003676	molecular_function	nucleic acid binding
NP	0003677	molecular_function	DNA binding
NP	0005515	molecular_function	protein binding
NP	0005634	cellular_component	nucleus
NP	0005654	cellular_component	nucleoplasm
NP	0005730	cellular_component	nucleolus
NP	0005737	cellular_component	cytoplasm
NP	0008270	molecular_function	zinc ion binding
NP	0042254	biological_process	ribosome biogenesis
NP	0045944	biological_process	positive regulation of transcription by RNA polymerase II
NP	0046872	molecular_function	metal ion binding
NP	1903026	biological_process	negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding
NP	1990275	molecular_function	preribosome binding
SA	0002181	biological_process	cytoplasmic translation
SA	0003723	molecular_function	RNA binding
SA	0003735	molecular_function	structural constituent of ribosome
SA	0005515	molecular_function	protein binding
SA	0005634	cellular_component	nucleus
SA	0005730	cellular_component	nucleolus
SA	0005737	cellular_component	cytoplasm
SA	0005791	cellular_component	rough endoplasmic reticulum
SA	0005829	cellular_component	cytosol
SA	0005840	cellular_component	ribosome
SA	0005925	cellular_component	focal adhesion
SA	0006412	biological_process	translation
SA	0016020	cellular_component	membrane
SA	0022625	cellular_component	cytosolic large ribosomal subunit
SA	0022626	cellular_component	cytosolic ribosome
SA	0070062	cellular_component	extracellular exosome
SA	1990904	cellular_component	ribonucleoprotein complex
SB	0000027	biological_process	ribosomal large subunit assembly
SB	0002181	biological_process	cytoplasmic translation
SB	0003723	molecular_function	RNA binding
SB	0003730	molecular_function	mRNA 3'-UTR binding
SB	0003735	molecular_function	structural constituent of ribosome
SB	0005515	molecular_function	protein binding
SB	0005634	cellular_component	nucleus
SB	0005654	cellular_component	nucleoplasm
SB	0005730	cellular_component	nucleolus
SB	0005737	cellular_component	cytoplasm
SB	0005783	cellular_component	endoplasmic reticulum
SB	0005829	cellular_component	cytosol
SB	0005840	cellular_component	ribosome
SB	0005925	cellular_component	focal adhesion
SB	0006364	biological_process	rRNA processing
SB	0006412	biological_process	translation
SB	0008097	molecular_function	5S rRNA binding
SB	0010628	biological_process	positive regulation of gene expression
SB	0016020	cellular_component	membrane
SB	0019843	molecular_function	rRNA binding
SB	0022625	cellular_component	cytosolic large ribosomal subunit
SB	0022626	cellular_component	cytosolic ribosome
SB	0031625	molecular_function	ubiquitin protein ligase binding
SB	0032991	cellular_component	protein-containing complex
SB	0042273	biological_process	ribosomal large subunit biogenesis
SB	0045727	biological_process	positive regulation of translation
SB	0048027	molecular_function	mRNA 5'-UTR binding
SB	0050821	biological_process	protein stabilization
SB	0070062	cellular_component	extracellular exosome
SB	1901796	biological_process	regulation of signal transduction by p53 class mediator
SB	1904667	biological_process	negative regulation of ubiquitin protein ligase activity
SB	1990904	cellular_component	ribonucleoprotein complex
SB	1990948	molecular_function	ubiquitin ligase inhibitor activity
SB	2000059	biological_process	negative regulation of ubiquitin-dependent protein catabolic process
SB	2000435	biological_process	negative regulation of protein neddylation
SC	0000027	biological_process	ribosomal large subunit assembly
SC	0002181	biological_process	cytoplasmic translation
SC	0003677	molecular_function	DNA binding
SC	0003723	molecular_function	RNA binding
SC	0003735	molecular_function	structural constituent of ribosome
SC	0005515	molecular_function	protein binding
SC	0005634	cellular_component	nucleus
SC	0005737	cellular_component	cytoplasm
SC	0005783	cellular_component	endoplasmic reticulum
SC	0005791	cellular_component	rough endoplasmic reticulum
SC	0005829	cellular_component	cytosol
SC	0005840	cellular_component	ribosome
SC	0005925	cellular_component	focal adhesion
SC	0006355	biological_process	regulation of DNA-templated transcription
SC	0006412	biological_process	translation
SC	0014069	cellular_component	postsynaptic density
SC	0016020	cellular_component	membrane
SC	0022625	cellular_component	cytosolic large ribosomal subunit
SC	0022626	cellular_component	cytosolic ribosome
SC	0036464	cellular_component	cytoplasmic ribonucleoprotein granule
SC	0045202	cellular_component	synapse
SC	0045296	molecular_function	cadherin binding
SC	1990904	cellular_component	ribonucleoprotein complex
SD	0000463	biological_process	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
SD	0002181	biological_process	cytoplasmic translation
SD	0003677	molecular_function	DNA binding
SD	0003723	molecular_function	RNA binding
SD	0003729	molecular_function	mRNA binding
SD	0003735	molecular_function	structural constituent of ribosome
SD	0005515	molecular_function	protein binding
SD	0005634	cellular_component	nucleus
SD	0005730	cellular_component	nucleolus
SD	0005737	cellular_component	cytoplasm
SD	0005829	cellular_component	cytosol
SD	0005840	cellular_component	ribosome
SD	0005925	cellular_component	focal adhesion
SD	0006364	biological_process	rRNA processing
SD	0006412	biological_process	translation
SD	0014069	cellular_component	postsynaptic density
SD	0016020	cellular_component	membrane
SD	0022625	cellular_component	cytosolic large ribosomal subunit
SD	0022626	cellular_component	cytosolic ribosome
SD	0042273	biological_process	ribosomal large subunit biogenesis
SD	0042802	molecular_function	identical protein binding
SD	1990904	cellular_component	ribonucleoprotein complex
SE	0000470	biological_process	maturation of LSU-rRNA
SE	0002181	biological_process	cytoplasmic translation
SE	0003723	molecular_function	RNA binding
SE	0003735	molecular_function	structural constituent of ribosome
SE	0005515	molecular_function	protein binding
SE	0005634	cellular_component	nucleus
SE	0005730	cellular_component	nucleolus
SE	0005737	cellular_component	cytoplasm
SE	0005829	cellular_component	cytosol
SE	0005840	cellular_component	ribosome
SE	0005925	cellular_component	focal adhesion
SE	0006412	biological_process	translation
SE	0016020	cellular_component	membrane
SE	0022625	cellular_component	cytosolic large ribosomal subunit
SE	0022626	cellular_component	cytosolic ribosome
SE	0042254	biological_process	ribosome biogenesis
SE	0045202	cellular_component	synapse
SE	0045296	molecular_function	cadherin binding
SE	1990904	cellular_component	ribonucleoprotein complex
SF	0002181	biological_process	cytoplasmic translation
SF	0003723	molecular_function	RNA binding
SF	0003735	molecular_function	structural constituent of ribosome
SF	0005515	molecular_function	protein binding
SF	0005654	cellular_component	nucleoplasm
SF	0005737	cellular_component	cytoplasm
SF	0005829	cellular_component	cytosol
SF	0005840	cellular_component	ribosome
SF	0005925	cellular_component	focal adhesion
SF	0006412	biological_process	translation
SF	0014069	cellular_component	postsynaptic density
SF	0015934	cellular_component	large ribosomal subunit
SF	0016020	cellular_component	membrane
SF	0019843	molecular_function	rRNA binding
SF	0022625	cellular_component	cytosolic large ribosomal subunit
SF	0022626	cellular_component	cytosolic ribosome
SF	0045202	cellular_component	synapse
SF	0098794	cellular_component	postsynapse
SF	1990904	cellular_component	ribonucleoprotein complex
SG	0002181	biological_process	cytoplasmic translation
SG	0003723	molecular_function	RNA binding
SG	0003735	molecular_function	structural constituent of ribosome
SG	0005515	molecular_function	protein binding
SG	0005634	cellular_component	nucleus
SG	0005737	cellular_component	cytoplasm
SG	0005829	cellular_component	cytosol
SG	0005840	cellular_component	ribosome
SG	0005925	cellular_component	focal adhesion
SG	0006412	biological_process	translation
SG	0016020	cellular_component	membrane
SG	0019843	molecular_function	rRNA binding
SG	0022625	cellular_component	cytosolic large ribosomal subunit
SG	0022626	cellular_component	cytosolic ribosome
SG	1990904	cellular_component	ribonucleoprotein complex
SH	0000463	biological_process	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
SH	0000794	cellular_component	condensed nuclear chromosome
SH	0003676	molecular_function	nucleic acid binding
SH	0003723	molecular_function	RNA binding
SH	0005515	molecular_function	protein binding
SH	0005634	cellular_component	nucleus
SH	0005654	cellular_component	nucleoplasm
SH	0005694	cellular_component	chromosome
SH	0005730	cellular_component	nucleolus
SH	0005737	cellular_component	cytoplasm
SH	0009303	biological_process	rRNA transcription
SH	0016072	biological_process	rRNA metabolic process
SH	0065003	biological_process	protein-containing complex assembly
SI	0000463	biological_process	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
SI	0001825	biological_process	blastocyst formation
SI	0003723	molecular_function	RNA binding
SI	0003735	molecular_function	structural constituent of ribosome
SI	0005515	molecular_function	protein binding
SI	0005730	cellular_component	nucleolus
SI	0005739	cellular_component	mitochondrion
SI	0005840	cellular_component	ribosome
SI	0022625	cellular_component	cytosolic large ribosomal subunit
SI	1990904	cellular_component	ribonucleoprotein complex
SK	0000054	biological_process	ribosomal subunit export from nucleus
SK	0000460	biological_process	maturation of 5.8S rRNA
SK	0000470	biological_process	maturation of LSU-rRNA
SK	0003743	molecular_function	translation initiation factor activity
SK	0005515	molecular_function	protein binding
SK	0005634	cellular_component	nucleus
SK	0005638	cellular_component	lamin filament
SK	0005654	cellular_component	nucleoplasm
SK	0005730	cellular_component	nucleolus
SK	0005737	cellular_component	cytoplasm
SK	0005829	cellular_component	cytosol
SK	0005882	cellular_component	intermediate filament
SK	0006110	biological_process	regulation of glycolytic process
SK	0006412	biological_process	translation
SK	0006413	biological_process	translational initiation
SK	0030687	cellular_component	preribosome, large subunit precursor
SK	0032868	biological_process	response to insulin
SK	0035195	biological_process	miRNA-mediated post-transcriptional gene silencing
SK	0035278	biological_process	miRNA-mediated gene silencing by inhibition of translation
SK	0042254	biological_process	ribosome biogenesis
SK	0042256	biological_process	cytosolic ribosome assembly
SK	0042273	biological_process	ribosomal large subunit biogenesis
SK	0042304	biological_process	regulation of fatty acid biosynthetic process
SK	0043022	molecular_function	ribosome binding
SK	0043023	molecular_function	ribosomal large subunit binding
SK	0045202	cellular_component	synapse
SK	0045652	biological_process	regulation of megakaryocyte differentiation
SK	0045727	biological_process	positive regulation of translation
SK	0070062	cellular_component	extracellular exosome
SK	1902626	biological_process	assembly of large subunit precursor of preribosome
SK	2000377	biological_process	regulation of reactive oxygen species metabolic process
SM	0000463	biological_process	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
SM	0000466	biological_process	maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
SM	0003723	molecular_function	RNA binding
SM	0005515	molecular_function	protein binding
SM	0005634	cellular_component	nucleus
SM	0005654	cellular_component	nucleoplasm
SM	0005694	cellular_component	chromosome
SM	0005730	cellular_component	nucleolus
SM	0005829	cellular_component	cytosol
SM	0006364	biological_process	rRNA processing
SM	0008283	biological_process	cell population proliferation
SM	0016020	cellular_component	membrane
SM	0030687	cellular_component	preribosome, large subunit precursor
SM	0042254	biological_process	ribosome biogenesis
SM	0042273	biological_process	ribosomal large subunit biogenesis
SM	0043021	molecular_function	ribonucleoprotein complex binding
SM	0051726	biological_process	regulation of cell cycle
SM	0070545	cellular_component	PeBoW complex
SQ	0000027	biological_process	ribosomal large subunit assembly
SQ	0000956	biological_process	nuclear-transcribed mRNA catabolic process
SQ	0003723	molecular_function	RNA binding
SQ	0005515	molecular_function	protein binding
SQ	0005634	cellular_component	nucleus
SQ	0005730	cellular_component	nucleolus
SQ	0005737	cellular_component	cytoplasm
SQ	0006364	biological_process	rRNA processing
SQ	0030687	cellular_component	preribosome, large subunit precursor
SQ	0042254	biological_process	ribosome biogenesis
SQ	0042273	biological_process	ribosomal large subunit biogenesis
SR	0000079	biological_process	regulation of cyclin-dependent protein serine/threonine kinase activity
SR	0000463	biological_process	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
SR	0001649	biological_process	osteoblast differentiation
SR	0003723	molecular_function	RNA binding
SR	0003924	molecular_function	GTPase activity
SR	0005515	molecular_function	protein binding
SR	0005525	molecular_function	GTP binding
SR	0005634	cellular_component	nucleus
SR	0005654	cellular_component	nucleoplasm
SR	0005730	cellular_component	nucleolus
SR	0005737	cellular_component	cytoplasm
SR	0005829	cellular_component	cytosol
SR	0008156	biological_process	negative regulation of DNA replication
SR	0008285	biological_process	negative regulation of cell population proliferation
SR	0016020	cellular_component	membrane
SR	0022408	biological_process	negative regulation of cell-cell adhesion
SR	0030336	biological_process	negative regulation of cell migration
SR	0031397	biological_process	negative regulation of protein ubiquitination
SR	0031965	cellular_component	nuclear membrane
SR	0033342	biological_process	negative regulation of collagen binding
SR	0042254	biological_process	ribosome biogenesis
SR	0042273	biological_process	ribosomal large subunit biogenesis
SR	0048471	cellular_component	perinuclear region of cytoplasm
SR	0050821	biological_process	protein stabilization
SR	1990275	molecular_function	preribosome binding
SV	0003735	molecular_function	structural constituent of ribosome
SV	0005515	molecular_function	protein binding
SV	0005634	cellular_component	nucleus
SV	0005654	cellular_component	nucleoplasm
SV	0005730	cellular_component	nucleolus
SV	0005840	cellular_component	ribosome
SV	0006412	biological_process	translation
SV	0042254	biological_process	ribosome biogenesis
SV	0042273	biological_process	ribosomal large subunit biogenesis

Functional Information from PROSITE/UniProt

site_id	PS00028
Number of Residues	23
Details	ZINC_FINGER_C2H2_1 Zinc finger C2H2 type domain signature. Cla..CaryFidstnlktHfrskdH

Chain	Residue	Details
NP	CYS63-HIS85

site_id	PS00049
Number of Residues	27
Details	RIBOSOMAL_L14 Ribosomal protein L14 signature. AVVIrqrksyrrk.DGvflyFedNagVI

Chain	Residue	Details
LG	ALA79-ILE105

site_id	PS00050
Number of Residues	16
Details	RIBOSOMAL_L23 Ribosomal protein L23 signature. KKAYVRLApdydaldV

Chain	Residue	Details
LH	LYS134-VAL149

site_id	PS00051
Number of Residues	17
Details	RIBOSOMAL_L39E Ribosomal protein L39e signature. KTgnkIryNskrRHWRR

Chain	Residue	Details
LZ	LYS30-ARG46

site_id	PS00071
Number of Residues	8
Details	GAPDH Glyceraldehyde 3-phosphate dehydrogenase active site. SSCTTRkM

Chain	Residue	Details
SI	SER3-MET10

site_id	PS00358
Number of Residues	17
Details	RIBOSOMAL_L5 Ribosomal protein L5 signature. LeqLTGQtpVfSkARyT

Chain	Residue	Details
L5	LEU40-THR56

site_id	PS00464
Number of Residues	25
Details	RIBOSOMAL_L22 Ribosomal protein L22 signature. RrrTyRAhGRinpymsspCHIEMiL

Chain	Residue	Details
LA	ARG126-LEU150

site_id	PS00467
Number of Residues	12
Details	RIBOSOMAL_L2 Ribosomal protein L2 signature. PrvRGVAmNPvE

Chain	Residue	Details
SF	PRO197-GLU208

site_id	PS00474
Number of Residues	24
Details	RIBOSOMAL_L3 Ribosomal protein L3 signature. FgqdemiDviGvTkGKGykGvtsR

Chain	Residue	Details
LN	PHE211-ARG234

site_id	PS00475
Number of Residues	32
Details	RIBOSOMAL_L15 Ribosomal protein L15 signature. KVLGkGkLpkqp.ViVkakfFSrrAeekIksvG

Chain	Residue	Details
LK	LYS110-GLY141

site_id	PS00526
Number of Residues	20
Details	RIBOSOMAL_L19E Ribosomal protein L19e signature. QKRLaSsvlrCGkkkVWLDP

Chain	Residue	Details
LD	GLN7-PRO26

site_id	PS00579
Number of Residues	15
Details	RIBOSOMAL_L29 Ribosomal protein L29 signature. KLSKIRvVRKSIARV

Chain	Residue	Details
LS	LYS43-VAL57

site_id	PS00580
Number of Residues	21
Details	RIBOSOMAL_L32E Ribosomal protein L32e signature. FiRhqsdRyvKIkrn..WRKprG

Chain	Residue	Details
LQ	PHE20-GLY40

site_id	PS00634
Number of Residues	33
Details	RIBOSOMAL_L30 Ribosomal protein L30 signature. TIarLrLkKifSgVfvkvtpqnlkMLriVepYV

Chain	Residue	Details
SI	THR115-VAL147
SD	VAL108-ILE140

site_id	PS00687
Number of Residues	8
Details	ALDEHYDE_DEHYDR_GLU Aldehyde dehydrogenases glutamic acid active site. GESSGKNV

Chain	Residue	Details
SA	GLY15-VAL22

site_id	PS00700
Number of Residues	22
Details	RIBOSOMAL_L6_2 Ribosomal protein L6 signature 2. QattVknKdiRkFlDGIYVseK

Chain	Residue	Details
SG	GLN163-LYS184

site_id	PS00709
Number of Residues	25
Details	RIBOSOMAL_L30E_1 Ribosomal protein L30e signature 1. SgkyvlGyKqtLKmiRqGkaKlVIL

Chain	Residue	Details
LO	SER24-LEU48

site_id	PS00783
Number of Residues	24
Details	RIBOSOMAL_L13 Ribosomal protein L13 signature. VRGMLPhktkrGQaaldrLkVFdG

Chain	Residue	Details
L7	VAL84-GLY107

site_id	PS00939
Number of Residues	27
Details	RIBOSOMAL_L1E Ribosomal protein L1e signature. NttqKryAIcSALaASAlpalvmsKGH

Chain	Residue	Details
SA	ASN116-HIS142

site_id	PS00993
Number of Residues	21
Details	RIBOSOMAL_L30E_2 Ribosomal protein L30e signature 2. ELGTacGKyyrvctLaIiDpG

Chain	Residue	Details
LO	GLU80-GLY100

site_id	PS01073
Number of Residues	18
Details	RIBOSOMAL_L24E Ribosomal protein L24e signature. FcSgpIyPGhGmmFvRnD

Chain	Residue	Details
SV	PHE8-ASP25

site_id	PS01077
Number of Residues	20
Details	RIBOSOMAL_L37E Ribosomal protein L37e signature. GTsSfGkRrnkt.HtlCrRCG

Chain	Residue	Details
LW	GLY4-GLY23

site_id	PS01082
Number of Residues	18
Details	RIBOSOMAL_L7AE Ribosomal protein L7Ae signature. CrkmgVPYciIkGKarLG

Chain	Residue	Details
SE	CYS174-GLY191

site_id	PS01104
Number of Residues	15
Details	RIBOSOMAL_L13E Ribosomal protein L13e signature. RaGRGFSLeELrvaG

Chain	Residue	Details
L6	ARG71-GLY85

site_id	PS01105
Number of Residues	22
Details	RIBOSOMAL_L35AE Ribosomal protein L35Ae signature. GKVtRaHGnsGmVrAkFrsnLP

Chain	Residue	Details
LT	GLY72-PRO93

site_id	PS01106
Number of Residues	18
Details	RIBOSOMAL_L18E Ribosomal protein L18e signature. KrLfmSRtnRPpLSLsRM

Chain	Residue	Details
LB	LYS49-MET66

site_id	PS01107
Number of Residues	12
Details	RIBOSOMAL_L27E Ribosomal protein L27e signature. GKNkWFFqkLRF

Chain	Residue	Details
LJ	GLY125-PHE136

site_id	PS01108
Number of Residues	19
Details	RIBOSOMAL_L24 Ribosomal protein L24 signature. DDeVqVVrGhyKGqqiGkV

Chain	Residue	Details
LI	ASP52-VAL70

site_id	PS01144
Number of Residues	15
Details	RIBOSOMAL_L31E Ribosomal protein L31e signature. VRIDtrLNkAvWaKG

Chain	Residue	Details
LP	VAL62-GLY76

site_id	PS01145
Number of Residues	14
Details	RIBOSOMAL_L34E Ribosomal protein L34e signature. TaSnKtrlsRTPGN

Chain	Residue	Details
LR	THR15-ASN28

site_id	PS01170
Number of Residues	19
Details	RIBOSOMAL_L6E Ribosomal protein L6e signature. NrvPLRRthqkFVIATSt.K

Chain	Residue	Details
SC	ASN182-LYS200

site_id	PS01171
Number of Residues	26
Details	RIBOSOMAL_L21E Ribosomal protein L21e signature. GDiVdikgmgtvqk.GmpHkcYhGkTG

Chain	Residue	Details
LE	GLY37-GLY62

site_id	PS01172
Number of Residues	12
Details	RIBOSOMAL_L44E Ribosomal protein L44e signature. KtTKKivLRleC

Chain	Residue	Details
LV	LYS61-CYS72

site_id	PS01190
Number of Residues	11
Details	RIBOSOMAL_L36E Ribosomal protein L36e signature. PYERRaMELLK

Chain	Residue	Details
LU	PRO52-LYS62

site_id	PS01194
Number of Residues	24
Details	RIBOSOMAL_L15E Ribosomal protein L15e signature. DKARrLGYkAkqGYVIYRiRVrRG

Chain	Residue	Details
L9	ASP46-GLY69

site_id	PS01257
Number of Residues	22
Details	RIBOSOMAL_L10E Ribosomal protein L10e signature. ADRlqtGMRgAFGKPqGtvARV

Chain	Residue	Details
BE	ALA108-VAL129

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0000250\|UniProtKB:P61314

Chain	Residue	Details
L9	SER34
SR	ASP221
SR	ASN289

site_id	SWS_FT_FI2
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744\|PubMed:18669648, ECO:0007744\|PubMed:21406692, ECO:0007744\|PubMed:23186163

Chain	Residue	Details
L9	SER97
L7	ARG140
SF	LYS149
SF	LYS234
SF	LYS250

site_id	SWS_FT_FI3
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744\|PubMed:19369195

Chain	Residue	Details
L9	SER100
LP	LYS70
SE	LYS20
SE	LYS21
SE	LYS48
SE	LYS125
SE	LYS245

site_id	SWS_FT_FI4
Number of Residues	1
Details	LIPID: N-myristoyl glycine => ECO:0000269\|PubMed:25255805

Chain	Residue	Details
L9	GLY2
SK	SER175

site_id	SWS_FT_FI5
Number of Residues	2
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744\|PubMed:28112733

Chain	Residue	Details
L9	LYS83
SR	SER470

site_id	SWS_FT_FI6
Number of Residues	2
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744\|PubMed:28112733

Chain	Residue	Details
L6	LYS123
L6	LYS145
L5	LYS154

site_id	SWS_FT_FI7
Number of Residues	3
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternate => ECO:0007744\|PubMed:28112733

Chain	Residue	Details
SR	LYS522
L6	LYS174
L6	LYS177
LN	LYS386
LN	LYS393

site_id	SWS_FT_FI8
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744\|PubMed:18669648

Chain	Residue	Details
SR	SER558
LN	LYS399

site_id	SWS_FT_FI9
Number of Residues	1
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternate => ECO:0007744\|PubMed:28112733

Chain	Residue	Details
SR	LYS103
SH	ARG245

site_id	SWS_FT_FI10
Number of Residues	3
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744\|PubMed:28112733

Chain	Residue	Details
SH	SER247
SR	LYS332
SR	LYS534

site_id	SWS_FT_FI11
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744\|PubMed:18669648

Chain	Residue	Details
SH	THR279
SA	LYS327

site_id	SWS_FT_FI12
Number of Residues	4
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744\|PubMed:28112733

Chain	Residue	Details
SH	LYS38
SH	LYS139
SH	LYS179
SH	LYS192

site_id	SWS_FT_FI13
Number of Residues	2
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternate => ECO:0007744\|PubMed:28112733

Chain	Residue	Details
SH	LYS271

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		Validation report (PDF)