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8FFZ

TFIIIA-TFIIIC-Brf1-TBP complex bound to 5S rRNA gene

Functional Information from GO Data
ChainGOidnamespacecontents
A0000978molecular_functionRNA polymerase II cis-regulatory region sequence-specific DNA binding
A0000981molecular_functionDNA-binding transcription factor activity, RNA polymerase II-specific
A0001002molecular_functionRNA polymerase III type 1 promoter sequence-specific DNA binding
A0001010molecular_functionRNA polymerase II sequence-specific DNA-binding transcription factor recruiting activity
A0003677molecular_functionDNA binding
A0003723molecular_functionRNA binding
A0005634cellular_componentnucleus
A0005654cellular_componentnucleoplasm
A0006355biological_processregulation of DNA-templated transcription
A0006357biological_processregulation of transcription by RNA polymerase II
A0008270molecular_functionzinc ion binding
A0042791biological_process5S class rRNA transcription by RNA polymerase III
A0046872molecular_functionmetal ion binding
B0000127cellular_componenttranscription factor TFIIIC complex
B0001002molecular_functionRNA polymerase III type 1 promoter sequence-specific DNA binding
B0001003molecular_functionRNA polymerase III type 2 promoter sequence-specific DNA binding
B0003677molecular_functionDNA binding
B0005634cellular_componentnucleus
B0005654cellular_componentnucleoplasm
B0005739cellular_componentmitochondrion
B0006383biological_processtranscription by RNA polymerase III
B0006384biological_processtranscription initiation at RNA polymerase III promoter
B0008301molecular_functionDNA binding, bending
B0042791biological_process5S class rRNA transcription by RNA polymerase III
B0071168biological_processprotein localization to chromatin
C0000127cellular_componenttranscription factor TFIIIC complex
C0001002molecular_functionRNA polymerase III type 1 promoter sequence-specific DNA binding
C0001003molecular_functionRNA polymerase III type 2 promoter sequence-specific DNA binding
C0003677molecular_functionDNA binding
C0005634cellular_componentnucleus
C0005654cellular_componentnucleoplasm
C0005737cellular_componentcytoplasm
C0006383biological_processtranscription by RNA polymerase III
C0006384biological_processtranscription initiation at RNA polymerase III promoter
C0008301molecular_functionDNA binding, bending
C0042791biological_process5S class rRNA transcription by RNA polymerase III
D0000127cellular_componenttranscription factor TFIIIC complex
D0001002molecular_functionRNA polymerase III type 1 promoter sequence-specific DNA binding
D0001003molecular_functionRNA polymerase III type 2 promoter sequence-specific DNA binding
D0003677molecular_functionDNA binding
D0005515molecular_functionprotein binding
D0005634cellular_componentnucleus
D0005654cellular_componentnucleoplasm
D0006383biological_processtranscription by RNA polymerase III
D0006384biological_processtranscription initiation at RNA polymerase III promoter
D0008301molecular_functionDNA binding, bending
D0042791biological_process5S class rRNA transcription by RNA polymerase III
E0000127cellular_componenttranscription factor TFIIIC complex
E0000995molecular_functionRNA polymerase III general transcription initiation factor activity
E0001002molecular_functionRNA polymerase III type 1 promoter sequence-specific DNA binding
E0001003molecular_functionRNA polymerase III type 2 promoter sequence-specific DNA binding
E0003677molecular_functionDNA binding
E0005634cellular_componentnucleus
E0006383biological_processtranscription by RNA polymerase III
E0006384biological_processtranscription initiation at RNA polymerase III promoter
E0042791biological_process5S class rRNA transcription by RNA polymerase III
F0000127cellular_componenttranscription factor TFIIIC complex
F0001002molecular_functionRNA polymerase III type 1 promoter sequence-specific DNA binding
F0001003molecular_functionRNA polymerase III type 2 promoter sequence-specific DNA binding
F0003677molecular_functionDNA binding
F0005515molecular_functionprotein binding
F0005634cellular_componentnucleus
F0006383biological_processtranscription by RNA polymerase III
F0006384biological_processtranscription initiation at RNA polymerase III promoter
F0008270molecular_functionzinc ion binding
F0008301molecular_functionDNA binding, bending
F0042791biological_process5S class rRNA transcription by RNA polymerase III
G0000127cellular_componenttranscription factor TFIIIC complex
G0000995molecular_functionRNA polymerase III general transcription initiation factor activity
G0001002molecular_functionRNA polymerase III type 1 promoter sequence-specific DNA binding
G0001003molecular_functionRNA polymerase III type 2 promoter sequence-specific DNA binding
G0003677molecular_functionDNA binding
G0005515molecular_functionprotein binding
G0005634cellular_componentnucleus
G0006383biological_processtranscription by RNA polymerase III
G0006384biological_processtranscription initiation at RNA polymerase III promoter
G0008301molecular_functionDNA binding, bending
G0016791molecular_functionphosphatase activity
G0042791biological_process5S class rRNA transcription by RNA polymerase III
H0003677molecular_functionDNA binding
H0006352biological_processDNA-templated transcription initiation
H0017025molecular_functionTBP-class protein binding
Functional Information from PROSITE/UniProt
site_idPS00028
Number of Residues24
DetailsZINC_FINGER_C2H2_1 Zinc finger C2H2 type domain signature. CdydgCdkaFtrpsilteHqlsv.H
ChainResidueDetails
ACYS51-HIS74
ACYS82-HIS102
ACYS110-HIS130
ACYS136-HIS159
ACYS165-HIS186
ACYS196-HIS219
ACYS224-HIS244
ACYS367-HIS389

site_idPS00351
Number of Residues50
DetailsTFIID Transcription factor TFIID repeat signature. YnPkrFaaVImRirePKttaLIFaSGKMvvtGAKseddsklAsrkyariI
ChainResidueDetails
HTYR420-ILE469
HTYR511-LEU560

site_idPS00782
Number of Residues16
DetailsTFIIB Transcription factor TFIIB repeat signature. GRrsqNVIASCLYVAC
ChainResidueDetails
HGLY119-CYS134
HGLY217-CYS232

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues32
DetailsZN_FING: TFIIB-type => ECO:0000255|PROSITE-ProRule:PRU00469
ChainResidueDetails
HMET1-GLU33

site_idSWS_FT_FI2
Number of Residues4
DetailsBINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00469
ChainResidueDetails
HCYS4
HCYS7
HCYS25
HCYS28

site_idSWS_FT_FI3
Number of Residues1
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:17287358, ECO:0007744|PubMed:19779198
ChainResidueDetails
HSER381

site_idSWS_FT_FI4
Number of Residues25
DetailsZN_FING: C2H2-type 4 => ECO:0000255|PROSITE-ProRule:PRU00042
ChainResidueDetails
APHE134-HIS159

site_idSWS_FT_FI5
Number of Residues23
DetailsZN_FING: C2H2-type 5 => ECO:0000255|PROSITE-ProRule:PRU00042
ChainResidueDetails
ALEU163-HIS186

site_idSWS_FT_FI6
Number of Residues25
DetailsZN_FING: C2H2-type 6 => ECO:0000255|PROSITE-ProRule:PRU00042
ChainResidueDetails
ATYR194-HIS219

site_idSWS_FT_FI7
Number of Residues22
DetailsZN_FING: C2H2-type 7 => ECO:0000255|PROSITE-ProRule:PRU00042
ChainResidueDetails
ALEU222-HIS244

site_idSWS_FT_FI8
Number of Residues24
DetailsZN_FING: C2H2-type 8 => ECO:0000255|PROSITE-ProRule:PRU00042
ChainResidueDetails
ATRP253-HIS277

site_idSWS_FT_FI9
Number of Residues24
DetailsZN_FING: C2H2-type 9 => ECO:0000255|PROSITE-ProRule:PRU00042
ChainResidueDetails
ATYR365-HIS389

223532

PDB entries from 2024-08-07

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