8FAY
Human MUTYH adenine glycosylase bound to DNA containing a transition state analog (1N) paired with d(8-oxo-G)
Functional Information from PROSITE/UniProt
| site_id | PS00764 |
| Number of Residues | 17 |
| Details | ENDONUCLEASE_III_1 Endonuclease III iron-sulfur binding region signature. CtpqRPLCsqCpveslC |
| Chain | Residue | Details |
| A | CYS290-CYS306 |
| site_id | PS01155 |
| Number of Residues | 31 |
| Details | ENDONUCLEASE_III_2 Endonuclease III family signature. GhMPrtaetLqqlLPGVGrytAgaiAsiAFG |
| Chain | Residue | Details |
| A | GLY199-GLY229 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | ACT_SITE: Proton donor/acceptor => ECO:0000250|UniProtKB:P83847 |
| Chain | Residue | Details |
| A | LEU159 | |
| D | LEU159 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 8 |
| Details | BINDING: BINDING => ECO:0000250 |
| Chain | Residue | Details |
| A | GLU315 | |
| A | SER322 | |
| A | GLY325 | |
| A | GLU331 | |
| D | GLU315 | |
| D | SER322 | |
| D | GLY325 | |
| D | GLU331 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | SITE: Transition state stabilizer => ECO:0000250|UniProtKB:P83847 |
| Chain | Residue | Details |
| A | GLN261 | |
| D | GLN261 |
