8FA1

Cryo-EM structure of the SARS-CoV-2 HR1HR2 fusion core complex with N969K mutation

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0008199	molecular_function	ferric iron binding
A	0016020	cellular_component	membrane
A	0016722	molecular_function	oxidoreductase activity, acting on metal ions
A	0019031	cellular_component	viral envelope
A	0019064	biological_process	fusion of virus membrane with host plasma membrane
A	0039654	biological_process	fusion of virus membrane with host endosome membrane
A	0046813	biological_process	receptor-mediated virion attachment to host cell
A	0046872	molecular_function	metal ion binding
A	0055036	cellular_component	virion membrane
A	0075509	biological_process	endocytosis involved in viral entry into host cell
B	0008199	molecular_function	ferric iron binding
B	0016020	cellular_component	membrane
B	0016722	molecular_function	oxidoreductase activity, acting on metal ions
B	0019031	cellular_component	viral envelope
B	0019064	biological_process	fusion of virus membrane with host plasma membrane
B	0039654	biological_process	fusion of virus membrane with host endosome membrane
B	0046813	biological_process	receptor-mediated virion attachment to host cell
B	0046872	molecular_function	metal ion binding
B	0055036	cellular_component	virion membrane
B	0075509	biological_process	endocytosis involved in viral entry into host cell
C	0008199	molecular_function	ferric iron binding
C	0016020	cellular_component	membrane
C	0016722	molecular_function	oxidoreductase activity, acting on metal ions
C	0019031	cellular_component	viral envelope
C	0019064	biological_process	fusion of virus membrane with host plasma membrane
C	0039654	biological_process	fusion of virus membrane with host endosome membrane
C	0046813	biological_process	receptor-mediated virion attachment to host cell
C	0046872	molecular_function	metal ion binding
C	0055036	cellular_component	virion membrane
C	0075509	biological_process	endocytosis involved in viral entry into host cell
D	0019064	biological_process	fusion of virus membrane with host plasma membrane
D	0039654	biological_process	fusion of virus membrane with host endosome membrane
E	0019064	biological_process	fusion of virus membrane with host plasma membrane
E	0039654	biological_process	fusion of virus membrane with host endosome membrane
F	0019064	biological_process	fusion of virus membrane with host plasma membrane
F	0039654	biological_process	fusion of virus membrane with host endosome membrane

Functional Information from PROSITE/UniProt

site_id	PS00819
Number of Residues	15
Details	DPS_2 Dps protein family signature 2. IHeIGERldgLGgvP

Chain	Residue	Details
A	ILE814-PRO828

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	6
Details	CARBOHYD: N-linked (GlcNAc...) (complex) asparagine; by host => ECO:0000255|HAMAP-Rule:MF_04099, ECO:0000269|PubMed:32366695, ECO:0000269|PubMed:32979942

Chain	Residue	Details
D	ASN1158
D	ASN1173
E	ASN1158
E	ASN1173
F	ASN1158
F	ASN1173

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site_id	SWS_FT_FI2
Number of Residues	3
Details	CARBOHYD: N-linked (GlcNAc...) (complex) asparagine; by host => ECO:0000255|HAMAP-Rule:MF_04099, ECO:0000269|PubMed:32363391, ECO:0000269|PubMed:32366695, ECO:0000269|PubMed:32979942

Chain	Residue	Details
D	ASN1194
E	ASN1194
F	ASN1194

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