Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004725 | molecular_function | protein tyrosine phosphatase activity |
A | 0006470 | biological_process | protein dephosphorylation |
A | 0016311 | biological_process | dephosphorylation |
B | 0004725 | molecular_function | protein tyrosine phosphatase activity |
B | 0006470 | biological_process | protein dephosphorylation |
B | 0016311 | biological_process | dephosphorylation |
C | 0004725 | molecular_function | protein tyrosine phosphatase activity |
C | 0006470 | biological_process | protein dephosphorylation |
C | 0016311 | biological_process | dephosphorylation |
Functional Information from SwissProt/UniProt
Chain | Residue | Details |
E | TYR1162 | |
F | TYR1162 | |
G | TYR1162 | |
Chain | Residue | Details |
E | PTR1163 | |
F | PTR1163 | |
G | PTR1163 | |
site_id | SWS_FT_FI3 |
Number of Residues | 6 |
Details | BINDING: BINDING => ECO:0000250 |
Chain | Residue | Details |
A | ALA215 | |
A | ALA262 | |
B | ALA215 | |
B | ALA262 | |
C | ALA215 | |
C | ALA262 | |
Chain | Residue | Details |
A | MET1 | |
B | MET1 | |
C | MET1 | |
Chain | Residue | Details |
A | TYR20 | |
B | TYR20 | |
C | TYR20 | |
Chain | Residue | Details |
A | SER50 | |
B | SER50 | |
C | SER50 | |
Chain | Residue | Details |
A | TYR66 | |
B | TYR66 | |
C | TYR66 | |
site_id | SWS_FT_FI8 |
Number of Residues | 3 |
Details | MOD_RES: S-nitrosocysteine; in reversibly inhibited form => ECO:0000269|PubMed:22169477 |
Chain | Residue | Details |
A | ALA215 | |
B | ALA215 | |
C | ALA215 | |
Chain | Residue | Details |
A | SER242 | |
A | SER243 | |
B | SER242 | |
B | SER243 | |
C | SER242 | |
C | SER243 | |
Chain | Residue | Details |
A | ALA215 | |
A | SER216 | |
B | ALA215 | |
B | SER216 | |
C | ALA215 | |
C | SER216 | |
Catalytic Information from CSA
site_id | MCSA1 |
Number of Residues | 5 |
Details | M-CSA 469 |
Chain | Residue | Details |
A | ALA181 | proton shuttle (general acid/base) |
A | ALA215 | covalent catalysis |
A | ARG221 | activator, electrostatic stabiliser |
A | SER222 | activator, electrostatic stabiliser |
A | ALA262 | steric role |
site_id | MCSA2 |
Number of Residues | 5 |
Details | M-CSA 469 |
Chain | Residue | Details |
B | ALA181 | proton shuttle (general acid/base) |
B | ALA215 | covalent catalysis |
B | ARG221 | activator, electrostatic stabiliser |
B | SER222 | activator, electrostatic stabiliser |
B | ALA262 | steric role |
site_id | MCSA3 |
Number of Residues | 5 |
Details | M-CSA 469 |
Chain | Residue | Details |
C | ALA181 | proton shuttle (general acid/base) |
C | ALA215 | covalent catalysis |
C | ARG221 | activator, electrostatic stabiliser |
C | SER222 | activator, electrostatic stabiliser |
C | ALA262 | steric role |