8F38

Cryo-EM structure of X6 COBRA (H1N1) hemagglutinin bound to CR6261 Fab

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0019031	cellular_component	viral envelope
A	0019064	biological_process	fusion of virus membrane with host plasma membrane
A	0046789	molecular_function	host cell surface receptor binding
B	0019031	cellular_component	viral envelope
B	0019064	biological_process	fusion of virus membrane with host plasma membrane
B	0046789	molecular_function	host cell surface receptor binding
C	0019031	cellular_component	viral envelope
C	0019064	biological_process	fusion of virus membrane with host plasma membrane
C	0046789	molecular_function	host cell surface receptor binding

Functional Information from PROSITE/UniProt

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YICNVNH

Chain	Residue	Details
D	TYR202-HIS208
G	TYR200-HIS206

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1530
Details	TOPO_DOM: Extracellular => ECO:0000255|HAMAP-Rule:MF_04072

Chain	Residue	Details
A	ASP18-GLN528
B	ASP18-GLN528
C	ASP18-GLN528

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site_id	SWS_FT_FI2
Number of Residues	60
Details	TRANSMEM: Helical => ECO:0000255|HAMAP-Rule:MF_04072

Chain	Residue	Details
A	ILE529-ILE549
B	ILE529-ILE549
C	ILE529-ILE549

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site_id	SWS_FT_FI3
Number of Residues	45
Details	TOPO_DOM: Cytoplasmic => ECO:0000255|HAMAP-Rule:MF_04072

Chain	Residue	Details
A	SER550-ILE565
B	SER550-ILE565
C	SER550-ILE565

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site_id	SWS_FT_FI4
Number of Residues	3
Details	SITE: Cleavage; by host => ECO:0000255|HAMAP-Rule:MF_04072

Chain	Residue	Details
A	ARG343
B	ARG343
C	ARG343

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site_id	SWS_FT_FI5
Number of Residues	9
Details	LIPID: S-palmitoyl cysteine; by host => ECO:0000255|HAMAP-Rule:MF_04072

Chain	Residue	Details
A	CYS554
A	CYS561
A	CYS564
B	CYS554
B	CYS561
B	CYS564
C	CYS554
C	CYS561
C	CYS564

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site_id	SWS_FT_FI6
Number of Residues	27
Details	CARBOHYD: N-linked (GlcNAc...) asparagine; by host => ECO:0000255|HAMAP-Rule:MF_04072

Chain	Residue	Details
A	ASN27
B	ASN27
B	ASN28
B	ASN40
B	ASN71
B	ASN104
B	ASN142
B	ASN176
B	ASN303
B	ASN497
C	ASN27
A	ASN28
C	ASN28
C	ASN40
C	ASN71
C	ASN104
C	ASN142
C	ASN176
C	ASN303
C	ASN497
A	ASN40
A	ASN71
A	ASN104
A	ASN142
A	ASN176
A	ASN303
A	ASN497

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