8F2P

Nef SF2 dimerization mutant bound to Hck SH3

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005525	molecular_function	GTP binding

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	16
Details	Region: {"description":"Mediates dimerization, Nef-PTE1 interaction","evidences":[{"source":"HAMAP-Rule","id":"MF_04078","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	3
Details	Motif: {"description":"PxxP; stabilizes the interaction of NEF/MHC-I with host AP1M1; necessary for MHC-I internalization","evidences":[{"source":"HAMAP-Rule","id":"MF_04078","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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