8EXS

Cryo-EM structure of S. aureus BlaR1 F284A mutant

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005886	cellular_component	plasma membrane
A	0008658	molecular_function	penicillin binding
A	0071555	biological_process	cell wall organization
B	0005886	cellular_component	plasma membrane
B	0008658	molecular_function	penicillin binding
B	0071555	biological_process	cell wall organization

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	628
Details	TOPO_DOM: Extracellular => ECO:0000250|UniProtKB:P12287

Chain	Residue	Details
A	MET1-LEU4
A	PRO49-ASN104
A	LEU329-GLN585
B	MET1-LEU4
B	PRO49-ASN104
B	LEU329-GLN585

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site_id	SWS_FT_FI2
Number of Residues	132
Details	TRANSMEM: Helical => ECO:0000250|UniProtKB:P12287

Chain	Residue	Details
A	LEU5-PHE22
A	TYR32-ILE48
A	ILE105-LEU122
A	ILE312-PHE328
B	LEU5-PHE22
B	TYR32-ILE48
B	ILE105-LEU122
B	ILE312-PHE328

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site_id	SWS_FT_FI3
Number of Residues	392
Details	TOPO_DOM: Cytoplasmic => ECO:0000250|UniProtKB:P12287

Chain	Residue	Details
A	ARG23-ASN31
A	LYS123-LEU311
B	ARG23-ASN31
B	LYS123-LEU311

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site_id	SWS_FT_FI4
Number of Residues	2
Details	ACT_SITE: Acyl-ester intermediate => ECO:0000269|PubMed:15506754, ECO:0000269|PubMed:21775440

Chain	Residue	Details
A	SER389
B	SER389

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site_id	SWS_FT_FI5
Number of Residues	2
Details	MOD_RES: N6-carboxylysine => ECO:0000269|PubMed:12591921

Chain	Residue	Details
A	LYS392
B	LYS392

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