8ES7
CryoEM structure of PN45545 TCR-CD3 complex
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| D | 0004888 | molecular_function | transmembrane signaling receptor activity |
| D | 0007166 | biological_process | cell surface receptor signaling pathway |
| D | 0016020 | cellular_component | membrane |
| E | 0004888 | molecular_function | transmembrane signaling receptor activity |
| E | 0007166 | biological_process | cell surface receptor signaling pathway |
| E | 0016020 | cellular_component | membrane |
| F | 0004888 | molecular_function | transmembrane signaling receptor activity |
| F | 0007166 | biological_process | cell surface receptor signaling pathway |
| F | 0016020 | cellular_component | membrane |
| G | 0004888 | molecular_function | transmembrane signaling receptor activity |
| G | 0007166 | biological_process | cell surface receptor signaling pathway |
| G | 0016020 | cellular_component | membrane |
| Y | 0004888 | molecular_function | transmembrane signaling receptor activity |
| Y | 0007166 | biological_process | cell surface receptor signaling pathway |
| Y | 0016020 | cellular_component | membrane |
| Z | 0004888 | molecular_function | transmembrane signaling receptor activity |
| Z | 0007166 | biological_process | cell surface receptor signaling pathway |
| Z | 0016020 | cellular_component | membrane |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 93 |
| Details | TOPO_DOM: Extracellular => ECO:0000255 |
| Chain | Residue | Details |
| G | GLN23-SER116 | |
| E | ASP23-ASP126 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 20 |
| Details | TRANSMEM: Helical => ECO:0000255 |
| Chain | Residue | Details |
| G | GLY117-ALA137 | |
| E | VAL127-SER152 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 44 |
| Details | TOPO_DOM: Cytoplasmic => ECO:0000255 |
| Chain | Residue | Details |
| G | GLY138-ASN182 | |
| E | LYS153-ILE207 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphoserine => ECO:0000269|PubMed:2540970, ECO:0000269|PubMed:3112151 |
| Chain | Residue | Details |
| G | SER145 | |
| E | TYR188 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphoserine; by PKC => ECO:0000269|PubMed:2540970, ECO:0000269|PubMed:3112151, ECO:0000269|PubMed:8187769 |
| Chain | Residue | Details |
| G | SER148 | |
| E | TYR199 | |
| Y | TYR64 | |
| Y | TYR72 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:8636209 |
| Chain | Residue | Details |
| G | ASN52 | |
| G | ASN92 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 4 |
| Details | MOD_RES: Phosphotyrosine => ECO:0007744|PubMed:12522270, ECO:0007744|PubMed:15144186, ECO:0007744|PubMed:15592455, ECO:0007744|PubMed:19690332 |
| Chain | Residue | Details |
| Z | TYR111 | |
| Z | TYR142 | |
| Y | TYR111 | |
| Y | TYR142 |
| site_id | SWS_FT_FI8 |
| Number of Residues | 4 |
| Details | MOD_RES: Phosphotyrosine => ECO:0007744|PubMed:19690332 |
| Chain | Residue | Details |
| Z | TYR123 | |
| Z | TYR153 | |
| Y | TYR123 | |
| Y | TYR153 |
