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8ENK

Crystal structure of UAP56 in complex with Tho1, the yeast homolog of human SARNP

Functional Information from GO Data
ChainGOidnamespacecontents
A0000245biological_processspliceosomal complex assembly
A0000346cellular_componenttranscription export complex
A0000398biological_processmRNA splicing, via spliceosome
A0003676molecular_functionnucleic acid binding
A0003689molecular_functionDNA clamp loader activity
A0003723molecular_functionRNA binding
A0003724molecular_functionRNA helicase activity
A0003729molecular_functionmRNA binding
A0004386molecular_functionhelicase activity
A0005515molecular_functionprotein binding
A0005524molecular_functionATP binding
A0005634cellular_componentnucleus
A0005654cellular_componentnucleoplasm
A0005681cellular_componentspliceosomal complex
A0005687cellular_componentU4 snRNP
A0005688cellular_componentU6 snRNP
A0005737cellular_componentcytoplasm
A0006338biological_processchromatin remodeling
A0006397biological_processmRNA processing
A0006405biological_processRNA export from nucleus
A0006406biological_processmRNA export from nucleus
A0008186molecular_functionATP-dependent activity, acting on RNA
A0008380biological_processRNA splicing
A0010501biological_processRNA secondary structure unwinding
A0016607cellular_componentnuclear speck
A0016787molecular_functionhydrolase activity
A0016887molecular_functionATP hydrolysis activity
A0017070molecular_functionU6 snRNA binding
A0030621molecular_functionU4 snRNA binding
A0042802molecular_functionidentical protein binding
A0043008molecular_functionATP-dependent protein binding
A0051028biological_processmRNA transport
A0061775molecular_functioncohesin loader activity
A0140584molecular_functionchromatin extrusion motor activity
A0140588biological_processchromatin looping
A0140665molecular_functionATP-dependent H3-H4 histone complex chaperone activity
A0140849molecular_functionATP-dependent H2AZ histone chaperone activity
B0000245biological_processspliceosomal complex assembly
B0000346cellular_componenttranscription export complex
B0000398biological_processmRNA splicing, via spliceosome
B0003676molecular_functionnucleic acid binding
B0003689molecular_functionDNA clamp loader activity
B0003723molecular_functionRNA binding
B0003724molecular_functionRNA helicase activity
B0003729molecular_functionmRNA binding
B0004386molecular_functionhelicase activity
B0005515molecular_functionprotein binding
B0005524molecular_functionATP binding
B0005634cellular_componentnucleus
B0005654cellular_componentnucleoplasm
B0005681cellular_componentspliceosomal complex
B0005687cellular_componentU4 snRNP
B0005688cellular_componentU6 snRNP
B0005737cellular_componentcytoplasm
B0006338biological_processchromatin remodeling
B0006397biological_processmRNA processing
B0006405biological_processRNA export from nucleus
B0006406biological_processmRNA export from nucleus
B0008186molecular_functionATP-dependent activity, acting on RNA
B0008380biological_processRNA splicing
B0010501biological_processRNA secondary structure unwinding
B0016607cellular_componentnuclear speck
B0016787molecular_functionhydrolase activity
B0016887molecular_functionATP hydrolysis activity
B0017070molecular_functionU6 snRNA binding
B0030621molecular_functionU4 snRNA binding
B0042802molecular_functionidentical protein binding
B0043008molecular_functionATP-dependent protein binding
B0051028biological_processmRNA transport
B0061775molecular_functioncohesin loader activity
B0140584molecular_functionchromatin extrusion motor activity
B0140588biological_processchromatin looping
B0140665molecular_functionATP-dependent H3-H4 histone complex chaperone activity
B0140849molecular_functionATP-dependent H2AZ histone chaperone activity
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues2
DetailsBINDING:
ChainResidueDetails
AALA89
BALA89

site_idSWS_FT_FI2
Number of Residues2
DetailsMOD_RES: Phosphothreonine => ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:23186163
ChainResidueDetails
ATHR172
BTHR172

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PDB entries from 2024-11-06

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