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8EMV

Phospholipase C beta 3 (PLCb3) in solution

Functional Information from GO Data
ChainGOidnamespacecontents
A0003073biological_processregulation of systemic arterial blood pressure
A0004435molecular_functionphosphatidylinositol phospholipase C activity
A0004629molecular_functionphospholipase C activity
A0005509molecular_functioncalcium ion binding
A0005515molecular_functionprotein binding
A0005516molecular_functioncalmodulin binding
A0005634cellular_componentnucleus
A0005737cellular_componentcytoplasm
A0005829cellular_componentcytosol
A0006629biological_processlipid metabolic process
A0007165biological_processsignal transduction
A0007186biological_processG protein-coupled receptor signaling pathway
A0007200biological_processphospholipase C-activating G protein-coupled receptor signaling pathway
A0007208biological_processphospholipase C-activating serotonin receptor signaling pathway
A0008081molecular_functionphosphoric diester hydrolase activity
A0016020cellular_componentmembrane
A0016042biological_processlipid catabolic process
A0016787molecular_functionhydrolase activity
A0032991cellular_componentprotein-containing complex
A0035556biological_processintracellular signal transduction
A0045296molecular_functioncadherin binding
A0046488biological_processphosphatidylinositol metabolic process
A0048015biological_processphosphatidylinositol-mediated signaling
A0051209biological_processrelease of sequestered calcium ion into cytosol
A0060090molecular_functionmolecular adaptor activity
A0099524cellular_componentpostsynaptic cytosol
A0140677molecular_functionmolecular function activator activity
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues2
DetailsACT_SITE: ACT_SITE => ECO:0000255|PROSITE-ProRule:PRU00270
ChainResidueDetails
AHIS332
AHIS379

site_idSWS_FT_FI2
Number of Residues2
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:21406692
ChainResidueDetails
ASER474
ASER1105

site_idSWS_FT_FI3
Number of Residues2
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:24275569
ChainResidueDetails
ASER490
ASER495

site_idSWS_FT_FI4
Number of Residues1
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163, ECO:0007744|PubMed:24275569
ChainResidueDetails
ASER537

site_idSWS_FT_FI5
Number of Residues1
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:23186163
ChainResidueDetails
ASER926

227111

PDB entries from 2024-11-06

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