8EMV

Phospholipase C beta 3 (PLCb3) in solution

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003073	biological_process	regulation of systemic arterial blood pressure
A	0004435	molecular_function	phosphatidylinositol-4,5-bisphosphate phospholipase C activity
A	0004629	molecular_function	phospholipase C activity
A	0005509	molecular_function	calcium ion binding
A	0005515	molecular_function	protein binding
A	0005516	molecular_function	calmodulin binding
A	0005634	cellular_component	nucleus
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0006629	biological_process	lipid metabolic process
A	0007165	biological_process	signal transduction
A	0007186	biological_process	G protein-coupled receptor signaling pathway
A	0007200	biological_process	phospholipase C-activating G protein-coupled receptor signaling pathway
A	0007208	biological_process	phospholipase C-activating serotonin receptor signaling pathway
A	0008081	molecular_function	phosphoric diester hydrolase activity
A	0016020	cellular_component	membrane
A	0016042	biological_process	lipid catabolic process
A	0016787	molecular_function	hydrolase activity
A	0032991	cellular_component	protein-containing complex
A	0035556	biological_process	intracellular signal transduction
A	0045296	molecular_function	cadherin binding
A	0046488	biological_process	phosphatidylinositol metabolic process
A	0048015	biological_process	phosphatidylinositol-mediated signaling
A	0051209	biological_process	release of sequestered calcium ion into cytosol
A	0060090	molecular_function	molecular adaptor activity
A	0099524	cellular_component	postsynaptic cytosol
A	0120548	molecular_function	phosphatidylinositol phospholipase C activity
A	0140677	molecular_function	molecular function activator activity

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	150
Details	Domain: {"description":"PI-PLC X-box","evidences":[{"source":"PROSITE-ProRule","id":"PRU00270","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	116
Details	Domain: {"description":"PI-PLC Y-box","evidences":[{"source":"PROSITE-ProRule","id":"PRU00271","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	128
Details	Domain: {"description":"C2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00041","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	11
Details	Compositional bias: {"description":"Polar residues","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	2
Details	Active site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00270","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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