8EFG
Crystal structure of human TATDN1 bound to dAMP and two zinc ions
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004518 | molecular_function | nuclease activity |
| A | 0004520 | molecular_function | DNA endonuclease activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005634 | cellular_component | nucleus |
| A | 0005654 | cellular_component | nucleoplasm |
| A | 0005739 | cellular_component | mitochondrion |
| A | 0006259 | biological_process | DNA metabolic process |
| A | 0008296 | molecular_function | 3'-5'-DNA exonuclease activity |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0016788 | molecular_function | hydrolase activity, acting on ester bonds |
| A | 0046872 | molecular_function | metal ion binding |
Functional Information from PROSITE/UniProt
| site_id | PS01091 |
| Number of Residues | 17 |
| Details | TATD_3 TatD deoxyribonuclease family signature 3. VLksIPsekLMIETDaP |
| Chain | Residue | Details |
| A | VAL208-PRO224 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 6 |
| Details | Binding site: {"evidences":[{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"JUL-2010","submissionDatabase":"PDB data bank","title":"Structure of putative deoxyribonuclease TATDN1 isoform A.","authoringGroup":["Structural genomics consortium (SGC)"]}},{"source":"PDB","id":"8EFG","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"Reference","evidenceCode":"ECO:0000305","citation":{"citationType":"submission","publicationDate":"JUL-2010","submissionDatabase":"PDB data bank","title":"Structure of putative deoxyribonuclease TATDN1 isoform A.","authoringGroup":["Structural genomics consortium (SGC)"]}},{"source":"PDB","id":"8EFG","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"N6-succinyllysine","evidences":[{"source":"UniProtKB","id":"Q6P8M1","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
