8EC6
Cryo-EM structure of the Glutaminase C core filament (fGAC)
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004359 | molecular_function | glutaminase activity |
| A | 0006541 | biological_process | glutamine metabolic process |
| B | 0004359 | molecular_function | glutaminase activity |
| B | 0006541 | biological_process | glutamine metabolic process |
| C | 0004359 | molecular_function | glutaminase activity |
| C | 0006541 | biological_process | glutamine metabolic process |
| D | 0004359 | molecular_function | glutaminase activity |
| D | 0006541 | biological_process | glutamine metabolic process |
| E | 0004359 | molecular_function | glutaminase activity |
| E | 0006541 | biological_process | glutamine metabolic process |
| F | 0004359 | molecular_function | glutaminase activity |
| F | 0006541 | biological_process | glutamine metabolic process |
| G | 0004359 | molecular_function | glutaminase activity |
| G | 0006541 | biological_process | glutamine metabolic process |
| H | 0004359 | molecular_function | glutaminase activity |
| H | 0006541 | biological_process | glutamine metabolic process |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 56 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:22228304, ECO:0007744|PDB:3SS5 |
| Chain | Residue | Details |
| A | SER291 | |
| B | GLU386 | |
| B | ASN393 | |
| B | TYR419 | |
| B | TYR471 | |
| B | VAL489 | |
| C | SER291 | |
| C | ASN340 | |
| C | GLU386 | |
| C | ASN393 | |
| C | TYR419 | |
| A | ASN340 | |
| C | TYR471 | |
| C | VAL489 | |
| D | SER291 | |
| D | ASN340 | |
| D | GLU386 | |
| D | ASN393 | |
| D | TYR419 | |
| D | TYR471 | |
| D | VAL489 | |
| E | SER291 | |
| A | GLU386 | |
| E | ASN340 | |
| E | GLU386 | |
| E | ASN393 | |
| E | TYR419 | |
| E | TYR471 | |
| E | VAL489 | |
| F | SER291 | |
| F | ASN340 | |
| F | GLU386 | |
| F | ASN393 | |
| A | ASN393 | |
| F | TYR419 | |
| F | TYR471 | |
| F | VAL489 | |
| G | SER291 | |
| G | ASN340 | |
| G | GLU386 | |
| G | ASN393 | |
| G | TYR419 | |
| G | TYR471 | |
| G | VAL489 | |
| A | TYR419 | |
| H | SER291 | |
| H | ASN340 | |
| H | GLU386 | |
| H | ASN393 | |
| H | TYR419 | |
| H | TYR471 | |
| H | VAL489 | |
| A | TYR471 | |
| A | VAL489 | |
| B | SER291 | |
| B | ASN340 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 16 |
| Details | MOD_RES: N6-succinyllysine => ECO:0007744|PubMed:23806337 |
| Chain | Residue | Details |
| A | LYS135 | |
| E | LYS169 | |
| F | LYS135 | |
| F | LYS169 | |
| G | LYS135 | |
| G | LYS169 | |
| H | LYS135 | |
| H | LYS169 | |
| A | LYS169 | |
| B | LYS135 | |
| B | LYS169 | |
| C | LYS135 | |
| C | LYS169 | |
| D | LYS135 | |
| D | LYS169 | |
| E | LYS135 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 8 |
| Details | MOD_RES: N6-acetyllysine => ECO:0000250|UniProtKB:O94925 |
| Chain | Residue | Details |
| A | LYS316 | |
| B | LYS316 | |
| C | LYS316 | |
| D | LYS316 | |
| E | LYS316 | |
| F | LYS316 | |
| G | LYS316 | |
| H | LYS316 |
