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8E1O

Crystal structure of hTEAD2 bound to a methoxypyridine lipid pocket binder

Functional Information from PDB Data
site_idAC1
Number of Residues6
Detailsbinding site for residue TRS A 601
ChainResidue
AASP305
ASER433
AGLU434
AARG435
BHIS440
BTYR442

site_idAC2
Number of Residues19
Detailsbinding site for residue Y2S A 602
ChainResidue
AVAL355
ALYS357
APRO378
AMET379
ACYS380
AGLU381
ALEU383
ALEU387
ALEU390
ALEU403
AILE408
AGLN410
ATYR426
APHE428
BGLN353
BGLU356
APHE233
AALA304
ALEU306

site_idAC3
Number of Residues18
Detailsbinding site for residue Y2S B 501
ChainResidue
AVAL358
BPHE233
BALA304
BLEU306
BVAL329
BLYS357
BPRO378
BMET379
BCYS380
BGLU381
BLEU383
BLEU387
BLEU390
BLEU403
BILE408
BGLN410
BTYR426
BHOH603

247536

PDB entries from 2026-01-14

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