8DYS
Crystal structure of human Eukaryotic translation initiation factor 2A (eIF2A)
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000049 | molecular_function | tRNA binding |
| A | 0003729 | molecular_function | mRNA binding |
| A | 0003743 | molecular_function | translation initiation factor activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005615 | cellular_component | extracellular space |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005850 | cellular_component | eukaryotic translation initiation factor 2 complex |
| A | 0006412 | biological_process | translation |
| A | 0006413 | biological_process | translational initiation |
| A | 0006417 | biological_process | regulation of translation |
| A | 0009967 | biological_process | positive regulation of signal transduction |
| A | 0032933 | biological_process | SREBP signaling pathway |
| A | 0042255 | biological_process | ribosome assembly |
| A | 0043022 | molecular_function | ribosome binding |
| A | 0045296 | molecular_function | cadherin binding |
| A | 0072562 | cellular_component | blood microparticle |
| A | 1990928 | biological_process | response to amino acid starvation |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 50 |
| Details | Repeat: {"description":"WD 3"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 41 |
| Details | Repeat: {"description":"WD 5"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 41 |
| Details | Repeat: {"description":"WD 6"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 42 |
| Details | Repeat: {"description":"WD 7"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
