8DP2

Crystal Structure of UDP-N-acetylmuramoylalanine--D-glutamate ligase (MurD) from Pseudomonas aeruginosa PAO1 in complex with UMA (Uridine-5'-diphosphate-N-acetylmuramoyl-L-Alanine)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0005524	molecular_function	ATP binding
A	0005737	cellular_component	cytoplasm
A	0008360	biological_process	regulation of cell shape
A	0008764	molecular_function	UDP-N-acetylmuramoylalanine-D-glutamate ligase activity
A	0009058	biological_process	biosynthetic process
A	0009252	biological_process	peptidoglycan biosynthetic process
A	0016874	molecular_function	ligase activity
A	0016881	molecular_function	acid-amino acid ligase activity
A	0051301	biological_process	cell division
A	0071555	biological_process	cell wall organization

Functional Information from PROSITE/UniProt

site_id	PS00012
Number of Residues	16
Details	PHOSPHOPANTETHEINE Phosphopantetheine attachment site. GSNAKSTVTTLVGEMA

Chain	Residue	Details
A	GLY116-ALA131

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	7
Details	BINDING: BINDING => ECO:0000269|Ref.5, ECO:0007744|PDB:7U35

Chain	Residue	Details
A	LYS17
A	SER18
A	THR38
A	ARG39
A	GLY78
A	ASN143
A	HIS188

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site_id	SWS_FT_FI2
Number of Residues	1
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00639

Chain	Residue	Details
A	GLY116

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site_id	SWS_FT_FI3
Number of Residues	8
Details	BINDING: BINDING => ECO:0000269|Ref.4, ECO:0007744|PDB:7U35

Chain	Residue	Details
A	ALA119
A	LYS120
A	SER121
A	THR122
A	ASN278
A	ARG309
A	ASP324
A	LYS326

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