8DH5

T7 RNA polymerase elongation complex with unnatural base dPa-ATP mismatch

Functional Information from GO Data

Chain	GOid	namespace	contents
B	0000428	cellular_component	DNA-directed RNA polymerase complex
B	0001018	molecular_function	mitochondrial promoter sequence-specific DNA binding
B	0003677	molecular_function	DNA binding
B	0003899	molecular_function	DNA-directed 5'-3' RNA polymerase activity
B	0006351	biological_process	DNA-templated transcription
B	0016779	molecular_function	nucleotidyltransferase activity
B	0019083	biological_process	viral transcription
B	0034062	molecular_function	5'-3' RNA polymerase activity
B	0039695	biological_process	DNA-templated viral transcription
E	0000428	cellular_component	DNA-directed RNA polymerase complex
E	0001018	molecular_function	mitochondrial promoter sequence-specific DNA binding
E	0003677	molecular_function	DNA binding
E	0003899	molecular_function	DNA-directed 5'-3' RNA polymerase activity
E	0006351	biological_process	DNA-templated transcription
E	0016779	molecular_function	nucleotidyltransferase activity
E	0019083	biological_process	viral transcription
E	0034062	molecular_function	5'-3' RNA polymerase activity
E	0039695	biological_process	DNA-templated viral transcription
I	0000428	cellular_component	DNA-directed RNA polymerase complex
I	0001018	molecular_function	mitochondrial promoter sequence-specific DNA binding
I	0003677	molecular_function	DNA binding
I	0003899	molecular_function	DNA-directed 5'-3' RNA polymerase activity
I	0006351	biological_process	DNA-templated transcription
I	0016779	molecular_function	nucleotidyltransferase activity
I	0019083	biological_process	viral transcription
I	0034062	molecular_function	5'-3' RNA polymerase activity
I	0039695	biological_process	DNA-templated viral transcription
M	0000428	cellular_component	DNA-directed RNA polymerase complex
M	0001018	molecular_function	mitochondrial promoter sequence-specific DNA binding
M	0003677	molecular_function	DNA binding
M	0003899	molecular_function	DNA-directed 5'-3' RNA polymerase activity
M	0006351	biological_process	DNA-templated transcription
M	0016779	molecular_function	nucleotidyltransferase activity
M	0019083	biological_process	viral transcription
M	0034062	molecular_function	5'-3' RNA polymerase activity
M	0039695	biological_process	DNA-templated viral transcription

Functional Information from PROSITE/UniProt

site_id	PS00489
Number of Residues	15
Details	RNA_POL_PHAGE_2 Bacteriophage-type RNA polymerase family active site signature 2. VtRsvtKrsVMTlaY

Chain	Residue	Details
B	VAL625-TYR639

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site_id	PS00900
Number of Residues	12
Details	RNA_POL_PHAGE_1 Bacteriophage-type RNA polymerase family active site signature 1. PLafDGSCSGIQ

Chain	Residue	Details
B	PRO533-GLN544

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	8
Details	ACT_SITE: ACT_SITE => ECO:0000269|PubMed:8133519

Chain	Residue	Details
B	ASP537
B	ASP812
E	ASP537
E	ASP812
I	ASP537
I	ASP812
M	ASP537
M	ASP812

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site_id	SWS_FT_FI2
Number of Residues	4
Details	ACT_SITE: ACT_SITE => ECO:0000269|PubMed:1847871, ECO:0000269|PubMed:8133519

Chain	Residue	Details
B	LYS631
E	LYS631
I	LYS631
M	LYS631

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