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8DH3

T7 RNA polymerase elongation complex with unnatural base dPa

Functional Information from GO Data
ChainGOidnamespacecontents
B0000428cellular_componentDNA-directed RNA polymerase complex
B0003677molecular_functionDNA binding
B0003899molecular_functionDNA-directed RNA polymerase activity
B0006351biological_processDNA-templated transcription
B0016740molecular_functiontransferase activity
B0016779molecular_functionnucleotidyltransferase activity
B0019083biological_processviral transcription
B0034062molecular_function5'-3' RNA polymerase activity
B0039695biological_processDNA-templated viral transcription
E0000428cellular_componentDNA-directed RNA polymerase complex
E0003677molecular_functionDNA binding
E0003899molecular_functionDNA-directed RNA polymerase activity
E0006351biological_processDNA-templated transcription
E0016740molecular_functiontransferase activity
E0016779molecular_functionnucleotidyltransferase activity
E0019083biological_processviral transcription
E0034062molecular_function5'-3' RNA polymerase activity
E0039695biological_processDNA-templated viral transcription
I0000428cellular_componentDNA-directed RNA polymerase complex
I0003677molecular_functionDNA binding
I0003899molecular_functionDNA-directed RNA polymerase activity
I0006351biological_processDNA-templated transcription
I0016740molecular_functiontransferase activity
I0016779molecular_functionnucleotidyltransferase activity
I0019083biological_processviral transcription
I0034062molecular_function5'-3' RNA polymerase activity
I0039695biological_processDNA-templated viral transcription
M0000428cellular_componentDNA-directed RNA polymerase complex
M0003677molecular_functionDNA binding
M0003899molecular_functionDNA-directed RNA polymerase activity
M0006351biological_processDNA-templated transcription
M0016740molecular_functiontransferase activity
M0016779molecular_functionnucleotidyltransferase activity
M0019083biological_processviral transcription
M0034062molecular_function5'-3' RNA polymerase activity
M0039695biological_processDNA-templated viral transcription
Functional Information from PROSITE/UniProt
site_idPS00489
Number of Residues15
DetailsRNA_POL_PHAGE_2 Bacteriophage-type RNA polymerase family active site signature 2. VtRsvtKrsVMTlaY
ChainResidueDetails
BVAL625-TYR639

site_idPS00900
Number of Residues12
DetailsRNA_POL_PHAGE_1 Bacteriophage-type RNA polymerase family active site signature 1. PLafDGSCSGIQ
ChainResidueDetails
BPRO533-GLN544

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues8
DetailsActive site: {"evidences":[{"source":"PubMed","id":"8133519","evidenceCode":"ECO:0000269"}]}
ChainResidueDetails

site_idSWS_FT_FI2
Number of Residues4
DetailsActive site: {"evidences":[{"source":"PubMed","id":"1847871","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"8133519","evidenceCode":"ECO:0000269"}]}
ChainResidueDetails

239149

PDB entries from 2025-07-23

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