8DG4

Group A streptococcus Enolase K252A, K255A, K434A, K435A mutant

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000015	cellular_component	phosphopyruvate hydratase complex
A	0000287	molecular_function	magnesium ion binding
A	0004634	molecular_function	phosphopyruvate hydratase activity
A	0005576	cellular_component	extracellular region
A	0005737	cellular_component	cytoplasm
A	0006096	biological_process	glycolytic process
A	0009274	cellular_component	peptidoglycan-based cell wall
A	0009986	cellular_component	cell surface
A	0016829	molecular_function	lyase activity
A	0046872	molecular_function	metal ion binding
B	0000015	cellular_component	phosphopyruvate hydratase complex
B	0000287	molecular_function	magnesium ion binding
B	0004634	molecular_function	phosphopyruvate hydratase activity
B	0005576	cellular_component	extracellular region
B	0005737	cellular_component	cytoplasm
B	0006096	biological_process	glycolytic process
B	0009274	cellular_component	peptidoglycan-based cell wall
B	0009986	cellular_component	cell surface
B	0016829	molecular_function	lyase activity
B	0046872	molecular_function	metal ion binding
C	0000015	cellular_component	phosphopyruvate hydratase complex
C	0000287	molecular_function	magnesium ion binding
C	0004634	molecular_function	phosphopyruvate hydratase activity
C	0005576	cellular_component	extracellular region
C	0005737	cellular_component	cytoplasm
C	0006096	biological_process	glycolytic process
C	0009274	cellular_component	peptidoglycan-based cell wall
C	0009986	cellular_component	cell surface
C	0016829	molecular_function	lyase activity
C	0046872	molecular_function	metal ion binding
D	0000015	cellular_component	phosphopyruvate hydratase complex
D	0000287	molecular_function	magnesium ion binding
D	0004634	molecular_function	phosphopyruvate hydratase activity
D	0005576	cellular_component	extracellular region
D	0005737	cellular_component	cytoplasm
D	0006096	biological_process	glycolytic process
D	0009274	cellular_component	peptidoglycan-based cell wall
D	0009986	cellular_component	cell surface
D	0016829	molecular_function	lyase activity
D	0046872	molecular_function	metal ion binding
E	0000015	cellular_component	phosphopyruvate hydratase complex
E	0000287	molecular_function	magnesium ion binding
E	0004634	molecular_function	phosphopyruvate hydratase activity
E	0005576	cellular_component	extracellular region
E	0005737	cellular_component	cytoplasm
E	0006096	biological_process	glycolytic process
E	0009274	cellular_component	peptidoglycan-based cell wall
E	0009986	cellular_component	cell surface
E	0016829	molecular_function	lyase activity
E	0046872	molecular_function	metal ion binding
F	0000015	cellular_component	phosphopyruvate hydratase complex
F	0000287	molecular_function	magnesium ion binding
F	0004634	molecular_function	phosphopyruvate hydratase activity
F	0005576	cellular_component	extracellular region
F	0005737	cellular_component	cytoplasm
F	0006096	biological_process	glycolytic process
F	0009274	cellular_component	peptidoglycan-based cell wall
F	0009986	cellular_component	cell surface
F	0016829	molecular_function	lyase activity
F	0046872	molecular_function	metal ion binding
G	0000015	cellular_component	phosphopyruvate hydratase complex
G	0000287	molecular_function	magnesium ion binding
G	0004634	molecular_function	phosphopyruvate hydratase activity
G	0005576	cellular_component	extracellular region
G	0005737	cellular_component	cytoplasm
G	0006096	biological_process	glycolytic process
G	0009274	cellular_component	peptidoglycan-based cell wall
G	0009986	cellular_component	cell surface
G	0016829	molecular_function	lyase activity
G	0046872	molecular_function	metal ion binding
H	0000015	cellular_component	phosphopyruvate hydratase complex
H	0000287	molecular_function	magnesium ion binding
H	0004634	molecular_function	phosphopyruvate hydratase activity
H	0005576	cellular_component	extracellular region
H	0005737	cellular_component	cytoplasm
H	0006096	biological_process	glycolytic process
H	0009274	cellular_component	peptidoglycan-based cell wall
H	0009986	cellular_component	cell surface
H	0016829	molecular_function	lyase activity
H	0046872	molecular_function	metal ion binding

Functional Information from PROSITE/UniProt

site_id	PS00164
Number of Residues	14
Details	ENOLASE Enolase signature. ILIKvNQIGTLTET

Chain	Residue	Details
E	ILE341-THR354

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	8
Details	Active site: {"description":"Proton donor","evidences":[{"source":"HAMAP-Rule","id":"MF_00318","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	8
Details	Active site: {"description":"Proton acceptor","evidences":[{"source":"HAMAP-Rule","id":"MF_00318","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	72
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00318","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	8
Details	Binding site: {"description":"covalent; in inhibited form","evidences":[{"source":"HAMAP-Rule","id":"MF_00318","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---