Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| B | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| B | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 33 |
| Details | binding site for residue G52 A 201 |
| Chain | Residue |
| A | ASP25 |
| A | PRO81 |
| A | VAL82 |
| A | HOH330 |
| A | HOH337 |
| A | HOH339 |
| A | HOH344 |
| A | HOH354 |
| A | HOH391 |
| B | ARG8 |
| B | ASP25 |
| A | GLY27 |
| B | GLY27 |
| B | ALA28 |
| B | ASP29 |
| B | ASP30 |
| B | ILE32 |
| B | GLN48 |
| B | GLY49 |
| B | ILE50 |
| B | PRO81 |
| B | VAL82 |
| A | ALA28 |
| B | HOH218 |
| B | HOH245 |
| B | HOH260 |
| B | HOH282 |
| A | ASP29 |
| A | ASP30 |
| A | ILE32 |
| A | GLN48 |
| A | GLY49 |
| A | ILE50 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | binding site for residue CL A 202 |
| Chain | Residue |
| A | GLY73 |
| A | SER74 |
| A | ASN88 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | binding site for residue CL B 101 |
| Chain | Residue |
| B | GLY73 |
| B | SER74 |
| B | ASN88 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | binding site for residue GOL B 102 |
| Chain | Residue |
| B | GLY16 |
| B | ILE46 |
| B | PRO63 |
| B | HOH223 |
| B | HOH304 |
Functional Information from PROSITE/UniProt
| site_id | PS00141 |
| Number of Residues | 12 |
| Details | ASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. ALLDTGADDTII |
| Chain | Residue | Details |
| A | ALA22-ILE33 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | ASP25 | |
| B | ASP25 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | SITE: Cleavage; by viral protease => ECO:0000250 |
| Chain | Residue | Details |
| A | PHE99 | |
| B | PHE99 | |
