Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

8CZO

Cryo-EM structure of BCL10 CARD - MALT1 DD filament

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0006915	biological_process	apoptotic process
A	0042981	biological_process	regulation of apoptotic process
A	0051092	biological_process	positive regulation of NF-kappaB transcription factor activity
B	0006915	biological_process	apoptotic process
B	0042981	biological_process	regulation of apoptotic process
B	0051092	biological_process	positive regulation of NF-kappaB transcription factor activity
C	0006915	biological_process	apoptotic process
C	0042981	biological_process	regulation of apoptotic process
C	0051092	biological_process	positive regulation of NF-kappaB transcription factor activity
D	0006915	biological_process	apoptotic process
D	0042981	biological_process	regulation of apoptotic process
D	0051092	biological_process	positive regulation of NF-kappaB transcription factor activity
E	0006915	biological_process	apoptotic process
E	0042981	biological_process	regulation of apoptotic process
E	0051092	biological_process	positive regulation of NF-kappaB transcription factor activity
F	0006915	biological_process	apoptotic process
F	0042981	biological_process	regulation of apoptotic process
F	0051092	biological_process	positive regulation of NF-kappaB transcription factor activity
G	0006915	biological_process	apoptotic process
G	0042981	biological_process	regulation of apoptotic process
G	0051092	biological_process	positive regulation of NF-kappaB transcription factor activity
H	0006915	biological_process	apoptotic process
H	0042981	biological_process	regulation of apoptotic process
H	0051092	biological_process	positive regulation of NF-kappaB transcription factor activity
I	0006915	biological_process	apoptotic process
I	0042981	biological_process	regulation of apoptotic process
I	0051092	biological_process	positive regulation of NF-kappaB transcription factor activity
J	0006915	biological_process	apoptotic process
J	0042981	biological_process	regulation of apoptotic process
J	0051092	biological_process	positive regulation of NF-kappaB transcription factor activity
K	0006915	biological_process	apoptotic process
K	0042981	biological_process	regulation of apoptotic process
K	0051092	biological_process	positive regulation of NF-kappaB transcription factor activity
L	0006915	biological_process	apoptotic process
L	0042981	biological_process	regulation of apoptotic process
L	0051092	biological_process	positive regulation of NF-kappaB transcription factor activity
M	0006915	biological_process	apoptotic process
M	0042981	biological_process	regulation of apoptotic process
M	0051092	biological_process	positive regulation of NF-kappaB transcription factor activity
N	0006915	biological_process	apoptotic process
N	0042981	biological_process	regulation of apoptotic process
N	0051092	biological_process	positive regulation of NF-kappaB transcription factor activity
O	0006915	biological_process	apoptotic process
O	0042981	biological_process	regulation of apoptotic process
O	0051092	biological_process	positive regulation of NF-kappaB transcription factor activity
P	0006915	biological_process	apoptotic process
P	0042981	biological_process	regulation of apoptotic process
P	0051092	biological_process	positive regulation of NF-kappaB transcription factor activity
Q	0006915	biological_process	apoptotic process
Q	0042981	biological_process	regulation of apoptotic process
Q	0051092	biological_process	positive regulation of NF-kappaB transcription factor activity
R	0006915	biological_process	apoptotic process
R	0042981	biological_process	regulation of apoptotic process
R	0051092	biological_process	positive regulation of NF-kappaB transcription factor activity
S	0006915	biological_process	apoptotic process
S	0042981	biological_process	regulation of apoptotic process
S	0051092	biological_process	positive regulation of NF-kappaB transcription factor activity
T	0006915	biological_process	apoptotic process
T	0042981	biological_process	regulation of apoptotic process
T	0051092	biological_process	positive regulation of NF-kappaB transcription factor activity
U	0006915	biological_process	apoptotic process
U	0042981	biological_process	regulation of apoptotic process
U	0051092	biological_process	positive regulation of NF-kappaB transcription factor activity
V	0006915	biological_process	apoptotic process
V	0042981	biological_process	regulation of apoptotic process
V	0051092	biological_process	positive regulation of NF-kappaB transcription factor activity

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	22
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269\|PubMed:27777308

Chain	Residue	Details
A	LYS17
J	LYS17
K	LYS17
L	LYS17
M	LYS17
N	LYS17
O	LYS17
P	LYS17
Q	LYS17
R	LYS17
S	LYS17
B	LYS17
T	LYS17
U	LYS17
V	LYS17
C	LYS17
D	LYS17
E	LYS17
F	LYS17
G	LYS17
H	LYS17
I	LYS17

site_id	SWS_FT_FI2
Number of Residues	66
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269\|PubMed:18287044, ECO:0000269\|PubMed:27777308

Chain	Residue	Details
D	LYS31
D	LYS63
E	LYS31
E	LYS63
F	LYS31
F	LYS63
A	LYS31
G	LYS31
G	LYS63
H	LYS31
H	LYS63
I	LYS31
I	LYS63
J	LYS31
A	LYS63
J	LYS63
K	LYS31
K	LYS63
L	LYS31
L	LYS63
M	LYS31
M	LYS63
N	LYS31
N	LYS63
O	LYS31
O	LYS63
P	LYS31
P	LYS63
B	LYS31
Q	LYS31
Q	LYS63
R	LYS31
R	LYS63
S	LYS31
S	LYS63
T	LYS31
B	LYS63
T	LYS63
U	LYS31
U	LYS63
V	LYS31
V	LYS63
C	LYS31
C	LYS63

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)