8CTA

Minimal 2:2 Ternary Complex between BI-224436 bound HIV-1 Integrase Catalytic Core Domain Dimer and Carboxy Terminal Domains

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003676	molecular_function	nucleic acid binding
A	0015074	biological_process	DNA integration
B	0003676	molecular_function	nucleic acid binding
B	0015074	biological_process	DNA integration
C	0003676	molecular_function	nucleic acid binding
D	0003676	molecular_function	nucleic acid binding
E	0003676	molecular_function	nucleic acid binding
E	0015074	biological_process	DNA integration
F	0003676	molecular_function	nucleic acid binding
F	0015074	biological_process	DNA integration
G	0003676	molecular_function	nucleic acid binding
H	0003676	molecular_function	nucleic acid binding
I	0003676	molecular_function	nucleic acid binding
I	0015074	biological_process	DNA integration
J	0003676	molecular_function	nucleic acid binding
J	0015074	biological_process	DNA integration
K	0003676	molecular_function	nucleic acid binding
L	0003676	molecular_function	nucleic acid binding
M	0003676	molecular_function	nucleic acid binding
M	0015074	biological_process	DNA integration
N	0003676	molecular_function	nucleic acid binding
N	0015074	biological_process	DNA integration
O	0003676	molecular_function	nucleic acid binding
P	0003676	molecular_function	nucleic acid binding

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	376
Details	DNA_BIND: Integrase-type => ECO:0000255|PROSITE-ProRule:PRU00506

Chain	Residue	Details
C	PHE223-ASP270
I	ASP116
J	ASP64
J	ASP116
M	ASP64
M	ASP116
N	ASP64
N	ASP116
D	PHE223-ASP270
G	PHE223-ASP270
H	PHE223-ASP270
K	PHE223-ASP270
L	PHE223-ASP270
O	PHE223-ASP270
P	PHE223-ASP270
I	ASP64

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site_id	SWS_FT_FI2
Number of Residues	8
Details	BINDING: BINDING => ECO:0000250|UniProtKB:P04585

Chain	Residue	Details
A	GLU152
B	GLU152
E	GLU152
F	GLU152
I	GLU152
J	GLU152
M	GLU152
N	GLU152

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