8CQZ
Homo sapiens Get3 in complex with the Get1 cytoplasmic domain
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0005515 | molecular_function | protein binding |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005634 | cellular_component | nucleus |
| A | 0005654 | cellular_component | nucleoplasm |
| A | 0005730 | cellular_component | nucleolus |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005783 | cellular_component | endoplasmic reticulum |
| A | 0005789 | cellular_component | endoplasmic reticulum membrane |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0016887 | molecular_function | ATP hydrolysis activity |
| A | 0019885 | biological_process | antigen processing and presentation of endogenous peptide antigen via MHC class I |
| A | 0032977 | molecular_function | membrane insertase activity |
| A | 0043529 | cellular_component | GET complex |
| A | 0045048 | biological_process | protein insertion into ER membrane |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0070062 | cellular_component | extracellular exosome |
| A | 0071816 | biological_process | tail-anchored membrane protein insertion into ER membrane |
| B | 0071816 | biological_process | tail-anchored membrane protein insertion into ER membrane |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | ACT_SITE: ACT_SITE => ECO:0000255|HAMAP-Rule:MF_03112 |
| Chain | Residue | Details |
| A | ASP74 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 8 |
| Details | BINDING: BINDING => ECO:0000250|UniProtKB:Q6IQE5, ECO:0000255|HAMAP-Rule:MF_03112 |
| Chain | Residue | Details |
| A | LYS45 | |
| A | GLY46 | |
| A | GLY49 | |
| A | LYS50 | |
| A | THR51 | |
| A | THR52 | |
| A | GLU251 | |
| A | ASN278 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_03112, ECO:0000269|PubMed:32910895, ECO:0000269|PubMed:37963916, ECO:0007744|PDB:6SO5, ECO:0007744|PDB:8CR1, ECO:0007744|PDB:8CR2 |
| Chain | Residue | Details |
| A | CYS289 | |
| A | CYS292 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000250|UniProtKB:Q6IQE5 |
| Chain | Residue | Details |
| A | PRO319 | |
| A | LEU321 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | MOD_RES: N-acetylalanine => ECO:0007744|PubMed:19413330 |
| Chain | Residue | Details |
| A | ALA2 |
