8CQZ
Homo sapiens Get3 in complex with the Get1 cytoplasmic domain
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0005515 | molecular_function | protein binding |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005654 | cellular_component | nucleoplasm |
| A | 0005730 | cellular_component | nucleolus |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005783 | cellular_component | endoplasmic reticulum |
| A | 0005789 | cellular_component | endoplasmic reticulum membrane |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0016887 | molecular_function | ATP hydrolysis activity |
| A | 0043529 | cellular_component | GET complex |
| A | 0045048 | biological_process | protein insertion into ER membrane |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0070062 | cellular_component | extracellular exosome |
| A | 0071816 | biological_process | tail-anchored membrane protein insertion into ER membrane |
| A | 0140597 | molecular_function | protein carrier chaperone |
| B | 0071816 | biological_process | tail-anchored membrane protein insertion into ER membrane |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Active site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_03112","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 8 |
| Details | Binding site: {"evidences":[{"source":"UniProtKB","id":"Q6IQE5","evidenceCode":"ECO:0000250"},{"source":"HAMAP-Rule","id":"MF_03112","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_03112","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"32910895","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"37963916","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6SO5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8CR1","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8CR2","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"UniProtKB","id":"Q6IQE5","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 58 |
| Details | Region: {"description":"Interaction with GET3/TRC40"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 55 |
| Details | Coiled coil: {"evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
