8CEV

Crystal structure of monkeypox virus methyltransferase VP39 in complex with inhibitor TO1119

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003746	molecular_function	translation elongation factor activity
A	0004483	molecular_function	methyltransferase cap1 activity
A	0006370	biological_process	7-methylguanosine mRNA capping
A	0006397	biological_process	mRNA processing
A	0008168	molecular_function	methyltransferase activity
A	0016740	molecular_function	transferase activity
A	0031440	biological_process	regulation of mRNA 3'-end processing
A	0032259	biological_process	methylation
A	0044423	cellular_component	virion component
B	0003746	molecular_function	translation elongation factor activity
B	0004483	molecular_function	methyltransferase cap1 activity
B	0006370	biological_process	7-methylguanosine mRNA capping
B	0006397	biological_process	mRNA processing
B	0008168	molecular_function	methyltransferase activity
B	0016740	molecular_function	transferase activity
B	0031440	biological_process	regulation of mRNA 3'-end processing
B	0032259	biological_process	methylation
B	0044423	cellular_component	virion component

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	Active site: {"description":"For methyltransferase activity","evidences":[{"source":"PROSITE-ProRule","id":"PRU00944","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	32
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00944","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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