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8C1S

Transmembrane domain of resting state homomeric GluA2 F231A mutant AMPA receptor in complex with TARP gamma 2

Functional Information from GO Data
ChainGOidnamespacecontents
A0000149molecular_functionSNARE binding
A0001540molecular_functionamyloid-beta binding
A0001919biological_processregulation of receptor recycling
A0004970molecular_functionglutamate-gated receptor activity
A0004971molecular_functionAMPA glutamate receptor activity
A0005216molecular_functionmonoatomic ion channel activity
A0005230molecular_functionextracellular ligand-gated monoatomic ion channel activity
A0005234molecular_functionextracellularly glutamate-gated ion channel activity
A0005515molecular_functionprotein binding
A0005783cellular_componentendoplasmic reticulum
A0005886cellular_componentplasma membrane
A0006811biological_processmonoatomic ion transport
A0007268biological_processchemical synaptic transmission
A0008021cellular_componentsynaptic vesicle
A0008092molecular_functioncytoskeletal protein binding
A0008328cellular_componentionotropic glutamate receptor complex
A0009986cellular_componentcell surface
A0010226biological_processresponse to lithium ion
A0014069cellular_componentpostsynaptic density
A0015276molecular_functionligand-gated monoatomic ion channel activity
A0015277molecular_functionkainate selective glutamate receptor activity
A0016020cellular_componentmembrane
A0019722biological_processcalcium-mediated signaling
A0019865molecular_functionimmunoglobulin binding
A0019901molecular_functionprotein kinase binding
A0021987biological_processcerebral cortex development
A0022849molecular_functionglutamate-gated calcium ion channel activity
A0030165molecular_functionPDZ domain binding
A0030424cellular_componentaxon
A0030425cellular_componentdendrite
A0030426cellular_componentgrowth cone
A0030672cellular_componentsynaptic vesicle membrane
A0031623biological_processreceptor internalization
A0032279cellular_componentasymmetric synapse
A0032281cellular_componentAMPA glutamate receptor complex
A0032590cellular_componentdendrite membrane
A0032839cellular_componentdendrite cytoplasm
A0032991cellular_componentprotein-containing complex
A0034220biological_processmonoatomic ion transmembrane transport
A0035235biological_processionotropic glutamate receptor signaling pathway
A0035249biological_processsynaptic transmission, glutamatergic
A0035254molecular_functionglutamate receptor binding
A0035255molecular_functionionotropic glutamate receptor binding
A0036477cellular_componentsomatodendritic compartment
A0038023molecular_functionsignaling receptor activity
A0042734cellular_componentpresynaptic membrane
A0042802molecular_functionidentical protein binding
A0043005cellular_componentneuron projection
A0043025cellular_componentneuronal cell body
A0043195cellular_componentterminal bouton
A0043197cellular_componentdendritic spine
A0043198cellular_componentdendritic shaft
A0043204cellular_componentperikaryon
A0044326cellular_componentdendritic spine neck
A0044327cellular_componentdendritic spine head
A0044877molecular_functionprotein-containing complex binding
A0045184biological_processestablishment of protein localization
A0045202cellular_componentsynapse
A0045211cellular_componentpostsynaptic membrane
A0048787cellular_componentpresynaptic active zone membrane
A0050804biological_processmodulation of chemical synaptic transmission
A0050806biological_processpositive regulation of synaptic transmission
A0051262biological_processprotein tetramerization
A0051966biological_processregulation of synaptic transmission, glutamatergic
A0060078biological_processregulation of postsynaptic membrane potential
A0060079biological_processexcitatory postsynaptic potential
A0060992biological_processresponse to fungicide
A0097060cellular_componentsynaptic membrane
A0097110molecular_functionscaffold protein binding
A0098655biological_processmonoatomic cation transmembrane transport
A0098685cellular_componentSchaffer collateral - CA1 synapse
A0098793cellular_componentpresynapse
A0098839cellular_componentpostsynaptic density membrane
A0098978cellular_componentglutamatergic synapse
A0099094molecular_functionligand-gated monoatomic cation channel activity
A0099505biological_processregulation of presynaptic membrane potential
A0099507molecular_functionligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential
A0099544cellular_componentperisynaptic space
A0106033cellular_componentspine synapse
A1904315molecular_functiontransmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential
A1905430biological_processcellular response to glycine
A1990416biological_processcellular response to brain-derived neurotrophic factor stimulus
B0000149molecular_functionSNARE binding
B0001540molecular_functionamyloid-beta binding
B0001919biological_processregulation of receptor recycling
B0004970molecular_functionglutamate-gated receptor activity
B0004971molecular_functionAMPA glutamate receptor activity
B0005216molecular_functionmonoatomic ion channel activity
B0005230molecular_functionextracellular ligand-gated monoatomic ion channel activity
B0005234molecular_functionextracellularly glutamate-gated ion channel activity
B0005515molecular_functionprotein binding
B0005783cellular_componentendoplasmic reticulum
B0005886cellular_componentplasma membrane
B0006811biological_processmonoatomic ion transport
B0007268biological_processchemical synaptic transmission
B0008021cellular_componentsynaptic vesicle
B0008092molecular_functioncytoskeletal protein binding
B0008328cellular_componentionotropic glutamate receptor complex
B0009986cellular_componentcell surface
B0010226biological_processresponse to lithium ion
B0014069cellular_componentpostsynaptic density
B0015276molecular_functionligand-gated monoatomic ion channel activity
B0015277molecular_functionkainate selective glutamate receptor activity
B0016020cellular_componentmembrane
B0019722biological_processcalcium-mediated signaling
B0019865molecular_functionimmunoglobulin binding
B0019901molecular_functionprotein kinase binding
B0021987biological_processcerebral cortex development
B0022849molecular_functionglutamate-gated calcium ion channel activity
B0030165molecular_functionPDZ domain binding
B0030424cellular_componentaxon
B0030425cellular_componentdendrite
B0030426cellular_componentgrowth cone
B0030672cellular_componentsynaptic vesicle membrane
B0031623biological_processreceptor internalization
B0032279cellular_componentasymmetric synapse
B0032281cellular_componentAMPA glutamate receptor complex
B0032590cellular_componentdendrite membrane
B0032839cellular_componentdendrite cytoplasm
B0032991cellular_componentprotein-containing complex
B0034220biological_processmonoatomic ion transmembrane transport
B0035235biological_processionotropic glutamate receptor signaling pathway
B0035249biological_processsynaptic transmission, glutamatergic
B0035254molecular_functionglutamate receptor binding
B0035255molecular_functionionotropic glutamate receptor binding
B0036477cellular_componentsomatodendritic compartment
B0038023molecular_functionsignaling receptor activity
B0042734cellular_componentpresynaptic membrane
B0042802molecular_functionidentical protein binding
B0043005cellular_componentneuron projection
B0043025cellular_componentneuronal cell body
B0043195cellular_componentterminal bouton
B0043197cellular_componentdendritic spine
B0043198cellular_componentdendritic shaft
B0043204cellular_componentperikaryon
B0044326cellular_componentdendritic spine neck
B0044327cellular_componentdendritic spine head
B0044877molecular_functionprotein-containing complex binding
B0045184biological_processestablishment of protein localization
B0045202cellular_componentsynapse
B0045211cellular_componentpostsynaptic membrane
B0048787cellular_componentpresynaptic active zone membrane
B0050804biological_processmodulation of chemical synaptic transmission
B0050806biological_processpositive regulation of synaptic transmission
B0051262biological_processprotein tetramerization
B0051966biological_processregulation of synaptic transmission, glutamatergic
B0060078biological_processregulation of postsynaptic membrane potential
B0060079biological_processexcitatory postsynaptic potential
B0060992biological_processresponse to fungicide
B0097060cellular_componentsynaptic membrane
B0097110molecular_functionscaffold protein binding
B0098655biological_processmonoatomic cation transmembrane transport
B0098685cellular_componentSchaffer collateral - CA1 synapse
B0098793cellular_componentpresynapse
B0098839cellular_componentpostsynaptic density membrane
B0098978cellular_componentglutamatergic synapse
B0099094molecular_functionligand-gated monoatomic cation channel activity
B0099505biological_processregulation of presynaptic membrane potential
B0099507molecular_functionligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential
B0099544cellular_componentperisynaptic space
B0106033cellular_componentspine synapse
B1904315molecular_functiontransmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential
B1905430biological_processcellular response to glycine
B1990416biological_processcellular response to brain-derived neurotrophic factor stimulus
C0000149molecular_functionSNARE binding
C0001540molecular_functionamyloid-beta binding
C0001919biological_processregulation of receptor recycling
C0004970molecular_functionglutamate-gated receptor activity
C0004971molecular_functionAMPA glutamate receptor activity
C0005216molecular_functionmonoatomic ion channel activity
C0005230molecular_functionextracellular ligand-gated monoatomic ion channel activity
C0005234molecular_functionextracellularly glutamate-gated ion channel activity
C0005515molecular_functionprotein binding
C0005783cellular_componentendoplasmic reticulum
C0005886cellular_componentplasma membrane
C0006811biological_processmonoatomic ion transport
C0007268biological_processchemical synaptic transmission
C0008021cellular_componentsynaptic vesicle
C0008092molecular_functioncytoskeletal protein binding
C0008328cellular_componentionotropic glutamate receptor complex
C0009986cellular_componentcell surface
C0010226biological_processresponse to lithium ion
C0014069cellular_componentpostsynaptic density
C0015276molecular_functionligand-gated monoatomic ion channel activity
C0015277molecular_functionkainate selective glutamate receptor activity
C0016020cellular_componentmembrane
C0019722biological_processcalcium-mediated signaling
C0019865molecular_functionimmunoglobulin binding
C0019901molecular_functionprotein kinase binding
C0021987biological_processcerebral cortex development
C0022849molecular_functionglutamate-gated calcium ion channel activity
C0030165molecular_functionPDZ domain binding
C0030424cellular_componentaxon
C0030425cellular_componentdendrite
C0030426cellular_componentgrowth cone
C0030672cellular_componentsynaptic vesicle membrane
C0031623biological_processreceptor internalization
C0032279cellular_componentasymmetric synapse
C0032281cellular_componentAMPA glutamate receptor complex
C0032590cellular_componentdendrite membrane
C0032839cellular_componentdendrite cytoplasm
C0032991cellular_componentprotein-containing complex
C0034220biological_processmonoatomic ion transmembrane transport
C0035235biological_processionotropic glutamate receptor signaling pathway
C0035249biological_processsynaptic transmission, glutamatergic
C0035254molecular_functionglutamate receptor binding
C0035255molecular_functionionotropic glutamate receptor binding
C0036477cellular_componentsomatodendritic compartment
C0038023molecular_functionsignaling receptor activity
C0042734cellular_componentpresynaptic membrane
C0042802molecular_functionidentical protein binding
C0043005cellular_componentneuron projection
C0043025cellular_componentneuronal cell body
C0043195cellular_componentterminal bouton
C0043197cellular_componentdendritic spine
C0043198cellular_componentdendritic shaft
C0043204cellular_componentperikaryon
C0044326cellular_componentdendritic spine neck
C0044327cellular_componentdendritic spine head
C0044877molecular_functionprotein-containing complex binding
C0045184biological_processestablishment of protein localization
C0045202cellular_componentsynapse
C0045211cellular_componentpostsynaptic membrane
C0048787cellular_componentpresynaptic active zone membrane
C0050804biological_processmodulation of chemical synaptic transmission
C0050806biological_processpositive regulation of synaptic transmission
C0051262biological_processprotein tetramerization
C0051966biological_processregulation of synaptic transmission, glutamatergic
C0060078biological_processregulation of postsynaptic membrane potential
C0060079biological_processexcitatory postsynaptic potential
C0060992biological_processresponse to fungicide
C0097060cellular_componentsynaptic membrane
C0097110molecular_functionscaffold protein binding
C0098655biological_processmonoatomic cation transmembrane transport
C0098685cellular_componentSchaffer collateral - CA1 synapse
C0098793cellular_componentpresynapse
C0098839cellular_componentpostsynaptic density membrane
C0098978cellular_componentglutamatergic synapse
C0099094molecular_functionligand-gated monoatomic cation channel activity
C0099505biological_processregulation of presynaptic membrane potential
C0099507molecular_functionligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential
C0099544cellular_componentperisynaptic space
C0106033cellular_componentspine synapse
C1904315molecular_functiontransmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential
C1905430biological_processcellular response to glycine
C1990416biological_processcellular response to brain-derived neurotrophic factor stimulus
D0000149molecular_functionSNARE binding
D0001540molecular_functionamyloid-beta binding
D0001919biological_processregulation of receptor recycling
D0004970molecular_functionglutamate-gated receptor activity
D0004971molecular_functionAMPA glutamate receptor activity
D0005216molecular_functionmonoatomic ion channel activity
D0005230molecular_functionextracellular ligand-gated monoatomic ion channel activity
D0005234molecular_functionextracellularly glutamate-gated ion channel activity
D0005515molecular_functionprotein binding
D0005783cellular_componentendoplasmic reticulum
D0005886cellular_componentplasma membrane
D0006811biological_processmonoatomic ion transport
D0007268biological_processchemical synaptic transmission
D0008021cellular_componentsynaptic vesicle
D0008092molecular_functioncytoskeletal protein binding
D0008328cellular_componentionotropic glutamate receptor complex
D0009986cellular_componentcell surface
D0010226biological_processresponse to lithium ion
D0014069cellular_componentpostsynaptic density
D0015276molecular_functionligand-gated monoatomic ion channel activity
D0015277molecular_functionkainate selective glutamate receptor activity
D0016020cellular_componentmembrane
D0019722biological_processcalcium-mediated signaling
D0019865molecular_functionimmunoglobulin binding
D0019901molecular_functionprotein kinase binding
D0021987biological_processcerebral cortex development
D0022849molecular_functionglutamate-gated calcium ion channel activity
D0030165molecular_functionPDZ domain binding
D0030424cellular_componentaxon
D0030425cellular_componentdendrite
D0030426cellular_componentgrowth cone
D0030672cellular_componentsynaptic vesicle membrane
D0031623biological_processreceptor internalization
D0032279cellular_componentasymmetric synapse
D0032281cellular_componentAMPA glutamate receptor complex
D0032590cellular_componentdendrite membrane
D0032839cellular_componentdendrite cytoplasm
D0032991cellular_componentprotein-containing complex
D0034220biological_processmonoatomic ion transmembrane transport
D0035235biological_processionotropic glutamate receptor signaling pathway
D0035249biological_processsynaptic transmission, glutamatergic
D0035254molecular_functionglutamate receptor binding
D0035255molecular_functionionotropic glutamate receptor binding
D0036477cellular_componentsomatodendritic compartment
D0038023molecular_functionsignaling receptor activity
D0042734cellular_componentpresynaptic membrane
D0042802molecular_functionidentical protein binding
D0043005cellular_componentneuron projection
D0043025cellular_componentneuronal cell body
D0043195cellular_componentterminal bouton
D0043197cellular_componentdendritic spine
D0043198cellular_componentdendritic shaft
D0043204cellular_componentperikaryon
D0044326cellular_componentdendritic spine neck
D0044327cellular_componentdendritic spine head
D0044877molecular_functionprotein-containing complex binding
D0045184biological_processestablishment of protein localization
D0045202cellular_componentsynapse
D0045211cellular_componentpostsynaptic membrane
D0048787cellular_componentpresynaptic active zone membrane
D0050804biological_processmodulation of chemical synaptic transmission
D0050806biological_processpositive regulation of synaptic transmission
D0051262biological_processprotein tetramerization
D0051966biological_processregulation of synaptic transmission, glutamatergic
D0060078biological_processregulation of postsynaptic membrane potential
D0060079biological_processexcitatory postsynaptic potential
D0060992biological_processresponse to fungicide
D0097060cellular_componentsynaptic membrane
D0097110molecular_functionscaffold protein binding
D0098655biological_processmonoatomic cation transmembrane transport
D0098685cellular_componentSchaffer collateral - CA1 synapse
D0098793cellular_componentpresynapse
D0098839cellular_componentpostsynaptic density membrane
D0098978cellular_componentglutamatergic synapse
D0099094molecular_functionligand-gated monoatomic cation channel activity
D0099505biological_processregulation of presynaptic membrane potential
D0099507molecular_functionligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential
D0099544cellular_componentperisynaptic space
D0106033cellular_componentspine synapse
D1904315molecular_functiontransmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential
D1905430biological_processcellular response to glycine
D1990416biological_processcellular response to brain-derived neurotrophic factor stimulus
E0005245molecular_functionvoltage-gated calcium channel activity
E0005246molecular_functioncalcium channel regulator activity
E0005262molecular_functioncalcium channel activity
E0005515molecular_functionprotein binding
E0005891cellular_componentvoltage-gated calcium channel complex
E0006612biological_processprotein targeting to membrane
E0006816biological_processcalcium ion transport
E0007528biological_processneuromuscular junction development
E0009986cellular_componentcell surface
E0014069cellular_componentpostsynaptic density
E0016020cellular_componentmembrane
E0016247molecular_functionchannel regulator activity
E0019226biological_processtransmission of nerve impulse
E0032281cellular_componentAMPA glutamate receptor complex
E0034702cellular_componentmonoatomic ion channel complex
E0035255molecular_functionionotropic glutamate receptor binding
E0036477cellular_componentsomatodendritic compartment
E0042391biological_processregulation of membrane potential
E0043005cellular_componentneuron projection
E0044300cellular_componentcerebellar mossy fiber
E0045202cellular_componentsynapse
E0050877biological_processnervous system process
E0051592biological_processresponse to calcium ion
E0051899biological_processmembrane depolarization
E0051968biological_processpositive regulation of synaptic transmission, glutamatergic
E0060081biological_processmembrane hyperpolarization
E0060082biological_processeye blink reflex
E0070588biological_processcalcium ion transmembrane transport
E0098685cellular_componentSchaffer collateral - CA1 synapse
E0098686cellular_componenthippocampal mossy fiber to CA3 synapse
E0098839cellular_componentpostsynaptic density membrane
E0098943biological_processneurotransmitter receptor transport, postsynaptic endosome to lysosome
E0098970biological_processpostsynaptic neurotransmitter receptor diffusion trapping
E0098978cellular_componentglutamatergic synapse
E0099072biological_processregulation of postsynaptic membrane neurotransmitter receptor levels
E0099590biological_processneurotransmitter receptor internalization
E0099645biological_processneurotransmitter receptor localization to postsynaptic specialization membrane
E1904510biological_processpositive regulation of protein localization to basolateral plasma membrane
E2000311biological_processregulation of AMPA receptor activity
F0005245molecular_functionvoltage-gated calcium channel activity
F0005246molecular_functioncalcium channel regulator activity
F0005262molecular_functioncalcium channel activity
F0005515molecular_functionprotein binding
F0005891cellular_componentvoltage-gated calcium channel complex
F0006612biological_processprotein targeting to membrane
F0006816biological_processcalcium ion transport
F0007528biological_processneuromuscular junction development
F0009986cellular_componentcell surface
F0014069cellular_componentpostsynaptic density
F0016020cellular_componentmembrane
F0016247molecular_functionchannel regulator activity
F0019226biological_processtransmission of nerve impulse
F0032281cellular_componentAMPA glutamate receptor complex
F0034702cellular_componentmonoatomic ion channel complex
F0035255molecular_functionionotropic glutamate receptor binding
F0036477cellular_componentsomatodendritic compartment
F0042391biological_processregulation of membrane potential
F0043005cellular_componentneuron projection
F0044300cellular_componentcerebellar mossy fiber
F0045202cellular_componentsynapse
F0050877biological_processnervous system process
F0051592biological_processresponse to calcium ion
F0051899biological_processmembrane depolarization
F0051968biological_processpositive regulation of synaptic transmission, glutamatergic
F0060081biological_processmembrane hyperpolarization
F0060082biological_processeye blink reflex
F0070588biological_processcalcium ion transmembrane transport
F0098685cellular_componentSchaffer collateral - CA1 synapse
F0098686cellular_componenthippocampal mossy fiber to CA3 synapse
F0098839cellular_componentpostsynaptic density membrane
F0098943biological_processneurotransmitter receptor transport, postsynaptic endosome to lysosome
F0098970biological_processpostsynaptic neurotransmitter receptor diffusion trapping
F0098978cellular_componentglutamatergic synapse
F0099072biological_processregulation of postsynaptic membrane neurotransmitter receptor levels
F0099590biological_processneurotransmitter receptor internalization
F0099645biological_processneurotransmitter receptor localization to postsynaptic specialization membrane
F1904510biological_processpositive regulation of protein localization to basolateral plasma membrane
F2000311biological_processregulation of AMPA receptor activity
G0005245molecular_functionvoltage-gated calcium channel activity
G0005246molecular_functioncalcium channel regulator activity
G0005262molecular_functioncalcium channel activity
G0005515molecular_functionprotein binding
G0005891cellular_componentvoltage-gated calcium channel complex
G0006612biological_processprotein targeting to membrane
G0006816biological_processcalcium ion transport
G0007528biological_processneuromuscular junction development
G0009986cellular_componentcell surface
G0014069cellular_componentpostsynaptic density
G0016020cellular_componentmembrane
G0016247molecular_functionchannel regulator activity
G0019226biological_processtransmission of nerve impulse
G0032281cellular_componentAMPA glutamate receptor complex
G0034702cellular_componentmonoatomic ion channel complex
G0035255molecular_functionionotropic glutamate receptor binding
G0036477cellular_componentsomatodendritic compartment
G0042391biological_processregulation of membrane potential
G0043005cellular_componentneuron projection
G0044300cellular_componentcerebellar mossy fiber
G0045202cellular_componentsynapse
G0050877biological_processnervous system process
G0051592biological_processresponse to calcium ion
G0051899biological_processmembrane depolarization
G0051968biological_processpositive regulation of synaptic transmission, glutamatergic
G0060081biological_processmembrane hyperpolarization
G0060082biological_processeye blink reflex
G0070588biological_processcalcium ion transmembrane transport
G0098685cellular_componentSchaffer collateral - CA1 synapse
G0098686cellular_componenthippocampal mossy fiber to CA3 synapse
G0098839cellular_componentpostsynaptic density membrane
G0098943biological_processneurotransmitter receptor transport, postsynaptic endosome to lysosome
G0098970biological_processpostsynaptic neurotransmitter receptor diffusion trapping
G0098978cellular_componentglutamatergic synapse
G0099072biological_processregulation of postsynaptic membrane neurotransmitter receptor levels
G0099590biological_processneurotransmitter receptor internalization
G0099645biological_processneurotransmitter receptor localization to postsynaptic specialization membrane
G1904510biological_processpositive regulation of protein localization to basolateral plasma membrane
G2000311biological_processregulation of AMPA receptor activity
H0005245molecular_functionvoltage-gated calcium channel activity
H0005246molecular_functioncalcium channel regulator activity
H0005262molecular_functioncalcium channel activity
H0005515molecular_functionprotein binding
H0005891cellular_componentvoltage-gated calcium channel complex
H0006612biological_processprotein targeting to membrane
H0006816biological_processcalcium ion transport
H0007528biological_processneuromuscular junction development
H0009986cellular_componentcell surface
H0014069cellular_componentpostsynaptic density
H0016020cellular_componentmembrane
H0016247molecular_functionchannel regulator activity
H0019226biological_processtransmission of nerve impulse
H0032281cellular_componentAMPA glutamate receptor complex
H0034702cellular_componentmonoatomic ion channel complex
H0035255molecular_functionionotropic glutamate receptor binding
H0036477cellular_componentsomatodendritic compartment
H0042391biological_processregulation of membrane potential
H0043005cellular_componentneuron projection
H0044300cellular_componentcerebellar mossy fiber
H0045202cellular_componentsynapse
H0050877biological_processnervous system process
H0051592biological_processresponse to calcium ion
H0051899biological_processmembrane depolarization
H0051968biological_processpositive regulation of synaptic transmission, glutamatergic
H0060081biological_processmembrane hyperpolarization
H0060082biological_processeye blink reflex
H0070588biological_processcalcium ion transmembrane transport
H0098685cellular_componentSchaffer collateral - CA1 synapse
H0098686cellular_componenthippocampal mossy fiber to CA3 synapse
H0098839cellular_componentpostsynaptic density membrane
H0098943biological_processneurotransmitter receptor transport, postsynaptic endosome to lysosome
H0098970biological_processpostsynaptic neurotransmitter receptor diffusion trapping
H0098978cellular_componentglutamatergic synapse
H0099072biological_processregulation of postsynaptic membrane neurotransmitter receptor levels
H0099590biological_processneurotransmitter receptor internalization
H0099645biological_processneurotransmitter receptor localization to postsynaptic specialization membrane
H1904510biological_processpositive regulation of protein localization to basolateral plasma membrane
H2000311biological_processregulation of AMPA receptor activity
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues320
DetailsTRANSMEM: Helical => ECO:0000255
ChainResidueDetails
EMET10-THR30
GSER104-ALA124
GILE134-ILE154
GPHE182-ILE202
HMET10-THR30
HSER104-ALA124
HILE134-ILE154
HPHE182-ILE202
ESER104-ALA124
EILE134-ILE154
EPHE182-ILE202
FMET10-THR30
FSER104-ALA124
FILE134-ILE154
FPHE182-ILE202
GMET10-THR30

site_idSWS_FT_FI2
Number of Residues4
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:22673903
ChainResidueDetails
ESER253
FSER253
GSER253
HSER253
CTYR523-VAL543
CLEU596-TYR616
DTYR523-VAL543
DLEU596-TYR616

site_idSWS_FT_FI3
Number of Residues4
DetailsMOD_RES: Phosphotyrosine => ECO:0000250|UniProtKB:O88602
ChainResidueDetails
ETYR271
DSER544-GLU570
DASP590-SER595
DGLU813-ILE862
FTYR271
GTYR271
HTYR271
BASP590-SER595
BGLU813-ILE862
CSER544-GLU570
CASP590-SER595
CGLU813-ILE862

site_idSWS_FT_FI4
Number of Residues4
DetailsMOD_RES: Phosphothreonine; by PKA => ECO:0000250|UniProtKB:O88602
ChainResidueDetails
ETHR321
FTHR321
GTHR321
HTHR321

site_idSWS_FT_FI5
Number of Residues4
DetailsCARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255
ChainResidueDetails
EASN48
FASN48
GASN48
HASN48

site_idSWS_FT_FI6
Number of Residues80
DetailsTRANSMEM: Helical; Name=M4
ChainResidueDetails
AVAL792-ILE812
BVAL792-ILE812
CVAL792-ILE812
DVAL792-ILE812

site_idSWS_FT_FI7
Number of Residues24
DetailsBINDING: BINDING => ECO:0000269|PubMed:11086992, ECO:0000269|PubMed:16483599, ECO:0007744|PDB:1FTJ, ECO:0007744|PDB:2CMO
ChainResidueDetails
APRO478
BSER654
BTHR655
BGLU705
CPRO478
CTHR480
CARG485
CSER654
CTHR655
CGLU705
DPRO478
ATHR480
DTHR480
DARG485
DSER654
DTHR655
DGLU705
AARG485
ASER654
ATHR655
AGLU705
BPRO478
BTHR480
BARG485

site_idSWS_FT_FI8
Number of Residues12
DetailsSITE: Interaction with the cone snail toxin Con-ikot-ikot => ECO:0000269|PubMed:25103405
ChainResidueDetails
AARG453
DARG453
DARG660
DLYS752
AARG660
ALYS752
BARG453
BARG660
BLYS752
CARG453
CARG660
CLYS752

site_idSWS_FT_FI9
Number of Residues4
DetailsSITE: Crucial to convey clamshell closure to channel opening => ECO:0000269|PubMed:25103405
ChainResidueDetails
AILE633
BILE633
CILE633
DILE633

site_idSWS_FT_FI10
Number of Residues4
DetailsMOD_RES: Phosphoserine; by PKC => ECO:0000269|PubMed:8848293
ChainResidueDetails
ASER662
BSER662
CSER662
DSER662

site_idSWS_FT_FI11
Number of Residues4
DetailsMOD_RES: Phosphoserine; by PKG => ECO:0000269|PubMed:8848293
ChainResidueDetails
ASER696
BSER696
CSER696
DSER696

site_idSWS_FT_FI12
Number of Residues12
DetailsMOD_RES: Phosphoserine => ECO:0000250|UniProtKB:P23819
ChainResidueDetails
ASER839
DSER839
DSER842
DSER859
ASER842
ASER859
BSER839
BSER842
BSER859
CSER839
CSER842
CSER859

site_idSWS_FT_FI13
Number of Residues4
DetailsMOD_RES: Phosphotyrosine => ECO:0000269|PubMed:15240807, ECO:0000269|PubMed:20547133
ChainResidueDetails
ATYR855
BTYR855
CTYR855
DTYR855

site_idSWS_FT_FI14
Number of Residues8
DetailsLIPID: S-palmitoyl cysteine => ECO:0000250
ChainResidueDetails
ACYS589
ACYS815
BCYS589
BCYS815
CCYS589
CCYS815
DCYS589
DCYS815

site_idSWS_FT_FI15
Number of Residues4
DetailsCARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:21317873
ChainResidueDetails
AASN235
BASN235
CASN235
DASN235

site_idSWS_FT_FI16
Number of Residues4
DetailsCARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:19946266, ECO:0000269|PubMed:21317873, ECO:0000269|PubMed:25103405
ChainResidueDetails
AASN349
BASN349
CASN349
DASN349

site_idSWS_FT_FI17
Number of Residues8
DetailsCARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255
ChainResidueDetails
AASN385
AASN392
BASN385
BASN392
CASN385
CASN392
DASN385
DASN392

226707

PDB entries from 2024-10-30

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