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8BWI

Crystal structure of human Twisted gastrulation protein homolog 1 (TWSG1), crystal form 2

Functional Information from GO Data
ChainGOidnamespacecontents
A0001818biological_processnegative regulation of cytokine production
A0005515molecular_functionprotein binding
A0005576cellular_componentextracellular region
A0005615cellular_componentextracellular space
A0005813cellular_componentcentrosome
A0005829cellular_componentcytosol
A0008201molecular_functionheparin binding
A0030510biological_processregulation of BMP signaling pathway
A0030511biological_processpositive regulation of transforming growth factor beta receptor signaling pathway
A0050431molecular_functiontransforming growth factor beta binding
A0060391biological_processpositive regulation of SMAD protein signal transduction
A2000515biological_processnegative regulation of CD4-positive, alpha-beta T cell activation
A2000562biological_processnegative regulation of CD4-positive, alpha-beta T cell proliferation
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues2
DetailsGlycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]}
ChainResidueDetails

246905

PDB entries from 2025-12-31

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