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8BWI

Crystal structure of human Twisted gastrulation protein homolog 1 (TWSG1), crystal form 2

Functional Information from GO Data
ChainGOidnamespacecontents
A0001503biological_processossification
A0001707biological_processmesoderm formation
A0001818biological_processnegative regulation of cytokine production
A0002062biological_processchondrocyte differentiation
A0005515molecular_functionprotein binding
A0005576cellular_componentextracellular region
A0005615cellular_componentextracellular space
A0007435biological_processsalivary gland morphogenesis
A0008201molecular_functionheparin binding
A0009888biological_processtissue development
A0030097biological_processhemopoiesis
A0030509biological_processBMP signaling pathway
A0030510biological_processregulation of BMP signaling pathway
A0030511biological_processpositive regulation of transforming growth factor beta receptor signaling pathway
A0030513biological_processpositive regulation of BMP signaling pathway
A0030514biological_processnegative regulation of BMP signaling pathway
A0030900biological_processforebrain development
A0043010biological_processcamera-type eye development
A0045668biological_processnegative regulation of osteoblast differentiation
A0050431molecular_functiontransforming growth factor beta binding
A0060391biological_processpositive regulation of SMAD protein signal transduction
A2000515biological_processnegative regulation of CD4-positive, alpha-beta T cell activation
A2000562biological_processnegative regulation of CD4-positive, alpha-beta T cell proliferation
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues2
DetailsCARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255
ChainResidueDetails
AASN52
AASN81

237423

PDB entries from 2025-06-11

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