8BEO

Crystal structure of E. coli glyoxylate carboligase mutant I393A with MAP

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000287	molecular_function	magnesium ion binding
A	0003824	molecular_function	catalytic activity
A	0005948	cellular_component	acetolactate synthase complex
A	0009028	molecular_function	tartronate-semialdehyde synthase activity
A	0009097	biological_process	isoleucine biosynthetic process
A	0009099	biological_process	L-valine biosynthetic process
A	0009436	biological_process	glyoxylate catabolic process
A	0016829	molecular_function	lyase activity
A	0019752	biological_process	carboxylic acid metabolic process
A	0030976	molecular_function	thiamine pyrophosphate binding
A	0042802	molecular_function	identical protein binding
A	0046296	biological_process	glycolate catabolic process
A	0050660	molecular_function	flavin adenine dinucleotide binding
A	0071949	molecular_function	FAD binding
B	0000287	molecular_function	magnesium ion binding
B	0003824	molecular_function	catalytic activity
B	0005948	cellular_component	acetolactate synthase complex
B	0009028	molecular_function	tartronate-semialdehyde synthase activity
B	0009097	biological_process	isoleucine biosynthetic process
B	0009099	biological_process	L-valine biosynthetic process
B	0009436	biological_process	glyoxylate catabolic process
B	0016829	molecular_function	lyase activity
B	0019752	biological_process	carboxylic acid metabolic process
B	0030976	molecular_function	thiamine pyrophosphate binding
B	0042802	molecular_function	identical protein binding
B	0046296	biological_process	glycolate catabolic process
B	0050660	molecular_function	flavin adenine dinucleotide binding
B	0071949	molecular_function	FAD binding
C	0000287	molecular_function	magnesium ion binding
C	0003824	molecular_function	catalytic activity
C	0005948	cellular_component	acetolactate synthase complex
C	0009028	molecular_function	tartronate-semialdehyde synthase activity
C	0009097	biological_process	isoleucine biosynthetic process
C	0009099	biological_process	L-valine biosynthetic process
C	0009436	biological_process	glyoxylate catabolic process
C	0016829	molecular_function	lyase activity
C	0019752	biological_process	carboxylic acid metabolic process
C	0030976	molecular_function	thiamine pyrophosphate binding
C	0042802	molecular_function	identical protein binding
C	0046296	biological_process	glycolate catabolic process
C	0050660	molecular_function	flavin adenine dinucleotide binding
C	0071949	molecular_function	FAD binding
D	0000287	molecular_function	magnesium ion binding
D	0003824	molecular_function	catalytic activity
D	0005948	cellular_component	acetolactate synthase complex
D	0009028	molecular_function	tartronate-semialdehyde synthase activity
D	0009097	biological_process	isoleucine biosynthetic process
D	0009099	biological_process	L-valine biosynthetic process
D	0009436	biological_process	glyoxylate catabolic process
D	0016829	molecular_function	lyase activity
D	0019752	biological_process	carboxylic acid metabolic process
D	0030976	molecular_function	thiamine pyrophosphate binding
D	0042802	molecular_function	identical protein binding
D	0046296	biological_process	glycolate catabolic process
D	0050660	molecular_function	flavin adenine dinucleotide binding
D	0071949	molecular_function	FAD binding
E	0000287	molecular_function	magnesium ion binding
E	0003824	molecular_function	catalytic activity
E	0005948	cellular_component	acetolactate synthase complex
E	0009028	molecular_function	tartronate-semialdehyde synthase activity
E	0009097	biological_process	isoleucine biosynthetic process
E	0009099	biological_process	L-valine biosynthetic process
E	0009436	biological_process	glyoxylate catabolic process
E	0016829	molecular_function	lyase activity
E	0019752	biological_process	carboxylic acid metabolic process
E	0030976	molecular_function	thiamine pyrophosphate binding
E	0042802	molecular_function	identical protein binding
E	0046296	biological_process	glycolate catabolic process
E	0050660	molecular_function	flavin adenine dinucleotide binding
E	0071949	molecular_function	FAD binding
F	0000287	molecular_function	magnesium ion binding
F	0003824	molecular_function	catalytic activity
F	0005948	cellular_component	acetolactate synthase complex
F	0009028	molecular_function	tartronate-semialdehyde synthase activity
F	0009097	biological_process	isoleucine biosynthetic process
F	0009099	biological_process	L-valine biosynthetic process
F	0009436	biological_process	glyoxylate catabolic process
F	0016829	molecular_function	lyase activity
F	0019752	biological_process	carboxylic acid metabolic process
F	0030976	molecular_function	thiamine pyrophosphate binding
F	0042802	molecular_function	identical protein binding
F	0046296	biological_process	glycolate catabolic process
F	0050660	molecular_function	flavin adenine dinucleotide binding
F	0071949	molecular_function	FAD binding

Catalytic Information from CSA

site_id	MCSA1
Number of Residues	5
Details	M-CSA 298

Chain	Residue	Details
A	VAL25	polar/non-polar interaction
A	VAL51	electrostatic stabiliser, polar/non-polar interaction
A	ILE425	polar/non-polar interaction
A	ARG480	polar/non-polar interaction
A	GLN483	polar/non-polar interaction

---

site_id	MCSA2
Number of Residues	5
Details	M-CSA 298

Chain	Residue	Details
B	VAL25	polar/non-polar interaction
B	VAL51	electrostatic stabiliser, polar/non-polar interaction
B	ILE425	polar/non-polar interaction
B	ARG480	polar/non-polar interaction
B	GLN483	polar/non-polar interaction

---

site_id	MCSA3
Number of Residues	5
Details	M-CSA 298

Chain	Residue	Details
C	VAL25	polar/non-polar interaction
C	VAL51	electrostatic stabiliser, polar/non-polar interaction
C	ILE425	polar/non-polar interaction
C	ARG480	polar/non-polar interaction
C	GLN483	polar/non-polar interaction

---

site_id	MCSA4
Number of Residues	5
Details	M-CSA 298

Chain	Residue	Details
D	VAL25	polar/non-polar interaction
D	VAL51	electrostatic stabiliser, polar/non-polar interaction
D	ILE425	polar/non-polar interaction
D	ARG480	polar/non-polar interaction
D	GLN483	polar/non-polar interaction

---

site_id	MCSA5
Number of Residues	5
Details	M-CSA 298

Chain	Residue	Details
E	VAL25	polar/non-polar interaction
E	VAL51	electrostatic stabiliser, polar/non-polar interaction
E	ILE425	polar/non-polar interaction
E	ARG480	polar/non-polar interaction
E	GLN483	polar/non-polar interaction

---

site_id	MCSA6
Number of Residues	5
Details	M-CSA 298

Chain	Residue	Details
F	VAL25	polar/non-polar interaction
F	VAL51	electrostatic stabiliser, polar/non-polar interaction
F	ILE425	polar/non-polar interaction
F	ARG480	polar/non-polar interaction
F	GLN483	polar/non-polar interaction

---