8BEF

Cryo-EM structure of the Arabidopsis thaliana I+III2 supercomplex (CI membrane core)

Functional Information from GO Data

Chain	GOid	namespace	contents
a	0003674	molecular_function	molecular_function
a	0005739	cellular_component	mitochondrion
a	0005743	cellular_component	mitochondrial inner membrane
a	0045271	cellular_component	respiratory chain complex I
A	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
A	0016651	molecular_function	oxidoreductase activity, acting on NAD(P)H
A	0030964	cellular_component	NADH dehydrogenase complex
A	0031966	cellular_component	mitochondrial membrane
A	0045271	cellular_component	respiratory chain complex I
A	1902600	biological_process	proton transmembrane transport
b	0003674	molecular_function	molecular_function
b	0005739	cellular_component	mitochondrion
b	0005829	cellular_component	cytosol
b	0008150	biological_process	biological_process
d	0000325	cellular_component	plant-type vacuole
d	0003674	molecular_function	molecular_function
d	0005739	cellular_component	mitochondrion
d	0005829	cellular_component	cytosol
d	0008150	biological_process	biological_process
d	0045271	cellular_component	respiratory chain complex I
e	0003674	molecular_function	molecular_function
e	0005739	cellular_component	mitochondrion
e	0005743	cellular_component	mitochondrial inner membrane
e	0005758	cellular_component	mitochondrial intermembrane space
e	0005829	cellular_component	cytosol
e	0032981	biological_process	mitochondrial respiratory chain complex I assembly
e	0045271	cellular_component	respiratory chain complex I
f	0003674	molecular_function	molecular_function
f	0005739	cellular_component	mitochondrion
f	0005829	cellular_component	cytosol
f	0009853	biological_process	photorespiration
f	0031966	cellular_component	mitochondrial membrane
f	0045271	cellular_component	respiratory chain complex I
H	0003674	molecular_function	molecular_function
H	0003954	molecular_function	NADH dehydrogenase activity
H	0005575	cellular_component	cellular_component
H	0005743	cellular_component	mitochondrial inner membrane
H	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
H	0008150	biological_process	biological_process
H	0009060	biological_process	aerobic respiration
H	0016020	cellular_component	membrane
H	0045271	cellular_component	respiratory chain complex I
H	1902600	biological_process	proton transmembrane transport
i	0003674	molecular_function	molecular_function
i	0005739	cellular_component	mitochondrion
i	0009853	biological_process	photorespiration
i	0031966	cellular_component	mitochondrial membrane
i	0045271	cellular_component	respiratory chain complex I
J	0005739	cellular_component	mitochondrion
J	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
J	0031966	cellular_component	mitochondrial membrane
J	0045271	cellular_component	respiratory chain complex I
J	1902600	biological_process	proton transmembrane transport
K	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
K	0009536	cellular_component	plastid
K	0016651	molecular_function	oxidoreductase activity, acting on NAD(P)H
K	0030964	cellular_component	NADH dehydrogenase complex
K	0031966	cellular_component	mitochondrial membrane
K	0042773	biological_process	ATP synthesis coupled electron transport
K	1902600	biological_process	proton transmembrane transport
L	0005743	cellular_component	mitochondrial inner membrane
L	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
L	0009536	cellular_component	plastid
L	0015990	biological_process	electron transport coupled proton transport
L	0042773	biological_process	ATP synthesis coupled electron transport
L	0045271	cellular_component	respiratory chain complex I
M	0003954	molecular_function	NADH dehydrogenase activity
M	0005743	cellular_component	mitochondrial inner membrane
M	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
M	0009060	biological_process	aerobic respiration
M	0009536	cellular_component	plastid
M	0015990	biological_process	electron transport coupled proton transport
M	0042773	biological_process	ATP synthesis coupled electron transport
M	0045271	cellular_component	respiratory chain complex I
M	0048039	molecular_function	ubiquinone binding
N	0003954	molecular_function	NADH dehydrogenase activity
N	0005743	cellular_component	mitochondrial inner membrane
N	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
N	0009536	cellular_component	plastid
N	0022904	biological_process	respiratory electron transport chain
N	0042773	biological_process	ATP synthesis coupled electron transport
N	0045271	cellular_component	respiratory chain complex I
N	0045333	biological_process	cellular respiration
N	1902600	biological_process	proton transmembrane transport
O	0005515	molecular_function	protein binding
O	0005739	cellular_component	mitochondrion
O	0005829	cellular_component	cytosol
O	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
O	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
O	0009055	molecular_function	electron transfer activity
O	0022900	biological_process	electron transport chain
O	0045271	cellular_component	respiratory chain complex I
O	0046872	molecular_function	metal ion binding
O	0051536	molecular_function	iron-sulfur cluster binding
O	0051537	molecular_function	2 iron, 2 sulfur cluster binding
O	0140647	biological_process	P450-containing electron transport chain
O	1902600	biological_process	proton transmembrane transport
v	0000325	cellular_component	plant-type vacuole
v	0005507	molecular_function	copper ion binding
v	0005515	molecular_function	protein binding
v	0005730	cellular_component	nucleolus
v	0005739	cellular_component	mitochondrion
v	0005777	cellular_component	peroxisome
v	0009853	biological_process	photorespiration
v	0031966	cellular_component	mitochondrial membrane
v	0045271	cellular_component	respiratory chain complex I
x	0000325	cellular_component	plant-type vacuole
x	0005515	molecular_function	protein binding
x	0005739	cellular_component	mitochondrion
x	0005829	cellular_component	cytosol
x	0009651	biological_process	response to salt stress
x	0009737	biological_process	response to abscisic acid
x	0009853	biological_process	photorespiration
x	0010228	biological_process	vegetative to reproductive phase transition of meristem
x	0031966	cellular_component	mitochondrial membrane
x	0045271	cellular_component	respiratory chain complex I
x	0046872	molecular_function	metal ion binding
X	0003674	molecular_function	molecular_function
X	0005739	cellular_component	mitochondrion
X	0005758	cellular_component	mitochondrial intermembrane space
X	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
X	0009536	cellular_component	plastid
X	0045271	cellular_component	respiratory chain complex I
y	0004089	molecular_function	carbonate dehydratase activity
y	0005515	molecular_function	protein binding
y	0005634	cellular_component	nucleus
y	0005739	cellular_component	mitochondrion
y	0009853	biological_process	photorespiration
y	0009901	biological_process	anther dehiscence
y	0016829	molecular_function	lyase activity
y	0031966	cellular_component	mitochondrial membrane
y	0042802	molecular_function	identical protein binding
y	0045271	cellular_component	respiratory chain complex I
y	0046872	molecular_function	metal ion binding
y	0070207	biological_process	protein homotrimerization
y	2000377	biological_process	regulation of reactive oxygen species metabolic process
Y	0005739	cellular_component	mitochondrion
Y	0005741	cellular_component	mitochondrial outer membrane
Y	0005743	cellular_component	mitochondrial inner membrane
Y	0005829	cellular_component	cytosol
Y	0006811	biological_process	monoatomic ion transport
Y	0009507	cellular_component	chloroplast
Y	0009527	cellular_component	plastid outer membrane
Y	0009707	cellular_component	chloroplast outer membrane
Y	0015288	molecular_function	porin activity
Y	0042721	cellular_component	TIM22 mitochondrial import inner membrane insertion complex
Y	0042803	molecular_function	protein homodimerization activity
Y	0045039	biological_process	protein insertion into mitochondrial inner membrane
Y	0045271	cellular_component	respiratory chain complex I
Y	0046930	cellular_component	pore complex
Y	0055085	biological_process	transmembrane transport
z	0004089	molecular_function	carbonate dehydratase activity
z	0005634	cellular_component	nucleus
z	0005739	cellular_component	mitochondrion
z	0009853	biological_process	photorespiration
z	0016829	molecular_function	lyase activity
z	0031966	cellular_component	mitochondrial membrane
z	0045271	cellular_component	respiratory chain complex I
z	0046872	molecular_function	metal ion binding
z	0070207	biological_process	protein homotrimerization
Z	0003674	molecular_function	molecular_function
Z	0005576	cellular_component	extracellular region
Z	0005739	cellular_component	mitochondrion
Z	0005743	cellular_component	mitochondrial inner membrane
Z	0009793	biological_process	embryo development ending in seed dormancy
Z	0009853	biological_process	photorespiration
Z	0031966	cellular_component	mitochondrial membrane
Z	0045271	cellular_component	respiratory chain complex I

Functional Information from PROSITE/UniProt

site_id	PS00667
Number of Residues	16
Details	COMPLEX1_ND1_1 Respiratory-chain NADH dehydrogenase subunit 1 signature 1. GLLQpLaDGLKLIlKE

Chain	Residue	Details
H	GLY47-GLU62

---

site_id	PS00668
Number of Residues	14
Details	COMPLEX1_ND1_2 Respiratory-chain NADH dehydrogenase subunit 1 signature 2. PFDLPEAEaeLVa.G

Chain	Residue	Details
H	PRO202-GLY215

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	830
Details	Transmembrane: {"description":"Helical","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	41
Details	Domain: {"description":"CHCH 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU01150","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	38
Details	Domain: {"description":"CHCH 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU01150","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	20
Details	Motif: {"description":"Cx9C motif 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU01150","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	20
Details	Motif: {"description":"Cx9C motif 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU01150","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	10
Details	Motif: {"description":"Cx9C motif 3","evidences":[{"source":"PROSITE-ProRule","id":"PRU01150","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	11
Details	Motif: {"description":"Cx10C motif","evidences":[{"source":"PROSITE-ProRule","id":"PRU01150","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI9
Number of Residues	41
Details	Domain: {"description":"CHCH","evidences":[{"source":"PROSITE-ProRule","id":"PRU01150","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI11
Number of Residues	7
Details	Binding site: {"evidences":[{"evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI12
Number of Residues	42
Details	Transit peptide: {"description":"Mitochondrion","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI13
Number of Residues	14
Details	Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---