8B92
Crystal structure of PPARG and NCOR2 with an inverse agonist (compound SI-2)
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003677 | molecular_function | DNA binding |
| A | 0004879 | molecular_function | nuclear receptor activity |
| A | 0005634 | cellular_component | nucleus |
| A | 0006355 | biological_process | regulation of DNA-templated transcription |
| B | 0003677 | molecular_function | DNA binding |
| B | 0004879 | molecular_function | nuclear receptor activity |
| B | 0005634 | cellular_component | nucleus |
| B | 0006355 | biological_process | regulation of DNA-templated transcription |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 8 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:9744270, ECO:0007744|PDB:2PRG |
| Chain | Residue | Details |
| A | GLN286 | |
| A | HIS323 | |
| A | HIS449 | |
| A | TYR473 | |
| B | GLN286 | |
| B | HIS323 | |
| B | HIS449 | |
| B | TYR473 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:36737649 |
| Chain | Residue | Details |
| A | LYS224 | |
| B | LYS224 |
