8ARI

Cryo-EM structure of human CtBP1/RAI2(303-362) delta(331-341) filament

Functional Information from GO Data

Chain	GOid	namespace	contents
a	0005618	cellular_component	cell wall
A	0000122	biological_process	negative regulation of transcription by RNA polymerase II
A	0001221	molecular_function	transcription coregulator binding
A	0001222	molecular_function	transcription corepressor binding
A	0003682	molecular_function	chromatin binding
A	0003713	molecular_function	transcription coactivator activity
A	0003714	molecular_function	transcription corepressor activity
A	0005515	molecular_function	protein binding
A	0005634	cellular_component	nucleus
A	0005654	cellular_component	nucleoplasm
A	0005737	cellular_component	cytoplasm
A	0006351	biological_process	DNA-templated transcription
A	0006357	biological_process	regulation of transcription by RNA polymerase II
A	0006468	biological_process	protein phosphorylation
A	0008285	biological_process	negative regulation of cell population proliferation
A	0016491	molecular_function	oxidoreductase activity
A	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
A	0017053	cellular_component	transcription repressor complex
A	0019079	biological_process	viral genome replication
A	0019904	molecular_function	protein domain specific binding
A	0030154	biological_process	cell differentiation
A	0042802	molecular_function	identical protein binding
A	0045892	biological_process	negative regulation of DNA-templated transcription
A	0045893	biological_process	positive regulation of DNA-templated transcription
A	0048488	biological_process	synaptic vesicle endocytosis
A	0050872	biological_process	white fat cell differentiation
A	0051287	molecular_function	NAD binding
A	0051726	biological_process	regulation of cell cycle
A	0061629	molecular_function	RNA polymerase II-specific DNA-binding transcription factor binding
A	0097091	biological_process	synaptic vesicle clustering
A	0098831	cellular_component	presynaptic active zone cytoplasmic component
A	0098978	cellular_component	glutamatergic synapse
A	0098982	cellular_component	GABA-ergic synapse
A	0106222	molecular_function	lncRNA binding
A	0140297	molecular_function	DNA-binding transcription factor binding
b	0005618	cellular_component	cell wall
B	0000122	biological_process	negative regulation of transcription by RNA polymerase II
B	0001221	molecular_function	transcription coregulator binding
B	0001222	molecular_function	transcription corepressor binding
B	0003682	molecular_function	chromatin binding
B	0003713	molecular_function	transcription coactivator activity
B	0003714	molecular_function	transcription corepressor activity
B	0005515	molecular_function	protein binding
B	0005634	cellular_component	nucleus
B	0005654	cellular_component	nucleoplasm
B	0005737	cellular_component	cytoplasm
B	0006351	biological_process	DNA-templated transcription
B	0006357	biological_process	regulation of transcription by RNA polymerase II
B	0006468	biological_process	protein phosphorylation
B	0008285	biological_process	negative regulation of cell population proliferation
B	0016491	molecular_function	oxidoreductase activity
B	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
B	0017053	cellular_component	transcription repressor complex
B	0019079	biological_process	viral genome replication
B	0019904	molecular_function	protein domain specific binding
B	0030154	biological_process	cell differentiation
B	0042802	molecular_function	identical protein binding
B	0045892	biological_process	negative regulation of DNA-templated transcription
B	0045893	biological_process	positive regulation of DNA-templated transcription
B	0048488	biological_process	synaptic vesicle endocytosis
B	0050872	biological_process	white fat cell differentiation
B	0051287	molecular_function	NAD binding
B	0051726	biological_process	regulation of cell cycle
B	0061629	molecular_function	RNA polymerase II-specific DNA-binding transcription factor binding
B	0097091	biological_process	synaptic vesicle clustering
B	0098831	cellular_component	presynaptic active zone cytoplasmic component
B	0098978	cellular_component	glutamatergic synapse
B	0098982	cellular_component	GABA-ergic synapse
B	0106222	molecular_function	lncRNA binding
B	0140297	molecular_function	DNA-binding transcription factor binding
c	0005618	cellular_component	cell wall
C	0000122	biological_process	negative regulation of transcription by RNA polymerase II
C	0001221	molecular_function	transcription coregulator binding
C	0001222	molecular_function	transcription corepressor binding
C	0003682	molecular_function	chromatin binding
C	0003713	molecular_function	transcription coactivator activity
C	0003714	molecular_function	transcription corepressor activity
C	0005515	molecular_function	protein binding
C	0005634	cellular_component	nucleus
C	0005654	cellular_component	nucleoplasm
C	0005737	cellular_component	cytoplasm
C	0006351	biological_process	DNA-templated transcription
C	0006357	biological_process	regulation of transcription by RNA polymerase II
C	0006468	biological_process	protein phosphorylation
C	0008285	biological_process	negative regulation of cell population proliferation
C	0016491	molecular_function	oxidoreductase activity
C	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
C	0017053	cellular_component	transcription repressor complex
C	0019079	biological_process	viral genome replication
C	0019904	molecular_function	protein domain specific binding
C	0030154	biological_process	cell differentiation
C	0042802	molecular_function	identical protein binding
C	0045892	biological_process	negative regulation of DNA-templated transcription
C	0045893	biological_process	positive regulation of DNA-templated transcription
C	0048488	biological_process	synaptic vesicle endocytosis
C	0050872	biological_process	white fat cell differentiation
C	0051287	molecular_function	NAD binding
C	0051726	biological_process	regulation of cell cycle
C	0061629	molecular_function	RNA polymerase II-specific DNA-binding transcription factor binding
C	0097091	biological_process	synaptic vesicle clustering
C	0098831	cellular_component	presynaptic active zone cytoplasmic component
C	0098978	cellular_component	glutamatergic synapse
C	0098982	cellular_component	GABA-ergic synapse
C	0106222	molecular_function	lncRNA binding
C	0140297	molecular_function	DNA-binding transcription factor binding
d	0005618	cellular_component	cell wall
D	0000122	biological_process	negative regulation of transcription by RNA polymerase II
D	0001221	molecular_function	transcription coregulator binding
D	0001222	molecular_function	transcription corepressor binding
D	0003682	molecular_function	chromatin binding
D	0003713	molecular_function	transcription coactivator activity
D	0003714	molecular_function	transcription corepressor activity
D	0005515	molecular_function	protein binding
D	0005634	cellular_component	nucleus
D	0005654	cellular_component	nucleoplasm
D	0005737	cellular_component	cytoplasm
D	0006351	biological_process	DNA-templated transcription
D	0006357	biological_process	regulation of transcription by RNA polymerase II
D	0006468	biological_process	protein phosphorylation
D	0008285	biological_process	negative regulation of cell population proliferation
D	0016491	molecular_function	oxidoreductase activity
D	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
D	0017053	cellular_component	transcription repressor complex
D	0019079	biological_process	viral genome replication
D	0019904	molecular_function	protein domain specific binding
D	0030154	biological_process	cell differentiation
D	0042802	molecular_function	identical protein binding
D	0045892	biological_process	negative regulation of DNA-templated transcription
D	0045893	biological_process	positive regulation of DNA-templated transcription
D	0048488	biological_process	synaptic vesicle endocytosis
D	0050872	biological_process	white fat cell differentiation
D	0051287	molecular_function	NAD binding
D	0051726	biological_process	regulation of cell cycle
D	0061629	molecular_function	RNA polymerase II-specific DNA-binding transcription factor binding
D	0097091	biological_process	synaptic vesicle clustering
D	0098831	cellular_component	presynaptic active zone cytoplasmic component
D	0098978	cellular_component	glutamatergic synapse
D	0098982	cellular_component	GABA-ergic synapse
D	0106222	molecular_function	lncRNA binding
D	0140297	molecular_function	DNA-binding transcription factor binding
e	0005618	cellular_component	cell wall
E	0000122	biological_process	negative regulation of transcription by RNA polymerase II
E	0001221	molecular_function	transcription coregulator binding
E	0001222	molecular_function	transcription corepressor binding
E	0003682	molecular_function	chromatin binding
E	0003713	molecular_function	transcription coactivator activity
E	0003714	molecular_function	transcription corepressor activity
E	0005515	molecular_function	protein binding
E	0005634	cellular_component	nucleus
E	0005654	cellular_component	nucleoplasm
E	0005737	cellular_component	cytoplasm
E	0006351	biological_process	DNA-templated transcription
E	0006357	biological_process	regulation of transcription by RNA polymerase II
E	0006468	biological_process	protein phosphorylation
E	0008285	biological_process	negative regulation of cell population proliferation
E	0016491	molecular_function	oxidoreductase activity
E	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
E	0017053	cellular_component	transcription repressor complex
E	0019079	biological_process	viral genome replication
E	0019904	molecular_function	protein domain specific binding
E	0030154	biological_process	cell differentiation
E	0042802	molecular_function	identical protein binding
E	0045892	biological_process	negative regulation of DNA-templated transcription
E	0045893	biological_process	positive regulation of DNA-templated transcription
E	0048488	biological_process	synaptic vesicle endocytosis
E	0050872	biological_process	white fat cell differentiation
E	0051287	molecular_function	NAD binding
E	0051726	biological_process	regulation of cell cycle
E	0061629	molecular_function	RNA polymerase II-specific DNA-binding transcription factor binding
E	0097091	biological_process	synaptic vesicle clustering
E	0098831	cellular_component	presynaptic active zone cytoplasmic component
E	0098978	cellular_component	glutamatergic synapse
E	0098982	cellular_component	GABA-ergic synapse
E	0106222	molecular_function	lncRNA binding
E	0140297	molecular_function	DNA-binding transcription factor binding
f	0005618	cellular_component	cell wall
F	0000122	biological_process	negative regulation of transcription by RNA polymerase II
F	0001221	molecular_function	transcription coregulator binding
F	0001222	molecular_function	transcription corepressor binding
F	0003682	molecular_function	chromatin binding
F	0003713	molecular_function	transcription coactivator activity
F	0003714	molecular_function	transcription corepressor activity
F	0005515	molecular_function	protein binding
F	0005634	cellular_component	nucleus
F	0005654	cellular_component	nucleoplasm
F	0005737	cellular_component	cytoplasm
F	0006351	biological_process	DNA-templated transcription
F	0006357	biological_process	regulation of transcription by RNA polymerase II
F	0006468	biological_process	protein phosphorylation
F	0008285	biological_process	negative regulation of cell population proliferation
F	0016491	molecular_function	oxidoreductase activity
F	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
F	0017053	cellular_component	transcription repressor complex
F	0019079	biological_process	viral genome replication
F	0019904	molecular_function	protein domain specific binding
F	0030154	biological_process	cell differentiation
F	0042802	molecular_function	identical protein binding
F	0045892	biological_process	negative regulation of DNA-templated transcription
F	0045893	biological_process	positive regulation of DNA-templated transcription
F	0048488	biological_process	synaptic vesicle endocytosis
F	0050872	biological_process	white fat cell differentiation
F	0051287	molecular_function	NAD binding
F	0051726	biological_process	regulation of cell cycle
F	0061629	molecular_function	RNA polymerase II-specific DNA-binding transcription factor binding
F	0097091	biological_process	synaptic vesicle clustering
F	0098831	cellular_component	presynaptic active zone cytoplasmic component
F	0098978	cellular_component	glutamatergic synapse
F	0098982	cellular_component	GABA-ergic synapse
F	0106222	molecular_function	lncRNA binding
F	0140297	molecular_function	DNA-binding transcription factor binding
g	0005618	cellular_component	cell wall
G	0000122	biological_process	negative regulation of transcription by RNA polymerase II
G	0001221	molecular_function	transcription coregulator binding
G	0001222	molecular_function	transcription corepressor binding
G	0003682	molecular_function	chromatin binding
G	0003713	molecular_function	transcription coactivator activity
G	0003714	molecular_function	transcription corepressor activity
G	0005515	molecular_function	protein binding
G	0005634	cellular_component	nucleus
G	0005654	cellular_component	nucleoplasm
G	0005737	cellular_component	cytoplasm
G	0006351	biological_process	DNA-templated transcription
G	0006357	biological_process	regulation of transcription by RNA polymerase II
G	0006468	biological_process	protein phosphorylation
G	0008285	biological_process	negative regulation of cell population proliferation
G	0016491	molecular_function	oxidoreductase activity
G	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
G	0017053	cellular_component	transcription repressor complex
G	0019079	biological_process	viral genome replication
G	0019904	molecular_function	protein domain specific binding
G	0030154	biological_process	cell differentiation
G	0042802	molecular_function	identical protein binding
G	0045892	biological_process	negative regulation of DNA-templated transcription
G	0045893	biological_process	positive regulation of DNA-templated transcription
G	0048488	biological_process	synaptic vesicle endocytosis
G	0050872	biological_process	white fat cell differentiation
G	0051287	molecular_function	NAD binding
G	0051726	biological_process	regulation of cell cycle
G	0061629	molecular_function	RNA polymerase II-specific DNA-binding transcription factor binding
G	0097091	biological_process	synaptic vesicle clustering
G	0098831	cellular_component	presynaptic active zone cytoplasmic component
G	0098978	cellular_component	glutamatergic synapse
G	0098982	cellular_component	GABA-ergic synapse
G	0106222	molecular_function	lncRNA binding
G	0140297	molecular_function	DNA-binding transcription factor binding
h	0005618	cellular_component	cell wall
H	0000122	biological_process	negative regulation of transcription by RNA polymerase II
H	0001221	molecular_function	transcription coregulator binding
H	0001222	molecular_function	transcription corepressor binding
H	0003682	molecular_function	chromatin binding
H	0003713	molecular_function	transcription coactivator activity
H	0003714	molecular_function	transcription corepressor activity
H	0005515	molecular_function	protein binding
H	0005634	cellular_component	nucleus
H	0005654	cellular_component	nucleoplasm
H	0005737	cellular_component	cytoplasm
H	0006351	biological_process	DNA-templated transcription
H	0006357	biological_process	regulation of transcription by RNA polymerase II
H	0006468	biological_process	protein phosphorylation
H	0008285	biological_process	negative regulation of cell population proliferation
H	0016491	molecular_function	oxidoreductase activity
H	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
H	0017053	cellular_component	transcription repressor complex
H	0019079	biological_process	viral genome replication
H	0019904	molecular_function	protein domain specific binding
H	0030154	biological_process	cell differentiation
H	0042802	molecular_function	identical protein binding
H	0045892	biological_process	negative regulation of DNA-templated transcription
H	0045893	biological_process	positive regulation of DNA-templated transcription
H	0048488	biological_process	synaptic vesicle endocytosis
H	0050872	biological_process	white fat cell differentiation
H	0051287	molecular_function	NAD binding
H	0051726	biological_process	regulation of cell cycle
H	0061629	molecular_function	RNA polymerase II-specific DNA-binding transcription factor binding
H	0097091	biological_process	synaptic vesicle clustering
H	0098831	cellular_component	presynaptic active zone cytoplasmic component
H	0098978	cellular_component	glutamatergic synapse
H	0098982	cellular_component	GABA-ergic synapse
H	0106222	molecular_function	lncRNA binding
H	0140297	molecular_function	DNA-binding transcription factor binding
i	0005618	cellular_component	cell wall
I	0000122	biological_process	negative regulation of transcription by RNA polymerase II
I	0001221	molecular_function	transcription coregulator binding
I	0001222	molecular_function	transcription corepressor binding
I	0003682	molecular_function	chromatin binding
I	0003713	molecular_function	transcription coactivator activity
I	0003714	molecular_function	transcription corepressor activity
I	0005515	molecular_function	protein binding
I	0005634	cellular_component	nucleus
I	0005654	cellular_component	nucleoplasm
I	0005737	cellular_component	cytoplasm
I	0006351	biological_process	DNA-templated transcription
I	0006357	biological_process	regulation of transcription by RNA polymerase II
I	0006468	biological_process	protein phosphorylation
I	0008285	biological_process	negative regulation of cell population proliferation
I	0016491	molecular_function	oxidoreductase activity
I	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
I	0017053	cellular_component	transcription repressor complex
I	0019079	biological_process	viral genome replication
I	0019904	molecular_function	protein domain specific binding
I	0030154	biological_process	cell differentiation
I	0042802	molecular_function	identical protein binding
I	0045892	biological_process	negative regulation of DNA-templated transcription
I	0045893	biological_process	positive regulation of DNA-templated transcription
I	0048488	biological_process	synaptic vesicle endocytosis
I	0050872	biological_process	white fat cell differentiation
I	0051287	molecular_function	NAD binding
I	0051726	biological_process	regulation of cell cycle
I	0061629	molecular_function	RNA polymerase II-specific DNA-binding transcription factor binding
I	0097091	biological_process	synaptic vesicle clustering
I	0098831	cellular_component	presynaptic active zone cytoplasmic component
I	0098978	cellular_component	glutamatergic synapse
I	0098982	cellular_component	GABA-ergic synapse
I	0106222	molecular_function	lncRNA binding
I	0140297	molecular_function	DNA-binding transcription factor binding
j	0005618	cellular_component	cell wall
J	0000122	biological_process	negative regulation of transcription by RNA polymerase II
J	0001221	molecular_function	transcription coregulator binding
J	0001222	molecular_function	transcription corepressor binding
J	0003682	molecular_function	chromatin binding
J	0003713	molecular_function	transcription coactivator activity
J	0003714	molecular_function	transcription corepressor activity
J	0005515	molecular_function	protein binding
J	0005634	cellular_component	nucleus
J	0005654	cellular_component	nucleoplasm
J	0005737	cellular_component	cytoplasm
J	0006351	biological_process	DNA-templated transcription
J	0006357	biological_process	regulation of transcription by RNA polymerase II
J	0006468	biological_process	protein phosphorylation
J	0008285	biological_process	negative regulation of cell population proliferation
J	0016491	molecular_function	oxidoreductase activity
J	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
J	0017053	cellular_component	transcription repressor complex
J	0019079	biological_process	viral genome replication
J	0019904	molecular_function	protein domain specific binding
J	0030154	biological_process	cell differentiation
J	0042802	molecular_function	identical protein binding
J	0045892	biological_process	negative regulation of DNA-templated transcription
J	0045893	biological_process	positive regulation of DNA-templated transcription
J	0048488	biological_process	synaptic vesicle endocytosis
J	0050872	biological_process	white fat cell differentiation
J	0051287	molecular_function	NAD binding
J	0051726	biological_process	regulation of cell cycle
J	0061629	molecular_function	RNA polymerase II-specific DNA-binding transcription factor binding
J	0097091	biological_process	synaptic vesicle clustering
J	0098831	cellular_component	presynaptic active zone cytoplasmic component
J	0098978	cellular_component	glutamatergic synapse
J	0098982	cellular_component	GABA-ergic synapse
J	0106222	molecular_function	lncRNA binding
J	0140297	molecular_function	DNA-binding transcription factor binding
K	0000122	biological_process	negative regulation of transcription by RNA polymerase II
K	0001221	molecular_function	transcription coregulator binding
K	0001222	molecular_function	transcription corepressor binding
K	0003682	molecular_function	chromatin binding
K	0003713	molecular_function	transcription coactivator activity
K	0003714	molecular_function	transcription corepressor activity
K	0005515	molecular_function	protein binding
K	0005634	cellular_component	nucleus
K	0005654	cellular_component	nucleoplasm
K	0005737	cellular_component	cytoplasm
K	0006351	biological_process	DNA-templated transcription
K	0006357	biological_process	regulation of transcription by RNA polymerase II
K	0006468	biological_process	protein phosphorylation
K	0008285	biological_process	negative regulation of cell population proliferation
K	0016491	molecular_function	oxidoreductase activity
K	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
K	0017053	cellular_component	transcription repressor complex
K	0019079	biological_process	viral genome replication
K	0019904	molecular_function	protein domain specific binding
K	0030154	biological_process	cell differentiation
K	0042802	molecular_function	identical protein binding
K	0045892	biological_process	negative regulation of DNA-templated transcription
K	0045893	biological_process	positive regulation of DNA-templated transcription
K	0048488	biological_process	synaptic vesicle endocytosis
K	0050872	biological_process	white fat cell differentiation
K	0051287	molecular_function	NAD binding
K	0051726	biological_process	regulation of cell cycle
K	0061629	molecular_function	RNA polymerase II-specific DNA-binding transcription factor binding
K	0097091	biological_process	synaptic vesicle clustering
K	0098831	cellular_component	presynaptic active zone cytoplasmic component
K	0098978	cellular_component	glutamatergic synapse
K	0098982	cellular_component	GABA-ergic synapse
K	0106222	molecular_function	lncRNA binding
K	0140297	molecular_function	DNA-binding transcription factor binding
L	0000122	biological_process	negative regulation of transcription by RNA polymerase II
L	0001221	molecular_function	transcription coregulator binding
L	0001222	molecular_function	transcription corepressor binding
L	0003682	molecular_function	chromatin binding
L	0003713	molecular_function	transcription coactivator activity
L	0003714	molecular_function	transcription corepressor activity
L	0005515	molecular_function	protein binding
L	0005634	cellular_component	nucleus
L	0005654	cellular_component	nucleoplasm
L	0005737	cellular_component	cytoplasm
L	0006351	biological_process	DNA-templated transcription
L	0006357	biological_process	regulation of transcription by RNA polymerase II
L	0006468	biological_process	protein phosphorylation
L	0008285	biological_process	negative regulation of cell population proliferation
L	0016491	molecular_function	oxidoreductase activity
L	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
L	0017053	cellular_component	transcription repressor complex
L	0019079	biological_process	viral genome replication
L	0019904	molecular_function	protein domain specific binding
L	0030154	biological_process	cell differentiation
L	0042802	molecular_function	identical protein binding
L	0045892	biological_process	negative regulation of DNA-templated transcription
L	0045893	biological_process	positive regulation of DNA-templated transcription
L	0048488	biological_process	synaptic vesicle endocytosis
L	0050872	biological_process	white fat cell differentiation
L	0051287	molecular_function	NAD binding
L	0051726	biological_process	regulation of cell cycle
L	0061629	molecular_function	RNA polymerase II-specific DNA-binding transcription factor binding
L	0097091	biological_process	synaptic vesicle clustering
L	0098831	cellular_component	presynaptic active zone cytoplasmic component
L	0098978	cellular_component	glutamatergic synapse
L	0098982	cellular_component	GABA-ergic synapse
L	0106222	molecular_function	lncRNA binding
L	0140297	molecular_function	DNA-binding transcription factor binding
M	0000122	biological_process	negative regulation of transcription by RNA polymerase II
M	0001221	molecular_function	transcription coregulator binding
M	0001222	molecular_function	transcription corepressor binding
M	0003682	molecular_function	chromatin binding
M	0003713	molecular_function	transcription coactivator activity
M	0003714	molecular_function	transcription corepressor activity
M	0005515	molecular_function	protein binding
M	0005634	cellular_component	nucleus
M	0005654	cellular_component	nucleoplasm
M	0005737	cellular_component	cytoplasm
M	0006351	biological_process	DNA-templated transcription
M	0006357	biological_process	regulation of transcription by RNA polymerase II
M	0006468	biological_process	protein phosphorylation
M	0008285	biological_process	negative regulation of cell population proliferation
M	0016491	molecular_function	oxidoreductase activity
M	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
M	0017053	cellular_component	transcription repressor complex
M	0019079	biological_process	viral genome replication
M	0019904	molecular_function	protein domain specific binding
M	0030154	biological_process	cell differentiation
M	0042802	molecular_function	identical protein binding
M	0045892	biological_process	negative regulation of DNA-templated transcription
M	0045893	biological_process	positive regulation of DNA-templated transcription
M	0048488	biological_process	synaptic vesicle endocytosis
M	0050872	biological_process	white fat cell differentiation
M	0051287	molecular_function	NAD binding
M	0051726	biological_process	regulation of cell cycle
M	0061629	molecular_function	RNA polymerase II-specific DNA-binding transcription factor binding
M	0097091	biological_process	synaptic vesicle clustering
M	0098831	cellular_component	presynaptic active zone cytoplasmic component
M	0098978	cellular_component	glutamatergic synapse
M	0098982	cellular_component	GABA-ergic synapse
M	0106222	molecular_function	lncRNA binding
M	0140297	molecular_function	DNA-binding transcription factor binding
N	0000122	biological_process	negative regulation of transcription by RNA polymerase II
N	0001221	molecular_function	transcription coregulator binding
N	0001222	molecular_function	transcription corepressor binding
N	0003682	molecular_function	chromatin binding
N	0003713	molecular_function	transcription coactivator activity
N	0003714	molecular_function	transcription corepressor activity
N	0005515	molecular_function	protein binding
N	0005634	cellular_component	nucleus
N	0005654	cellular_component	nucleoplasm
N	0005737	cellular_component	cytoplasm
N	0006351	biological_process	DNA-templated transcription
N	0006357	biological_process	regulation of transcription by RNA polymerase II
N	0006468	biological_process	protein phosphorylation
N	0008285	biological_process	negative regulation of cell population proliferation
N	0016491	molecular_function	oxidoreductase activity
N	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
N	0017053	cellular_component	transcription repressor complex
N	0019079	biological_process	viral genome replication
N	0019904	molecular_function	protein domain specific binding
N	0030154	biological_process	cell differentiation
N	0042802	molecular_function	identical protein binding
N	0045892	biological_process	negative regulation of DNA-templated transcription
N	0045893	biological_process	positive regulation of DNA-templated transcription
N	0048488	biological_process	synaptic vesicle endocytosis
N	0050872	biological_process	white fat cell differentiation
N	0051287	molecular_function	NAD binding
N	0051726	biological_process	regulation of cell cycle
N	0061629	molecular_function	RNA polymerase II-specific DNA-binding transcription factor binding
N	0097091	biological_process	synaptic vesicle clustering
N	0098831	cellular_component	presynaptic active zone cytoplasmic component
N	0098978	cellular_component	glutamatergic synapse
N	0098982	cellular_component	GABA-ergic synapse
N	0106222	molecular_function	lncRNA binding
N	0140297	molecular_function	DNA-binding transcription factor binding
O	0000122	biological_process	negative regulation of transcription by RNA polymerase II
O	0001221	molecular_function	transcription coregulator binding
O	0001222	molecular_function	transcription corepressor binding
O	0003682	molecular_function	chromatin binding
O	0003713	molecular_function	transcription coactivator activity
O	0003714	molecular_function	transcription corepressor activity
O	0005515	molecular_function	protein binding
O	0005634	cellular_component	nucleus
O	0005654	cellular_component	nucleoplasm
O	0005737	cellular_component	cytoplasm
O	0006351	biological_process	DNA-templated transcription
O	0006357	biological_process	regulation of transcription by RNA polymerase II
O	0006468	biological_process	protein phosphorylation
O	0008285	biological_process	negative regulation of cell population proliferation
O	0016491	molecular_function	oxidoreductase activity
O	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
O	0017053	cellular_component	transcription repressor complex
O	0019079	biological_process	viral genome replication
O	0019904	molecular_function	protein domain specific binding
O	0030154	biological_process	cell differentiation
O	0042802	molecular_function	identical protein binding
O	0045892	biological_process	negative regulation of DNA-templated transcription
O	0045893	biological_process	positive regulation of DNA-templated transcription
O	0048488	biological_process	synaptic vesicle endocytosis
O	0050872	biological_process	white fat cell differentiation
O	0051287	molecular_function	NAD binding
O	0051726	biological_process	regulation of cell cycle
O	0061629	molecular_function	RNA polymerase II-specific DNA-binding transcription factor binding
O	0097091	biological_process	synaptic vesicle clustering
O	0098831	cellular_component	presynaptic active zone cytoplasmic component
O	0098978	cellular_component	glutamatergic synapse
O	0098982	cellular_component	GABA-ergic synapse
O	0106222	molecular_function	lncRNA binding
O	0140297	molecular_function	DNA-binding transcription factor binding
P	0000122	biological_process	negative regulation of transcription by RNA polymerase II
P	0001221	molecular_function	transcription coregulator binding
P	0001222	molecular_function	transcription corepressor binding
P	0003682	molecular_function	chromatin binding
P	0003713	molecular_function	transcription coactivator activity
P	0003714	molecular_function	transcription corepressor activity
P	0005515	molecular_function	protein binding
P	0005634	cellular_component	nucleus
P	0005654	cellular_component	nucleoplasm
P	0005737	cellular_component	cytoplasm
P	0006351	biological_process	DNA-templated transcription
P	0006357	biological_process	regulation of transcription by RNA polymerase II
P	0006468	biological_process	protein phosphorylation
P	0008285	biological_process	negative regulation of cell population proliferation
P	0016491	molecular_function	oxidoreductase activity
P	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
P	0017053	cellular_component	transcription repressor complex
P	0019079	biological_process	viral genome replication
P	0019904	molecular_function	protein domain specific binding
P	0030154	biological_process	cell differentiation
P	0042802	molecular_function	identical protein binding
P	0045892	biological_process	negative regulation of DNA-templated transcription
P	0045893	biological_process	positive regulation of DNA-templated transcription
P	0048488	biological_process	synaptic vesicle endocytosis
P	0050872	biological_process	white fat cell differentiation
P	0051287	molecular_function	NAD binding
P	0051726	biological_process	regulation of cell cycle
P	0061629	molecular_function	RNA polymerase II-specific DNA-binding transcription factor binding
P	0097091	biological_process	synaptic vesicle clustering
P	0098831	cellular_component	presynaptic active zone cytoplasmic component
P	0098978	cellular_component	glutamatergic synapse
P	0098982	cellular_component	GABA-ergic synapse
P	0106222	molecular_function	lncRNA binding
P	0140297	molecular_function	DNA-binding transcription factor binding
Q	0000122	biological_process	negative regulation of transcription by RNA polymerase II
Q	0001221	molecular_function	transcription coregulator binding
Q	0001222	molecular_function	transcription corepressor binding
Q	0003682	molecular_function	chromatin binding
Q	0003713	molecular_function	transcription coactivator activity
Q	0003714	molecular_function	transcription corepressor activity
Q	0005515	molecular_function	protein binding
Q	0005634	cellular_component	nucleus
Q	0005654	cellular_component	nucleoplasm
Q	0005737	cellular_component	cytoplasm
Q	0006351	biological_process	DNA-templated transcription
Q	0006357	biological_process	regulation of transcription by RNA polymerase II
Q	0006468	biological_process	protein phosphorylation
Q	0008285	biological_process	negative regulation of cell population proliferation
Q	0016491	molecular_function	oxidoreductase activity
Q	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
Q	0017053	cellular_component	transcription repressor complex
Q	0019079	biological_process	viral genome replication
Q	0019904	molecular_function	protein domain specific binding
Q	0030154	biological_process	cell differentiation
Q	0042802	molecular_function	identical protein binding
Q	0045892	biological_process	negative regulation of DNA-templated transcription
Q	0045893	biological_process	positive regulation of DNA-templated transcription
Q	0048488	biological_process	synaptic vesicle endocytosis
Q	0050872	biological_process	white fat cell differentiation
Q	0051287	molecular_function	NAD binding
Q	0051726	biological_process	regulation of cell cycle
Q	0061629	molecular_function	RNA polymerase II-specific DNA-binding transcription factor binding
Q	0097091	biological_process	synaptic vesicle clustering
Q	0098831	cellular_component	presynaptic active zone cytoplasmic component
Q	0098978	cellular_component	glutamatergic synapse
Q	0098982	cellular_component	GABA-ergic synapse
Q	0106222	molecular_function	lncRNA binding
Q	0140297	molecular_function	DNA-binding transcription factor binding
R	0000122	biological_process	negative regulation of transcription by RNA polymerase II
R	0001221	molecular_function	transcription coregulator binding
R	0001222	molecular_function	transcription corepressor binding
R	0003682	molecular_function	chromatin binding
R	0003713	molecular_function	transcription coactivator activity
R	0003714	molecular_function	transcription corepressor activity
R	0005515	molecular_function	protein binding
R	0005634	cellular_component	nucleus
R	0005654	cellular_component	nucleoplasm
R	0005737	cellular_component	cytoplasm
R	0006351	biological_process	DNA-templated transcription
R	0006357	biological_process	regulation of transcription by RNA polymerase II
R	0006468	biological_process	protein phosphorylation
R	0008285	biological_process	negative regulation of cell population proliferation
R	0016491	molecular_function	oxidoreductase activity
R	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
R	0017053	cellular_component	transcription repressor complex
R	0019079	biological_process	viral genome replication
R	0019904	molecular_function	protein domain specific binding
R	0030154	biological_process	cell differentiation
R	0042802	molecular_function	identical protein binding
R	0045892	biological_process	negative regulation of DNA-templated transcription
R	0045893	biological_process	positive regulation of DNA-templated transcription
R	0048488	biological_process	synaptic vesicle endocytosis
R	0050872	biological_process	white fat cell differentiation
R	0051287	molecular_function	NAD binding
R	0051726	biological_process	regulation of cell cycle
R	0061629	molecular_function	RNA polymerase II-specific DNA-binding transcription factor binding
R	0097091	biological_process	synaptic vesicle clustering
R	0098831	cellular_component	presynaptic active zone cytoplasmic component
R	0098978	cellular_component	glutamatergic synapse
R	0098982	cellular_component	GABA-ergic synapse
R	0106222	molecular_function	lncRNA binding
R	0140297	molecular_function	DNA-binding transcription factor binding
S	0000122	biological_process	negative regulation of transcription by RNA polymerase II
S	0001221	molecular_function	transcription coregulator binding
S	0001222	molecular_function	transcription corepressor binding
S	0003682	molecular_function	chromatin binding
S	0003713	molecular_function	transcription coactivator activity
S	0003714	molecular_function	transcription corepressor activity
S	0005515	molecular_function	protein binding
S	0005634	cellular_component	nucleus
S	0005654	cellular_component	nucleoplasm
S	0005737	cellular_component	cytoplasm
S	0006351	biological_process	DNA-templated transcription
S	0006357	biological_process	regulation of transcription by RNA polymerase II
S	0006468	biological_process	protein phosphorylation
S	0008285	biological_process	negative regulation of cell population proliferation
S	0016491	molecular_function	oxidoreductase activity
S	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
S	0017053	cellular_component	transcription repressor complex
S	0019079	biological_process	viral genome replication
S	0019904	molecular_function	protein domain specific binding
S	0030154	biological_process	cell differentiation
S	0042802	molecular_function	identical protein binding
S	0045892	biological_process	negative regulation of DNA-templated transcription
S	0045893	biological_process	positive regulation of DNA-templated transcription
S	0048488	biological_process	synaptic vesicle endocytosis
S	0050872	biological_process	white fat cell differentiation
S	0051287	molecular_function	NAD binding
S	0051726	biological_process	regulation of cell cycle
S	0061629	molecular_function	RNA polymerase II-specific DNA-binding transcription factor binding
S	0097091	biological_process	synaptic vesicle clustering
S	0098831	cellular_component	presynaptic active zone cytoplasmic component
S	0098978	cellular_component	glutamatergic synapse
S	0098982	cellular_component	GABA-ergic synapse
S	0106222	molecular_function	lncRNA binding
S	0140297	molecular_function	DNA-binding transcription factor binding
T	0000122	biological_process	negative regulation of transcription by RNA polymerase II
T	0001221	molecular_function	transcription coregulator binding
T	0001222	molecular_function	transcription corepressor binding
T	0003682	molecular_function	chromatin binding
T	0003713	molecular_function	transcription coactivator activity
T	0003714	molecular_function	transcription corepressor activity
T	0005515	molecular_function	protein binding
T	0005634	cellular_component	nucleus
T	0005654	cellular_component	nucleoplasm
T	0005737	cellular_component	cytoplasm
T	0006351	biological_process	DNA-templated transcription
T	0006357	biological_process	regulation of transcription by RNA polymerase II
T	0006468	biological_process	protein phosphorylation
T	0008285	biological_process	negative regulation of cell population proliferation
T	0016491	molecular_function	oxidoreductase activity
T	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
T	0017053	cellular_component	transcription repressor complex
T	0019079	biological_process	viral genome replication
T	0019904	molecular_function	protein domain specific binding
T	0030154	biological_process	cell differentiation
T	0042802	molecular_function	identical protein binding
T	0045892	biological_process	negative regulation of DNA-templated transcription
T	0045893	biological_process	positive regulation of DNA-templated transcription
T	0048488	biological_process	synaptic vesicle endocytosis
T	0050872	biological_process	white fat cell differentiation
T	0051287	molecular_function	NAD binding
T	0051726	biological_process	regulation of cell cycle
T	0061629	molecular_function	RNA polymerase II-specific DNA-binding transcription factor binding
T	0097091	biological_process	synaptic vesicle clustering
T	0098831	cellular_component	presynaptic active zone cytoplasmic component
T	0098978	cellular_component	glutamatergic synapse
T	0098982	cellular_component	GABA-ergic synapse
T	0106222	molecular_function	lncRNA binding
T	0140297	molecular_function	DNA-binding transcription factor binding
U	0000122	biological_process	negative regulation of transcription by RNA polymerase II
U	0001221	molecular_function	transcription coregulator binding
U	0001222	molecular_function	transcription corepressor binding
U	0003682	molecular_function	chromatin binding
U	0003713	molecular_function	transcription coactivator activity
U	0003714	molecular_function	transcription corepressor activity
U	0005515	molecular_function	protein binding
U	0005634	cellular_component	nucleus
U	0005654	cellular_component	nucleoplasm
U	0005737	cellular_component	cytoplasm
U	0006351	biological_process	DNA-templated transcription
U	0006357	biological_process	regulation of transcription by RNA polymerase II
U	0006468	biological_process	protein phosphorylation
U	0008285	biological_process	negative regulation of cell population proliferation
U	0016491	molecular_function	oxidoreductase activity
U	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
U	0017053	cellular_component	transcription repressor complex
U	0019079	biological_process	viral genome replication
U	0019904	molecular_function	protein domain specific binding
U	0030154	biological_process	cell differentiation
U	0042802	molecular_function	identical protein binding
U	0045892	biological_process	negative regulation of DNA-templated transcription
U	0045893	biological_process	positive regulation of DNA-templated transcription
U	0048488	biological_process	synaptic vesicle endocytosis
U	0050872	biological_process	white fat cell differentiation
U	0051287	molecular_function	NAD binding
U	0051726	biological_process	regulation of cell cycle
U	0061629	molecular_function	RNA polymerase II-specific DNA-binding transcription factor binding
U	0097091	biological_process	synaptic vesicle clustering
U	0098831	cellular_component	presynaptic active zone cytoplasmic component
U	0098978	cellular_component	glutamatergic synapse
U	0098982	cellular_component	GABA-ergic synapse
U	0106222	molecular_function	lncRNA binding
U	0140297	molecular_function	DNA-binding transcription factor binding
V	0000122	biological_process	negative regulation of transcription by RNA polymerase II
V	0001221	molecular_function	transcription coregulator binding
V	0001222	molecular_function	transcription corepressor binding
V	0003682	molecular_function	chromatin binding
V	0003713	molecular_function	transcription coactivator activity
V	0003714	molecular_function	transcription corepressor activity
V	0005515	molecular_function	protein binding
V	0005634	cellular_component	nucleus
V	0005654	cellular_component	nucleoplasm
V	0005737	cellular_component	cytoplasm
V	0006351	biological_process	DNA-templated transcription
V	0006357	biological_process	regulation of transcription by RNA polymerase II
V	0006468	biological_process	protein phosphorylation
V	0008285	biological_process	negative regulation of cell population proliferation
V	0016491	molecular_function	oxidoreductase activity
V	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
V	0017053	cellular_component	transcription repressor complex
V	0019079	biological_process	viral genome replication
V	0019904	molecular_function	protein domain specific binding
V	0030154	biological_process	cell differentiation
V	0042802	molecular_function	identical protein binding
V	0045892	biological_process	negative regulation of DNA-templated transcription
V	0045893	biological_process	positive regulation of DNA-templated transcription
V	0048488	biological_process	synaptic vesicle endocytosis
V	0050872	biological_process	white fat cell differentiation
V	0051287	molecular_function	NAD binding
V	0051726	biological_process	regulation of cell cycle
V	0061629	molecular_function	RNA polymerase II-specific DNA-binding transcription factor binding
V	0097091	biological_process	synaptic vesicle clustering
V	0098831	cellular_component	presynaptic active zone cytoplasmic component
V	0098978	cellular_component	glutamatergic synapse
V	0098982	cellular_component	GABA-ergic synapse
V	0106222	molecular_function	lncRNA binding
V	0140297	molecular_function	DNA-binding transcription factor binding
W	0000122	biological_process	negative regulation of transcription by RNA polymerase II
W	0001221	molecular_function	transcription coregulator binding
W	0001222	molecular_function	transcription corepressor binding
W	0003682	molecular_function	chromatin binding
W	0003713	molecular_function	transcription coactivator activity
W	0003714	molecular_function	transcription corepressor activity
W	0005515	molecular_function	protein binding
W	0005634	cellular_component	nucleus
W	0005654	cellular_component	nucleoplasm
W	0005737	cellular_component	cytoplasm
W	0006351	biological_process	DNA-templated transcription
W	0006357	biological_process	regulation of transcription by RNA polymerase II
W	0006468	biological_process	protein phosphorylation
W	0008285	biological_process	negative regulation of cell population proliferation
W	0016491	molecular_function	oxidoreductase activity
W	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
W	0017053	cellular_component	transcription repressor complex
W	0019079	biological_process	viral genome replication
W	0019904	molecular_function	protein domain specific binding
W	0030154	biological_process	cell differentiation
W	0042802	molecular_function	identical protein binding
W	0045892	biological_process	negative regulation of DNA-templated transcription
W	0045893	biological_process	positive regulation of DNA-templated transcription
W	0048488	biological_process	synaptic vesicle endocytosis
W	0050872	biological_process	white fat cell differentiation
W	0051287	molecular_function	NAD binding
W	0051726	biological_process	regulation of cell cycle
W	0061629	molecular_function	RNA polymerase II-specific DNA-binding transcription factor binding
W	0097091	biological_process	synaptic vesicle clustering
W	0098831	cellular_component	presynaptic active zone cytoplasmic component
W	0098978	cellular_component	glutamatergic synapse
W	0098982	cellular_component	GABA-ergic synapse
W	0106222	molecular_function	lncRNA binding
W	0140297	molecular_function	DNA-binding transcription factor binding
X	0000122	biological_process	negative regulation of transcription by RNA polymerase II
X	0001221	molecular_function	transcription coregulator binding
X	0001222	molecular_function	transcription corepressor binding
X	0003682	molecular_function	chromatin binding
X	0003713	molecular_function	transcription coactivator activity
X	0003714	molecular_function	transcription corepressor activity
X	0005515	molecular_function	protein binding
X	0005634	cellular_component	nucleus
X	0005654	cellular_component	nucleoplasm
X	0005737	cellular_component	cytoplasm
X	0006351	biological_process	DNA-templated transcription
X	0006357	biological_process	regulation of transcription by RNA polymerase II
X	0006468	biological_process	protein phosphorylation
X	0008285	biological_process	negative regulation of cell population proliferation
X	0016491	molecular_function	oxidoreductase activity
X	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
X	0017053	cellular_component	transcription repressor complex
X	0019079	biological_process	viral genome replication
X	0019904	molecular_function	protein domain specific binding
X	0030154	biological_process	cell differentiation
X	0042802	molecular_function	identical protein binding
X	0045892	biological_process	negative regulation of DNA-templated transcription
X	0045893	biological_process	positive regulation of DNA-templated transcription
X	0048488	biological_process	synaptic vesicle endocytosis
X	0050872	biological_process	white fat cell differentiation
X	0051287	molecular_function	NAD binding
X	0051726	biological_process	regulation of cell cycle
X	0061629	molecular_function	RNA polymerase II-specific DNA-binding transcription factor binding
X	0097091	biological_process	synaptic vesicle clustering
X	0098831	cellular_component	presynaptic active zone cytoplasmic component
X	0098978	cellular_component	glutamatergic synapse
X	0098982	cellular_component	GABA-ergic synapse
X	0106222	molecular_function	lncRNA binding
X	0140297	molecular_function	DNA-binding transcription factor binding

Functional Information from PROSITE/UniProt

site_id	PS00065
Number of Residues	28
Details	D_2_HYDROXYACID_DH_1 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. LGIIGlGRVGqavalrakafgfn.VLfYD

Chain	Residue	Details
A	LEU177-ASP204

---

site_id	PS00671
Number of Residues	17
Details	D_2_HYDROXYACID_DH_3 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. MRqGaFLVNtARGgLVD

Chain	Residue	Details
A	MET255-ASP271

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	48
Details	Active site: {"evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	24
Details	Active site: {"description":"Proton donor","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	456
Details	Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	24
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"17525332","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---