8AQ3

In surfo structure of the membrane integral lipoprotein N-acyltransferase Lnt from E. coli in complex with PE

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005515	molecular_function	protein binding
A	0005886	cellular_component	plasma membrane
A	0016020	cellular_component	membrane
A	0016410	molecular_function	N-acyltransferase activity
A	0016740	molecular_function	transferase activity
A	0016746	molecular_function	acyltransferase activity
A	0030288	cellular_component	outer membrane-bounded periplasmic space
A	0042158	biological_process	lipoprotein biosynthetic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	23
Details	binding site for residue 6OU A 601

Chain	Residue
A	TRP74
A	SER268
A	LYS335
A	VAL339
A	PRO340
A	PHE341
A	GLY342
A	PRO361
A	MET362
A	ALA387
A	TYR388
A	VAL75
A	SER411
A	ASN412
A	ASP413
A	TRP415
A	SER78
A	ILE79
A	LEU143
A	PHE146
A	LYS236
A	TRP237
A	GLU267

---

site_id	AC2
Number of Residues	18
Details	binding site for residue 6OU A 602

Chain	Residue
A	MET1
A	ALA2
A	ARG9
A	CYS23
A	THR25
A	SER29
A	PRO30
A	TYR31
A	ASP32
A	SER70
A	ASN73
A	LYS418
A	SER419
A	TRP423
A	ARG430
A	ILE458
A	HOH702
A	HOH738

---

site_id	AC3
Number of Residues	1
Details	binding site for residue PG5 A 603

Chain	Residue
A	ARG209

---

site_id	AC4
Number of Residues	3
Details	binding site for residue PG5 A 604

Chain	Residue
A	ARG485
A	GOL615
A	GOL616

---

site_id	AC5
Number of Residues	2
Details	binding site for residue PG5 A 605

Chain	Residue
A	GLY258
A	SER261

---

site_id	AC6
Number of Residues	2
Details	binding site for residue PG5 A 606

Chain	Residue
A	LEU347
A	GOL611

---

site_id	AC7
Number of Residues	5
Details	binding site for residue PG6 A 607

Chain	Residue
A	GLU8
A	ARG13
A	LEU47
A	ASN50
A	VAL188

---

site_id	AC8
Number of Residues	2
Details	binding site for residue TRS A 608

Chain	Residue
A	TYR250
A	PHE280

---

site_id	AC9
Number of Residues	1
Details	binding site for residue ACT A 609

Chain	Residue
A	ARG52

---

site_id	AD1
Number of Residues	1
Details	binding site for residue GOL A 610

Chain	Residue
A	GLY87

---

site_id	AD2
Number of Residues	5
Details	binding site for residue GOL A 611

Chain	Residue
A	THR144
A	PRO346
A	PG5606
A	LMT613
A	HOH740

---

site_id	AD3
Number of Residues	2
Details	binding site for residue LMT A 612

Chain	Residue
A	ARG397
A	TRP489

---

site_id	AD4
Number of Residues	4
Details	binding site for residue LMT A 613

Chain	Residue
A	TRP141
A	LEU143
A	GOL611
A	HOH740

---

site_id	AD5
Number of Residues	1
Details	binding site for residue GOL A 614

Chain	Residue
A	HOH746

---

site_id	AD6
Number of Residues	2
Details	binding site for residue GOL A 615

Chain	Residue
A	ARG485
A	PG5604

---

site_id	AD7
Number of Residues	2
Details	binding site for residue GOL A 616

Chain	Residue
A	GLN212
A	PG5604

---

site_id	AD8
Number of Residues	1
Details	binding site for residue LMT A 618

Chain	Residue
A	PHE65

---

site_id	AD9
Number of Residues	1
Details	binding site for residue LMT A 619

Chain	Residue
A	VAL33

---

site_id	AE1
Number of Residues	8
Details	binding site for residue 6OU A 620

Chain	Residue
A	VAL134
A	PHE137
A	GLU394
A	ASN488
A	TRP489
A	TRP492
A	ALA496
A	GLY499

---

site_id	AE2
Number of Residues	2
Details	binding site for residue CL A 621

Chain	Residue
A	ARG289
A	GLY322

---

site_id	AE3
Number of Residues	2
Details	binding site for residue CL A 622

Chain	Residue
A	TRP121
A	ARG193

---

site_id	AE4
Number of Residues	2
Details	binding site for residue CL A 623

Chain	Residue
A	ARG9
A	ARG11

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	15
Details	Topological domain: {"description":"Cytoplasmic","evidences":[{"source":"PubMed","id":"28675161","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"28885614","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	153
Details	Transmembrane: {"description":"Helical","evidences":[{"source":"PubMed","id":"28675161","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	324
Details	Topological domain: {"description":"Periplasmic","evidences":[{"source":"PubMed","id":"28675161","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"28885614","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	249
Details	Domain: {"description":"CN hydrolase","evidences":[{"source":"HAMAP-Rule","id":"MF_01148","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	1
Details	Active site: {"description":"Proton acceptor","evidences":[{"source":"HAMAP-Rule","id":"MF_01148","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"28675161","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	1
Details	Active site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_01148","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"28675161","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	1
Details	Active site: {"description":"Nucleophile","evidences":[{"source":"HAMAP-Rule","id":"MF_01148","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"28675161","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---