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8AHY

X-ray structure of human NCS-1 bound to Ric-8A

Functional Information from GO Data
ChainGOidnamespacecontents
B0005245molecular_functionvoltage-gated calcium channel activity
B0005509molecular_functioncalcium ion binding
B0005515molecular_functionprotein binding
B0005737cellular_componentcytoplasm
B0005794cellular_componentGolgi apparatus
B0005886cellular_componentplasma membrane
B0008048molecular_functioncalcium sensitive guanylate cyclase activator activity
B0010975biological_processregulation of neuron projection development
B0014069cellular_componentpostsynaptic density
B0030424cellular_componentaxon
B0030425cellular_componentdendrite
B0043231cellular_componentintracellular membrane-bounded organelle
B0045202cellular_componentsynapse
B0046872molecular_functionmetal ion binding
B0048471cellular_componentperinuclear region of cytoplasm
B0070588biological_processcalcium ion transmembrane transport
Functional Information from PROSITE/UniProt
site_idPS00018
Number of Residues13
DetailsEF_HAND_1 EF-hand calcium-binding domain. DENKDGRIEfsEF
ChainResidueDetails
BASP73-PHE85
BASP109-MET121
BASP157-PHE169

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues15
DetailsBINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00448
ChainResidueDetails
BASP73
BASN75
BASP77
BARG79
BGLU84
BASP109
BASP111
BASP113
BTYR115
BGLU120
BASP157
BASN159
BASP161
BLYS163
BGLU168

site_idSWS_FT_FI2
Number of Residues1
DetailsBINDING: BINDING => ECO:0000250|UniProtKB:P62168
ChainResidueDetails
BGLU81

site_idSWS_FT_FI3
Number of Residues1
DetailsLIPID: N-myristoyl glycine => ECO:0000269|PubMed:25255805
ChainResidueDetails
BGLY2

221051

PDB entries from 2024-06-12

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