8AHT
Crystal structure of Plasmodium falciparum Ca2+/Calmodulin in complex with melittin
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005509 | molecular_function | calcium ion binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0008047 | molecular_function | enzyme activator activity |
| A | 0020007 | cellular_component | apical complex |
| A | 0030234 | molecular_function | enzyme regulator activity |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0061891 | molecular_function | calcium ion sensor activity |
| B | 0005509 | molecular_function | calcium ion binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0008047 | molecular_function | enzyme activator activity |
| B | 0020007 | cellular_component | apical complex |
| B | 0030234 | molecular_function | enzyme regulator activity |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0061891 | molecular_function | calcium ion sensor activity |
| C | 0005509 | molecular_function | calcium ion binding |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0008047 | molecular_function | enzyme activator activity |
| C | 0020007 | cellular_component | apical complex |
| C | 0030234 | molecular_function | enzyme regulator activity |
| C | 0046872 | molecular_function | metal ion binding |
| C | 0061891 | molecular_function | calcium ion sensor activity |
| D | 0005509 | molecular_function | calcium ion binding |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0008047 | molecular_function | enzyme activator activity |
| D | 0020007 | cellular_component | apical complex |
| D | 0030234 | molecular_function | enzyme regulator activity |
| D | 0046872 | molecular_function | metal ion binding |
| D | 0061891 | molecular_function | calcium ion sensor activity |
| F | 0004860 | molecular_function | protein kinase inhibitor activity |
| F | 0005576 | cellular_component | extracellular region |
| G | 0004860 | molecular_function | protein kinase inhibitor activity |
| G | 0005576 | cellular_component | extracellular region |
| H | 0004860 | molecular_function | protein kinase inhibitor activity |
| H | 0005576 | cellular_component | extracellular region |
| I | 0004860 | molecular_function | protein kinase inhibitor activity |
| I | 0005576 | cellular_component | extracellular region |
Functional Information from PROSITE/UniProt
| site_id | PS00018 |
| Number of Residues | 13 |
| Details | EF_HAND_1 EF-hand calcium-binding domain. DKDGDGTITtkEL |
| Chain | Residue | Details |
| A | ASP20-LEU32 | |
| A | ASP56-PHE68 | |
| A | ASP93-LEU105 | |
| A | ASP129-PHE141 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 140 |
| Details | Domain: {"description":"EF-hand 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00448","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 70 |
| Details | Domain: {"description":"EF-hand 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00448","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 80 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00448","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | Site: {"description":"Important for the flexibility at the center of the helix, flexibility that is important for the stability of the voltage-gated pore","evidences":[{"source":"PubMed","id":"2187536","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"N-formylglycine; partial","evidences":[{"source":"PubMed","id":"5139483","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Glutamine amide","evidences":[{"source":"PubMed","id":"5592400","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
