8AHT
Crystal structure of Plasmodium falciparum Ca2+/Calmodulin in complex with melittin
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005509 | molecular_function | calcium ion binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0008047 | molecular_function | enzyme activator activity |
| A | 0020007 | cellular_component | apical complex |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0061891 | molecular_function | calcium ion sensor activity |
| B | 0005509 | molecular_function | calcium ion binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0008047 | molecular_function | enzyme activator activity |
| B | 0020007 | cellular_component | apical complex |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0061891 | molecular_function | calcium ion sensor activity |
| C | 0005509 | molecular_function | calcium ion binding |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0008047 | molecular_function | enzyme activator activity |
| C | 0020007 | cellular_component | apical complex |
| C | 0046872 | molecular_function | metal ion binding |
| C | 0061891 | molecular_function | calcium ion sensor activity |
| D | 0005509 | molecular_function | calcium ion binding |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0008047 | molecular_function | enzyme activator activity |
| D | 0020007 | cellular_component | apical complex |
| D | 0046872 | molecular_function | metal ion binding |
| D | 0061891 | molecular_function | calcium ion sensor activity |
| F | 0004860 | molecular_function | protein kinase inhibitor activity |
| F | 0005576 | cellular_component | extracellular region |
| G | 0004860 | molecular_function | protein kinase inhibitor activity |
| G | 0005576 | cellular_component | extracellular region |
| H | 0004860 | molecular_function | protein kinase inhibitor activity |
| H | 0005576 | cellular_component | extracellular region |
| I | 0004860 | molecular_function | protein kinase inhibitor activity |
| I | 0005576 | cellular_component | extracellular region |
Functional Information from PROSITE/UniProt
| site_id | PS00018 |
| Number of Residues | 13 |
| Details | EF_HAND_1 EF-hand calcium-binding domain. DKDGDGTITtkEL |
| Chain | Residue | Details |
| A | ASP20-LEU32 | |
| A | ASP56-PHE68 | |
| A | ASP93-LEU105 | |
| A | ASP129-PHE141 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | SITE: Important for the flexibility at the center of the helix, flexibility that is important for the stability of the voltage-gated pore => ECO:0000269|PubMed:2187536 |
| Chain | Residue | Details |
| F | PRO14 | |
| A | GLU67 | |
| A | ASP93 | |
| A | ASP95 | |
| A | ASP97 | |
| A | TYR99 | |
| A | GLU104 | |
| A | ASP129 | |
| A | ASP131 | |
| A | ASP133 | |
| A | GLN135 | |
| G | PRO14 | |
| A | GLU140 | |
| B | ASP20 | |
| B | ASP22 | |
| B | ASP24 | |
| B | THR26 | |
| B | GLU31 | |
| B | ASP56 | |
| B | ASP58 | |
| B | ASN60 | |
| B | THR62 | |
| H | PRO14 | |
| B | GLU67 | |
| B | ASP93 | |
| B | ASP95 | |
| B | ASP97 | |
| B | TYR99 | |
| B | GLU104 | |
| B | ASP129 | |
| B | ASP131 | |
| B | ASP133 | |
| B | GLN135 | |
| I | PRO14 | |
| B | GLU140 | |
| C | ASP20 | |
| C | ASP22 | |
| C | ASP24 | |
| C | THR26 | |
| C | GLU31 | |
| C | ASP56 | |
| C | ASP58 | |
| C | ASN60 | |
| C | THR62 | |
| A | GLU31 | |
| C | GLU67 | |
| C | ASP93 | |
| C | ASP95 | |
| C | ASP97 | |
| C | TYR99 | |
| C | GLU104 | |
| C | ASP129 | |
| C | ASP131 | |
| C | ASP133 | |
| C | GLN135 | |
| A | ASP56 | |
| C | GLU140 | |
| D | ASP20 | |
| D | ASP22 | |
| D | ASP24 | |
| D | THR26 | |
| D | GLU31 | |
| D | ASP56 | |
| D | ASP58 | |
| D | ASN60 | |
| D | THR62 | |
| A | ASP58 | |
| D | GLU67 | |
| D | ASP93 | |
| D | ASP95 | |
| D | ASP97 | |
| D | TYR99 | |
| D | GLU104 | |
| D | ASP129 | |
| D | ASP131 | |
| D | ASP133 | |
| D | GLN135 | |
| A | ASN60 | |
| D | GLU140 | |
| A | THR62 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | MOD_RES: N-formylglycine; partial => ECO:0000269|PubMed:5139483 |
| Chain | Residue | Details |
| F | GLY1 | |
| G | GLY1 | |
| H | GLY1 | |
| I | GLY1 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | MOD_RES: Glutamine amide => ECO:0000269|PubMed:5592400 |
| Chain | Residue | Details |
| F | GLN26 | |
| G | GLN26 | |
| H | GLN26 | |
| I | GLN26 |
