8AG1

Crystal structure of a novel OX40 antibody

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005031	molecular_function	tumor necrosis factor receptor activity
A	0006954	biological_process	inflammatory response
a	0005031	molecular_function	tumor necrosis factor receptor activity
a	0006954	biological_process	inflammatory response

Functional Information from PROSITE/UniProt

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YACEVTH

Chain	Residue	Details
L	TYR194-HIS200
H	TYR200-HIS206

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site_id	PS00652
Number of Residues	34
Details	TNFR_NGFR_1 TNFR/NGFR family cysteine-rich region signature. Cvgdt..Ypsndr.....C..Che.Crpgnglvsr..Csrsq..NTVC

Chain	Residue	Details
A	CYS31-CYS64
A	CYS64-CYS107

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	35
Details	Repeat: {"description":"TNFR-Cys 1"}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	41
Details	Repeat: {"description":"TNFR-Cys 2"}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	18
Details	Repeat: {"description":"TNFR-Cys 3; truncated"}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	2
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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