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8AE6

Cryo-EM structure of the SEA complex wing (SEACIT)

Functional Information from GO Data
ChainGOidnamespacecontents
Q0000329cellular_componentfungal-type vacuole membrane
Q0005515molecular_functionprotein binding
Q0005774cellular_componentvacuolar membrane
Q0008270molecular_functionzinc ion binding
Q0015031biological_processprotein transport
Q0034198biological_processcellular response to amino acid starvation
Q0035591molecular_functionsignaling adaptor activity
Q0035859cellular_componentSeh1-associated complex
Q1903432biological_processregulation of TORC1 signaling
Q1904263biological_processpositive regulation of TORC1 signaling
S0003674molecular_functionmolecular_function
S0005096molecular_functionGTPase activator activity
S0005515molecular_functionprotein binding
S0005774cellular_componentvacuolar membrane
S0006351biological_processDNA-templated transcription
S0006995biological_processcellular response to nitrogen starvation
S0009410biological_processresponse to xenobiotic stimulus
S0010508biological_processpositive regulation of autophagy
S0015031biological_processprotein transport
S0015824biological_processproline transport
S0015840biological_processurea transport
S0034198biological_processcellular response to amino acid starvation
S0035859cellular_componentSeh1-associated complex
S1903432biological_processregulation of TORC1 signaling
S1904262biological_processnegative regulation of TORC1 signaling
S1990130cellular_componentGATOR1 complex
S2000785biological_processregulation of autophagosome assembly
U0032007biological_processnegative regulation of TOR signaling
W0000329cellular_componentfungal-type vacuole membrane
W0005096molecular_functionGTPase activator activity
W0005515molecular_functionprotein binding
W0005774cellular_componentvacuolar membrane
W0006995biological_processcellular response to nitrogen starvation
W0010508biological_processpositive regulation of autophagy
W0015031biological_processprotein transport
W0030695molecular_functionGTPase regulator activity
W0032007biological_processnegative regulation of TOR signaling
W0034599biological_processcellular response to oxidative stress
W0035556biological_processintracellular signal transduction
W0035859cellular_componentSeh1-associated complex
W0051058biological_processnegative regulation of small GTPase mediated signal transduction
W1903432biological_processregulation of TORC1 signaling
W1904262biological_processnegative regulation of TORC1 signaling
W1990130cellular_componentGATOR1 complex
W2000785biological_processregulation of autophagosome assembly
Functional Information from PROSITE/UniProt
site_idPS00678
Number of Residues15
DetailsWD_REPEATS_1 Trp-Asp (WD) repeats signature. LATCsvDtYVHAWDM
ChainResidueDetails
QLEU130-MET144

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues43
DetailsRepeat: {"description":"WD 1"}
ChainResidueDetails

site_idSWS_FT_FI2
Number of Residues40
DetailsRepeat: {"description":"WD 2"}
ChainResidueDetails

site_idSWS_FT_FI3
Number of Residues39
DetailsRepeat: {"description":"WD 3"}
ChainResidueDetails

site_idSWS_FT_FI4
Number of Residues40
DetailsRepeat: {"description":"WD 4"}
ChainResidueDetails

site_idSWS_FT_FI5
Number of Residues49
DetailsRepeat: {"description":"WD 5"}
ChainResidueDetails

247536

PDB entries from 2026-01-14

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