Functional Information from GO Data
| Chain | GOid | namespace | contents |
| AAA | 0004322 | molecular_function | ferroxidase activity |
| AAA | 0005506 | molecular_function | iron ion binding |
| AAA | 0005515 | molecular_function | protein binding |
| AAA | 0005576 | cellular_component | extracellular region |
| AAA | 0005634 | cellular_component | nucleus |
| AAA | 0005737 | cellular_component | cytoplasm |
| AAA | 0005764 | cellular_component | lysosome |
| AAA | 0005776 | cellular_component | autophagosome |
| AAA | 0005829 | cellular_component | cytosol |
| AAA | 0006826 | biological_process | iron ion transport |
| AAA | 0006879 | biological_process | intracellular iron ion homeostasis |
| AAA | 0006955 | biological_process | immune response |
| AAA | 0008198 | molecular_function | ferrous iron binding |
| AAA | 0008199 | molecular_function | ferric iron binding |
| AAA | 0008285 | biological_process | negative regulation of cell population proliferation |
| AAA | 0016491 | molecular_function | oxidoreductase activity |
| AAA | 0031410 | cellular_component | cytoplasmic vesicle |
| AAA | 0042802 | molecular_function | identical protein binding |
| AAA | 0044754 | cellular_component | autolysosome |
| AAA | 0046872 | molecular_function | metal ion binding |
| AAA | 0048147 | biological_process | negative regulation of fibroblast proliferation |
| AAA | 0070062 | cellular_component | extracellular exosome |
| AAA | 0070288 | cellular_component | ferritin complex |
| AAA | 0110076 | biological_process | negative regulation of ferroptosis |
| AAA | 0140315 | molecular_function | iron ion sequestering activity |
| AAA | 1904724 | cellular_component | tertiary granule lumen |
| AAA | 1904813 | cellular_component | ficolin-1-rich granule lumen |
Functional Information from PROSITE/UniProt
| site_id | PS00204 |
| Number of Residues | 21 |
| Details | FERRITIN_2 Ferritin iron-binding regions signature 2. DphLCDFIEthYLneqvkaIK |
| Chain | Residue | Details |
| AAA | ASP126-LYS146 | |
| site_id | PS00540 |
| Number of Residues | 19 |
| Details | FERRITIN_1 Ferritin iron-binding regions signature 1. EeREhaEKLMklQNqRgGR |
| Chain | Residue | Details |
| AAA | GLU61-ARG79 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 149 |
| Details | Domain: {"description":"Ferritin-like diiron","evidences":[{"source":"PROSITE-ProRule","id":"PRU00085","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"1992356","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1FHA","evidenceCode":"ECO:0007744"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 3 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00085","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Site: {"description":"Essential for association with cargo receptor NCOA4","evidences":[{"source":"PubMed","id":"26436293","evidenceCode":"ECO:0000269"}]} |
