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8A4C

Structure of human Rep15:Rab3B complex.

Functional Information from GO Data
ChainGOidnamespacecontents
A0001881biological_processreceptor recycling
A0005515molecular_functionprotein binding
A0005768cellular_componentendosome
A0010008cellular_componentendosome membrane
A0016020cellular_componentmembrane
A0031901cellular_componentearly endosome membrane
A0033572biological_processtransferrin transport
A0048471cellular_componentperinuclear region of cytoplasm
A0055037cellular_componentrecycling endosome
B0000166molecular_functionnucleotide binding
B0003924molecular_functionGTPase activity
B0005515molecular_functionprotein binding
B0005525molecular_functionGTP binding
B0005737cellular_componentcytoplasm
B0005768cellular_componentendosome
B0005794cellular_componentGolgi apparatus
B0005886cellular_componentplasma membrane
B0006887biological_processexocytosis
B0008021cellular_componentsynaptic vesicle
B0015031biological_processprotein transport
B0016020cellular_componentmembrane
B0016787molecular_functionhydrolase activity
B0017157biological_processregulation of exocytosis
B0019003molecular_functionGDP binding
B0019882biological_processantigen processing and presentation
B0030141cellular_componentsecretory granule
B0030672cellular_componentsynaptic vesicle membrane
B0030742molecular_functionGTP-dependent protein binding
B0031489molecular_functionmyosin V binding
B0031982cellular_componentvesicle
B0048471cellular_componentperinuclear region of cytoplasm
B0051586biological_processpositive regulation of dopamine uptake involved in synaptic transmission
B0070062cellular_componentextracellular exosome
B0097494biological_processregulation of vesicle size
B0098691cellular_componentdopaminergic synapse
B0098693biological_processregulation of synaptic vesicle cycle
C0001881biological_processreceptor recycling
C0005515molecular_functionprotein binding
C0005768cellular_componentendosome
C0010008cellular_componentendosome membrane
C0016020cellular_componentmembrane
C0031901cellular_componentearly endosome membrane
C0033572biological_processtransferrin transport
C0048471cellular_componentperinuclear region of cytoplasm
C0055037cellular_componentrecycling endosome
D0000166molecular_functionnucleotide binding
D0003924molecular_functionGTPase activity
D0005515molecular_functionprotein binding
D0005525molecular_functionGTP binding
D0005737cellular_componentcytoplasm
D0005768cellular_componentendosome
D0005794cellular_componentGolgi apparatus
D0005886cellular_componentplasma membrane
D0006887biological_processexocytosis
D0008021cellular_componentsynaptic vesicle
D0015031biological_processprotein transport
D0016020cellular_componentmembrane
D0016787molecular_functionhydrolase activity
D0017157biological_processregulation of exocytosis
D0019003molecular_functionGDP binding
D0019882biological_processantigen processing and presentation
D0030141cellular_componentsecretory granule
D0030672cellular_componentsynaptic vesicle membrane
D0030742molecular_functionGTP-dependent protein binding
D0031489molecular_functionmyosin V binding
D0031982cellular_componentvesicle
D0048471cellular_componentperinuclear region of cytoplasm
D0051586biological_processpositive regulation of dopamine uptake involved in synaptic transmission
D0070062cellular_componentextracellular exosome
D0097494biological_processregulation of vesicle size
D0098691cellular_componentdopaminergic synapse
D0098693biological_processregulation of synaptic vesicle cycle
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues28
DetailsBINDING: BINDING => ECO:0000269|PubMed:35871249, ECO:0007744|PDB:8A4B
ChainResidueDetails
BSER31
BASN135
BLYS136
BASP138
BALA166
BLYS167
DSER31
DSER32
DVAL33
DGLY34
DLYS35
BSER32
DSER37
DPRO49
DSER53
DGLY80
DASN135
DLYS136
DASP138
DALA166
DLYS167
BVAL33
BGLY34
BLYS35
BSER37
BPRO49
BSER53
BGLY80

site_idSWS_FT_FI2
Number of Residues4
DetailsBINDING: BINDING => ECO:0000269|PubMed:35871249, ECO:0007744|PDB:8A4B, ECO:0007744|PDB:8A4C
ChainResidueDetails
BTHR36
BTHR54
DTHR36
DTHR54

site_idSWS_FT_FI3
Number of Residues2
DetailsBINDING: BINDING => ECO:0007744|PDB:8A4B, ECO:0007744|PDB:8A4C
ChainResidueDetails
BASP77
DASP77

site_idSWS_FT_FI4
Number of Residues2
DetailsBINDING: BINDING => ECO:0000269|Ref.7, ECO:0007744|PDB:3DZ8
ChainResidueDetails
BMET139
DMET139

site_idSWS_FT_FI5
Number of Residues2
DetailsMOD_RES: N-acetylalanine => ECO:0000250|UniProtKB:O95716
ChainResidueDetails
BALA2
DALA2

site_idSWS_FT_FI6
Number of Residues2
DetailsMOD_RES: Phosphothreonine; by LRRK2 => ECO:0000269|PubMed:29125462
ChainResidueDetails
BTHR86
DTHR86

site_idSWS_FT_FI7
Number of Residues2
DetailsMOD_RES: Phosphoserine => ECO:0000250|UniProtKB:Q63941
ChainResidueDetails
BSER188
DSER188

site_idSWS_FT_FI8
Number of Residues2
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:21406692
ChainResidueDetails
BSER190
DSER190

site_idSWS_FT_FI9
Number of Residues2
DetailsMOD_RES: Cysteine methyl ester => ECO:0000250
ChainResidueDetails
BCYS219
DCYS219

site_idSWS_FT_FI10
Number of Residues4
DetailsLIPID: S-geranylgeranyl cysteine => ECO:0000250
ChainResidueDetails
BCYS217
BCYS219
DCYS217
DCYS219

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PDB entries from 2025-06-18

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