7ZX1

Crystal structure of Pol theta polymerase domain in complex with compound 22

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
AAA	0003676	molecular_function	nucleic acid binding
AAA	0003677	molecular_function	DNA binding
AAA	0003887	molecular_function	DNA-directed DNA polymerase activity
AAA	0006260	biological_process	DNA replication
AAA	0006261	biological_process	DNA-templated DNA replication
BBB	0003676	molecular_function	nucleic acid binding
BBB	0003677	molecular_function	DNA binding
BBB	0003887	molecular_function	DNA-directed DNA polymerase activity
BBB	0006260	biological_process	DNA replication
BBB	0006261	biological_process	DNA-templated DNA replication
CCC	0003676	molecular_function	nucleic acid binding
CCC	0003677	molecular_function	DNA binding
CCC	0003887	molecular_function	DNA-directed DNA polymerase activity
CCC	0006260	biological_process	DNA replication
CCC	0006261	biological_process	DNA-templated DNA replication
DDD	0003676	molecular_function	nucleic acid binding
DDD	0003677	molecular_function	DNA binding
DDD	0003887	molecular_function	DNA-directed DNA polymerase activity
DDD	0006260	biological_process	DNA replication
DDD	0006261	biological_process	DNA-templated DNA replication
EEE	0003676	molecular_function	nucleic acid binding
EEE	0003677	molecular_function	DNA binding
EEE	0003887	molecular_function	DNA-directed DNA polymerase activity
EEE	0006260	biological_process	DNA replication
EEE	0006261	biological_process	DNA-templated DNA replication
FFF	0003676	molecular_function	nucleic acid binding
FFF	0003677	molecular_function	DNA binding
FFF	0003887	molecular_function	DNA-directed DNA polymerase activity
FFF	0006260	biological_process	DNA replication
FFF	0006261	biological_process	DNA-templated DNA replication

Functional Information from PROSITE/UniProt

site_id	PS00447
Number of Residues	20
Details	DNA_POLYMERASE_A DNA polymerase family A signature. RqqAKqicYGiiYgmGaksL

Chain	Residue	Details
AAA	ARG2379-LEU2398

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	18
Details	BINDING: BINDING => ECO:0000269|PubMed:25775267, ECO:0007744|PDB:4X0Q

Chain	Residue	Details
AAA	GLY2375
DDD	GLY2375
DDD	ASP2376
DDD	LEU2585
EEE	GLY2375
EEE	ASP2376
EEE	LEU2585
FFF	GLY2375
FFF	ASP2376
FFF	LEU2585
AAA	ASP2376
AAA	LEU2585
BBB	GLY2375
BBB	ASP2376
BBB	LEU2585
CCC	GLY2375
CCC	ASP2376
CCC	LEU2585

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