7ZW3

Crystal Structure of human MAO B in complex with (Z)-N-benzyl-1-(8-hydroxyquinolin-2-yl)methanimine oxide (inhibitor 19)

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
AAA	0005515	molecular_function	protein binding
AAA	0005739	cellular_component	mitochondrion
AAA	0005740	cellular_component	mitochondrial envelope
AAA	0005741	cellular_component	mitochondrial outer membrane
AAA	0008131	molecular_function	primary methylamine oxidase activity
AAA	0009055	molecular_function	electron transfer activity
AAA	0016020	cellular_component	membrane
AAA	0016491	molecular_function	oxidoreductase activity
AAA	0021762	biological_process	substantia nigra development
AAA	0042420	biological_process	dopamine catabolic process
AAA	0050660	molecular_function	flavin adenine dinucleotide binding
AAA	0050665	biological_process	hydrogen peroxide biosynthetic process
AAA	0097621	molecular_function	monoamine oxidase activity
BBB	0005515	molecular_function	protein binding
BBB	0005739	cellular_component	mitochondrion
BBB	0005740	cellular_component	mitochondrial envelope
BBB	0005741	cellular_component	mitochondrial outer membrane
BBB	0008131	molecular_function	primary methylamine oxidase activity
BBB	0009055	molecular_function	electron transfer activity
BBB	0016020	cellular_component	membrane
BBB	0016491	molecular_function	oxidoreductase activity
BBB	0021762	biological_process	substantia nigra development
BBB	0042420	biological_process	dopamine catabolic process
BBB	0050660	molecular_function	flavin adenine dinucleotide binding
BBB	0050665	biological_process	hydrogen peroxide biosynthetic process
BBB	0097621	molecular_function	monoamine oxidase activity

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	974
Details	Topological domain: {"description":"Cytoplasmic"}

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site_id	SWS_FT_FI2
Number of Residues	6
Details	Site: {"description":"Important for catalytic activity"}

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site_id	SWS_FT_FI3
Number of Residues	2
Details	Modified residue: {"description":"N-acetylserine","evidences":[{"source":"PubMed","id":"11049757","evidenceCode":"ECO:0000269"}]}

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site_id	SWS_FT_FI4
Number of Residues	2
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"Q8BW75","evidenceCode":"ECO:0000250"}]}

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site_id	SWS_FT_FI5
Number of Residues	2
Details	Modified residue: {"description":"S-8alpha-FAD cysteine","evidences":[{"source":"PubMed","id":"11753429","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"12913124","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"15027868","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"15710600","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16366596","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1GOS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1OJ9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1OJA","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1OJC","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1OJD","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1S2Q","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1S2Y","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1S3B","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1S3E","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2BK3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2BK4","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2BK5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2BYB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2C64","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2C65","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2C66","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2C67","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2C70","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2C72","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2C73","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2C75","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2C76","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2V5Z","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2V60","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2V61","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2VRL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2VRM","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2VZ2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2XFN","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2XFO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2XFP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2XFQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PO7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3ZYX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4A79","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4A7A","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4CRT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5MRL","evidenceCode":"ECO:0007744"}]}

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