7ZU0

HOPS tethering complex from yeast

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000329	cellular_component	fungal-type vacuole membrane
A	0005515	molecular_function	protein binding
A	0005768	cellular_component	endosome
A	0005774	cellular_component	vacuolar membrane
A	0005829	cellular_component	cytosol
A	0006886	biological_process	intracellular protein transport
A	0006895	biological_process	Golgi to endosome transport
A	0006904	biological_process	vesicle docking involved in exocytosis
A	0007032	biological_process	endosome organization
A	0007033	biological_process	vacuole organization
A	0008270	molecular_function	zinc ion binding
A	0015031	biological_process	protein transport
A	0016192	biological_process	vesicle-mediated transport
A	0016740	molecular_function	transferase activity
A	0030674	molecular_function	protein-macromolecule adaptor activity
A	0030897	cellular_component	HOPS complex
A	0031901	cellular_component	early endosome membrane
A	0032889	biological_process	regulation of vacuole fusion, non-autophagic
A	0033263	cellular_component	CORVET complex
A	0035091	molecular_function	phosphatidylinositol binding
A	0035542	biological_process	regulation of SNARE complex assembly
A	0036205	biological_process	histone catabolic process
A	0042144	biological_process	vacuole fusion, non-autophagic
A	0045324	biological_process	late endosome to vacuole transport
A	0046872	molecular_function	metal ion binding
A	0048284	biological_process	organelle fusion
A	0061630	molecular_function	ubiquitin protein ligase activity
A	0098588	cellular_component	bounding membrane of organelle
A	0099022	biological_process	vesicle tethering
A	0099023	cellular_component	vesicle tethering complex
B	0000329	cellular_component	fungal-type vacuole membrane
B	0003779	molecular_function	actin binding
B	0005515	molecular_function	protein binding
B	0005737	cellular_component	cytoplasm
B	0005768	cellular_component	endosome
B	0005773	cellular_component	vacuole
B	0005829	cellular_component	cytosol
B	0006623	biological_process	protein targeting to vacuole
B	0006886	biological_process	intracellular protein transport
B	0006895	biological_process	Golgi to endosome transport
B	0007033	biological_process	vacuole organization
B	0015031	biological_process	protein transport
B	0016020	cellular_component	membrane
B	0016197	biological_process	endosomal transport
B	0030897	cellular_component	HOPS complex
B	0031901	cellular_component	early endosome membrane
B	0032889	biological_process	regulation of vacuole fusion, non-autophagic
B	0033263	cellular_component	CORVET complex
B	0035091	molecular_function	phosphatidylinositol binding
B	0035542	biological_process	regulation of SNARE complex assembly
B	0042144	biological_process	vacuole fusion, non-autophagic
B	0045324	biological_process	late endosome to vacuole transport
B	0099022	biological_process	vesicle tethering
B	0099023	cellular_component	vesicle tethering complex
C	0000329	cellular_component	fungal-type vacuole membrane
C	0005515	molecular_function	protein binding
C	0005768	cellular_component	endosome
C	0005774	cellular_component	vacuolar membrane
C	0005829	cellular_component	cytosol
C	0006886	biological_process	intracellular protein transport
C	0006895	biological_process	Golgi to endosome transport
C	0006904	biological_process	vesicle docking involved in exocytosis
C	0007032	biological_process	endosome organization
C	0007033	biological_process	vacuole organization
C	0008270	molecular_function	zinc ion binding
C	0015031	biological_process	protein transport
C	0016192	biological_process	vesicle-mediated transport
C	0030674	molecular_function	protein-macromolecule adaptor activity
C	0030897	cellular_component	HOPS complex
C	0031901	cellular_component	early endosome membrane
C	0032889	biological_process	regulation of vacuole fusion, non-autophagic
C	0033263	cellular_component	CORVET complex
C	0035091	molecular_function	phosphatidylinositol binding
C	0035542	biological_process	regulation of SNARE complex assembly
C	0042144	biological_process	vacuole fusion, non-autophagic
C	0045324	biological_process	late endosome to vacuole transport
C	0046872	molecular_function	metal ion binding
C	0048284	biological_process	organelle fusion
C	0098588	cellular_component	bounding membrane of organelle
C	0099022	biological_process	vesicle tethering
D	0000324	cellular_component	fungal-type vacuole
D	0000329	cellular_component	fungal-type vacuole membrane
D	0005515	molecular_function	protein binding
D	0005524	molecular_function	ATP binding
D	0005773	cellular_component	vacuole
D	0005829	cellular_component	cytosol
D	0006623	biological_process	protein targeting to vacuole
D	0006886	biological_process	intracellular protein transport
D	0006896	biological_process	Golgi to vacuole transport
D	0006897	biological_process	endocytosis
D	0007033	biological_process	vacuole organization
D	0015031	biological_process	protein transport
D	0016192	biological_process	vesicle-mediated transport
D	0030897	cellular_component	HOPS complex
D	0031901	cellular_component	early endosome membrane
D	0032889	biological_process	regulation of vacuole fusion, non-autophagic
D	0033263	cellular_component	CORVET complex
D	0034727	biological_process	piecemeal microautophagy of the nucleus
D	0035091	molecular_function	phosphatidylinositol binding
D	0035542	biological_process	regulation of SNARE complex assembly
D	0042144	biological_process	vacuole fusion, non-autophagic
D	0048278	biological_process	vesicle docking
D	0051469	biological_process	vesicle fusion with vacuole
D	0099022	biological_process	vesicle tethering
E	0000324	cellular_component	fungal-type vacuole
E	0000329	cellular_component	fungal-type vacuole membrane
E	0005085	molecular_function	guanyl-nucleotide exchange factor activity
E	0005515	molecular_function	protein binding
E	0005737	cellular_component	cytoplasm
E	0005774	cellular_component	vacuolar membrane
E	0006886	biological_process	intracellular protein transport
E	0007033	biological_process	vacuole organization
E	0015031	biological_process	protein transport
E	0016192	biological_process	vesicle-mediated transport
E	0030897	cellular_component	HOPS complex
E	0031267	molecular_function	small GTPase binding
E	0034727	biological_process	piecemeal microautophagy of the nucleus
E	0035091	molecular_function	phosphatidylinositol binding
E	0035542	biological_process	regulation of SNARE complex assembly
E	0042144	biological_process	vacuole fusion, non-autophagic
E	0097352	biological_process	autophagosome maturation
E	0097576	biological_process	vacuole fusion
E	0098588	cellular_component	bounding membrane of organelle
E	0099022	biological_process	vesicle tethering
E	1904263	biological_process	positive regulation of TORC1 signaling
E	1990816	cellular_component	vacuole-mitochondrion membrane contact site
F	0000329	cellular_component	fungal-type vacuole membrane
F	0005515	molecular_function	protein binding
F	0005768	cellular_component	endosome
F	0005770	cellular_component	late endosome
F	0005773	cellular_component	vacuole
F	0005774	cellular_component	vacuolar membrane
F	0006623	biological_process	protein targeting to vacuole
F	0006624	biological_process	vacuolar protein processing
F	0006886	biological_process	intracellular protein transport
F	0007033	biological_process	vacuole organization
F	0007034	biological_process	vacuolar transport
F	0009267	biological_process	cellular response to starvation
F	0015031	biological_process	protein transport
F	0016192	biological_process	vesicle-mediated transport
F	0016236	biological_process	macroautophagy
F	0030897	cellular_component	HOPS complex
F	0031267	molecular_function	small GTPase binding
F	0032258	biological_process	cytoplasm to vacuole targeting by the Cvt pathway
F	0034058	biological_process	endosomal vesicle fusion
F	0034727	biological_process	piecemeal microautophagy of the nucleus
F	0035091	molecular_function	phosphatidylinositol binding
F	0035542	biological_process	regulation of SNARE complex assembly
F	0042144	biological_process	vacuole fusion, non-autophagic
F	0043495	molecular_function	protein-membrane adaptor activity
F	0046907	biological_process	intracellular transport
F	0098588	cellular_component	bounding membrane of organelle
F	0099022	biological_process	vesicle tethering

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	177
Details	Repeat: {"description":"CHCR","evidences":[{"source":"PROSITE-ProRule","id":"PRU01006","evidenceCode":"ECO:0000255"}]}

Chain

Residue

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site_id	SWS_FT_FI2
Number of Residues	45
Details	Zinc finger: {"description":"RING-type","evidences":[{"source":"PROSITE-ProRule","id":"PRU00175","evidenceCode":"ECO:0000255"}]}

Chain

Residue

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site_id	SWS_FT_FI3
Number of Residues	156
Details	Repeat: {"description":"CHCR"}

Chain

Residue

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site_id	SWS_FT_FI4
Number of Residues	25
Details	Zinc finger: {"description":"RING-type; atypical"}

Chain

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site_id	SWS_FT_FI5
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"18407956","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"19779198","evidenceCode":"ECO:0007744"}]}

Chain

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