7ZMN
Crystal structure of human RECQL5 helicase APO form in complex with engineered nanobody (Gluebody) G3-048
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003676 | molecular_function | nucleic acid binding |
| A | 0004386 | molecular_function | helicase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006310 | biological_process | DNA recombination |
| B | 0003676 | molecular_function | nucleic acid binding |
| B | 0004386 | molecular_function | helicase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0006310 | biological_process | DNA recombination |
Functional Information from PROSITE/UniProt
| site_id | PS00690 |
| Number of Residues | 10 |
| Details | DEAH_ATP_HELICASE DEAH-box subfamily ATP-dependent helicases signature. SyLVVDEAHC |
| Chain | Residue | Details |
| A | SER152-CYS161 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 348 |
| Details | Domain: {"description":"Helicase ATP-binding","evidences":[{"source":"PROSITE-ProRule","id":"PRU00541","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 324 |
| Details | Domain: {"description":"Helicase C-terminal","evidences":[{"source":"PROSITE-ProRule","id":"PRU00542","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 6 |
| Details | Motif: {"description":"DEAH box"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 18 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"28100692","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"5LB3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5LB5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5LBA","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PDB","id":"5LB5","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 6 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"28100692","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5LB3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5LB5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5LB8","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5LBA","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"28100692","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5LB3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5LB5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5LBA","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
