7ZMN
Crystal structure of human RECQL5 helicase APO form in complex with engineered nanobody (Gluebody) G3-048
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0003676 | molecular_function | nucleic acid binding |
A | 0004386 | molecular_function | helicase activity |
A | 0005524 | molecular_function | ATP binding |
A | 0006310 | biological_process | DNA recombination |
B | 0003676 | molecular_function | nucleic acid binding |
B | 0004386 | molecular_function | helicase activity |
B | 0005524 | molecular_function | ATP binding |
B | 0006310 | biological_process | DNA recombination |
Functional Information from PROSITE/UniProt
site_id | PS00690 |
Number of Residues | 10 |
Details | DEAH_ATP_HELICASE DEAH-box subfamily ATP-dependent helicases signature. SyLVVDEAHC |
Chain | Residue | Details |
A | SER152-CYS161 |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 18 |
Details | BINDING: BINDING => ECO:0000305|PubMed:28100692, ECO:0007744|PDB:5LB3, ECO:0007744|PDB:5LB5, ECO:0007744|PDB:5LBA |
Chain | Residue | Details |
A | PHE26 | |
B | PHE26 | |
B | SER28 | |
B | LYS30 | |
B | GLN34 | |
B | GLY55 | |
B | ALA56 | |
B | GLY57 | |
B | LYS58 | |
B | SER59 | |
A | SER28 | |
A | LYS30 | |
A | GLN34 | |
A | GLY55 | |
A | ALA56 | |
A | GLY57 | |
A | LYS58 | |
A | SER59 |
site_id | SWS_FT_FI2 |
Number of Residues | 2 |
Details | BINDING: BINDING => ECO:0007744|PDB:5LB5 |
Chain | Residue | Details |
A | PRO53 | |
B | PRO53 |
site_id | SWS_FT_FI3 |
Number of Residues | 6 |
Details | BINDING: BINDING => ECO:0000269|PubMed:28100692, ECO:0007744|PDB:5LB3, ECO:0007744|PDB:5LB5, ECO:0007744|PDB:5LB8, ECO:0007744|PDB:5LBA |
Chain | Residue | Details |
A | CYS411 | |
A | CYS431 | |
A | CYS434 | |
B | CYS411 | |
B | CYS431 | |
B | CYS434 |
site_id | SWS_FT_FI4 |
Number of Residues | 2 |
Details | BINDING: BINDING => ECO:0000269|PubMed:28100692, ECO:0007744|PDB:5LB3, ECO:0007744|PDB:5LB5, ECO:0007744|PDB:5LBA |
Chain | Residue | Details |
A | CYS427 | |
B | CYS427 |