7ZM8

CryoEM structure of mitochondrial complex I from Chaetomium thermophilum (inhibited by DDM) - membrane arm

Functional Information from GO Data

Chain	GOid	namespace	contents
1	0003954	molecular_function	NADH dehydrogenase activity
1	0005743	cellular_component	mitochondrial inner membrane
1	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
1	0009060	biological_process	aerobic respiration
1	0016020	cellular_component	membrane
1	1902600	biological_process	proton transmembrane transport
2	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
2	0016020	cellular_component	membrane
2	0042773	biological_process	ATP synthesis coupled electron transport
2	1902600	biological_process	proton transmembrane transport
3	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
3	0016020	cellular_component	membrane
3	0030964	cellular_component	NADH dehydrogenase complex
3	0031966	cellular_component	mitochondrial membrane
3	1902600	biological_process	proton transmembrane transport
4	0003954	molecular_function	NADH dehydrogenase activity
4	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
4	0009060	biological_process	aerobic respiration
4	0015990	biological_process	electron transport coupled proton transport
4	0016020	cellular_component	membrane
4	0031966	cellular_component	mitochondrial membrane
4	0042773	biological_process	ATP synthesis coupled electron transport
4	0048039	molecular_function	ubiquinone binding
5	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
5	0042773	biological_process	ATP synthesis coupled electron transport
6	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
6	0031966	cellular_component	mitochondrial membrane
6	1902600	biological_process	proton transmembrane transport
8	0005739	cellular_component	mitochondrion
8	0005743	cellular_component	mitochondrial inner membrane
8	0005758	cellular_component	mitochondrial intermembrane space
J	0005743	cellular_component	mitochondrial inner membrane
J	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
J	0045271	cellular_component	respiratory chain complex I
L	0005743	cellular_component	mitochondrial inner membrane
L	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
L	0016651	molecular_function	oxidoreductase activity, acting on NAD(P)H
L	0030964	cellular_component	NADH dehydrogenase complex
L	0031966	cellular_component	mitochondrial membrane
L	0042773	biological_process	ATP synthesis coupled electron transport
L	1902600	biological_process	proton transmembrane transport
Q	0000035	molecular_function	acyl binding
Q	0000036	molecular_function	acyl carrier activity
Q	0005739	cellular_component	mitochondrion
Q	0006629	biological_process	lipid metabolic process
Q	0006631	biological_process	fatty acid metabolic process
Q	0006633	biological_process	fatty acid biosynthetic process
Q	0099128	cellular_component	mitochondrial [2Fe-2S] assembly complex
R	0005743	cellular_component	mitochondrial inner membrane
R	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
U	0005743	cellular_component	mitochondrial inner membrane
U	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
W	0005739	cellular_component	mitochondrion
W	0005743	cellular_component	mitochondrial inner membrane
W	0016020	cellular_component	membrane
W	0045271	cellular_component	respiratory chain complex I
a	0005739	cellular_component	mitochondrion
c	0005739	cellular_component	mitochondrion
c	0005743	cellular_component	mitochondrial inner membrane
c	0022900	biological_process	electron transport chain
c	0032981	biological_process	mitochondrial respiratory chain complex I assembly
d	0005743	cellular_component	mitochondrial inner membrane
e	0005743	cellular_component	mitochondrial inner membrane
e	0045271	cellular_component	respiratory chain complex I
n	0005739	cellular_component	mitochondrion

Functional Information from PROSITE/UniProt

site_id	PS00012
Number of Residues	16
Details	PHOSPHOPANTETHEINE Phosphopantetheine attachment site. DLGLDSLDTVEVVMAI

Chain	Residue	Details
Q	ASP93-ILE108

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site_id	PS00667
Number of Residues	16
Details	COMPLEX1_ND1_1 Respiratory-chain NADH dehydrogenase subunit 1 signature 1. GLLQaFaDALKLLlKE

Chain	Residue	Details
1	GLY51-GLU66

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site_id	PS00668
Number of Residues	14
Details	COMPLEX1_ND1_2 Respiratory-chain NADH dehydrogenase subunit 1 signature 2. PFDLAEAEseLVs.G

Chain	Residue	Details
1	PRO206-GLY219

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