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7ZLG

Cryo-EM structure of C-mannosyltransferase CeDPY19, in complex with acceptor peptide and bound to CMT2-Fab and anti-Fab nanobody

Functional Information from GO Data
ChainGOidnamespacecontents
A0000030molecular_functionmannosyltransferase activity
A0005637cellular_componentnuclear inner membrane
A0005737cellular_componentcytoplasm
A0005783cellular_componentendoplasmic reticulum
A0005789cellular_componentendoplasmic reticulum membrane
A0005975biological_processcarbohydrate metabolic process
A0007399biological_processnervous system development
A0016020cellular_componentmembrane
A0016757molecular_functionglycosyltransferase activity
A0018406biological_processprotein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan
A0030154biological_processcell differentiation
A0048471cellular_componentperinuclear region of cytoplasm
L0005576cellular_componentextracellular region
Functional Information from PROSITE/UniProt
site_idPS00290
Number of Residues7
DetailsIG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YICNVNH
ChainResidueDetails
HTYR209-HIS215
LTYR193-HIS199

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues220
DetailsTRANSMEM: Helical => ECO:0000255
ChainResidueDetails
ASER21-ILE41
APHE467-PHE487
AILE502-ILE522
AILE167-LEU187
AVAL188-GLU208
AGLU220-TYR240
APHE267-PHE287
AILE298-LEU318
ATYR319-LEU339
AALA344-LEU364
ACYS413-VAL433

223790

PDB entries from 2024-08-14

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