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7ZKP

Late assembly intermediate of the proximal proton pumping module of complex I with assembly factors NDUFAF1 and CIA84

Functional Information from GO Data
ChainGOidnamespacecontents
10003954molecular_functionNADH dehydrogenase activity
10005739cellular_componentmitochondrion
10005743cellular_componentmitochondrial inner membrane
10008137molecular_functionNADH dehydrogenase (ubiquinone) activity
10009060biological_processaerobic respiration
10016020cellular_componentmembrane
10045271cellular_componentrespiratory chain complex I
11902600biological_processproton transmembrane transport
20005739cellular_componentmitochondrion
20005743cellular_componentmitochondrial inner membrane
20008137molecular_functionNADH dehydrogenase (ubiquinone) activity
20016020cellular_componentmembrane
20022904biological_processrespiratory electron transport chain
20045271cellular_componentrespiratory chain complex I
21902600biological_processproton transmembrane transport
30005739cellular_componentmitochondrion
30008137molecular_functionNADH dehydrogenase (ubiquinone) activity
30016020cellular_componentmembrane
30031966cellular_componentmitochondrial membrane
30045271cellular_componentrespiratory chain complex I
31902600biological_processproton transmembrane transport
60005739cellular_componentmitochondrion
60008137molecular_functionNADH dehydrogenase (ubiquinone) activity
60016020cellular_componentmembrane
60031966cellular_componentmitochondrial membrane
61902600biological_processproton transmembrane transport
90005739cellular_componentmitochondrion
90005743cellular_componentmitochondrial inner membrane
90005758cellular_componentmitochondrial intermembrane space
90016020cellular_componentmembrane
90032981biological_processmitochondrial respiratory chain complex I assembly
90045271cellular_componentrespiratory chain complex I
A0005739cellular_componentmitochondrion
A0006120biological_processmitochondrial electron transport, NADH to ubiquinone
A0010257biological_processNADH dehydrogenase complex assembly
A0051082molecular_functionunfolded protein binding
C0003729molecular_functionmRNA binding
C0005739cellular_componentmitochondrion
C0140053biological_processmitochondrial gene expression
D0005739cellular_componentmitochondrion
D0005743cellular_componentmitochondrial inner membrane
D0016020cellular_componentmembrane
D0045271cellular_componentrespiratory chain complex I
g0016020cellular_componentmembrane
L0005739cellular_componentmitochondrion
L0008137molecular_functionNADH dehydrogenase (ubiquinone) activity
L0016020cellular_componentmembrane
L0016651molecular_functionoxidoreductase activity, acting on NAD(P)H
L0031966cellular_componentmitochondrial membrane
L0042773biological_processATP synthesis coupled electron transport
L0045271cellular_componentrespiratory chain complex I
L1902600biological_processproton transmembrane transport
U0005739cellular_componentmitochondrion
U0005743cellular_componentmitochondrial inner membrane
U0006120biological_processmitochondrial electron transport, NADH to ubiquinone
U0016020cellular_componentmembrane
U0045271cellular_componentrespiratory chain complex I
W0005739cellular_componentmitochondrion
W0005743cellular_componentmitochondrial inner membrane
W0016020cellular_componentmembrane
W0045271cellular_componentrespiratory chain complex I
X0016020cellular_componentmembrane
X0045271cellular_componentrespiratory chain complex I
Functional Information from PROSITE/UniProt
site_idPS00133
Number of Residues11
DetailsCARBOXYPEPT_ZN_2 Zinc carboxypeptidases, zinc-binding region 2 signature. HSIAGLFiFPW
ChainResidueDetails
XHIS145-TRP155

site_idPS00667
Number of Residues16
DetailsCOMPLEX1_ND1_1 Respiratory-chain NADH dehydrogenase subunit 1 signature 1. GLLQaFaDAVKLLlKE
ChainResidueDetails
1GLY46-GLU61

site_idPS00668
Number of Residues14
DetailsCOMPLEX1_ND1_2 Respiratory-chain NADH dehydrogenase subunit 1 signature 2. PFDLTESEseLVa.G
ChainResidueDetails
1PRO201-GLY214

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues40
DetailsTRANSMEM: Helical => ECO:0000255
ChainResidueDetails
LASN21-LEU41
2SER317-ILE337
2VAL361-PHE381
2PHE397-LEU417
2TYR441-ILE461
LPHE55-VAL75
6ILE54-ILE74
6LEU94-ASN114
6ALA159-ILE179
2LEU197-LEU217
2ILE230-LEU250
2SER257-LEU277
2LEU284-ASN304

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PDB entries from 2025-06-18

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